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Acquired haemophilia complicating the remission of a patient with high grade non-Hodgkin's lymphoma treated by fludarabine

Lookup NU author(s): Dr Peter Hamilton

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Abstract

We report the development of a high titre antibody to factor VIII in a patient with previous high grade B cell non-Hodgkin's lymphoma treated with fludarabine. Unlike previous reports of factor VIII inhibitors and lymphoproliferative disease this patient's lymphoma was in remission. We speculate that the occurrence of the inhibitor is another manifestation of the increasingly recognized autoimmune side-effects of fludarabine.

Publication metadata

Author(s): Tiplady CW, Hamilton PJ, Galloway MJ

Publication type: Article

Publication status: Published

Journal: Clinical and Laboratory Haematology

Year: 2000

Volume: 22

Issue: 3

Pages: 163-165

ISSN (print): 0141-9854

ISSN (electronic): 1365-2257

Publisher: John Wiley & Sons

URL: http://dx.doi.org/10.1046/j.1365-2257.2000.00308.x

DOI: 10.1046/j.1365-2257.2000.00308.x

PubMed id: 10931166

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