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Lookup NU author(s): Thiloka Ratnaike, Dr Sharmila Das, Dr Barbara Gregson, Emeritus Professor David Mendelow
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OBJECTIVE: The literature regarding surgical treatment of brain abscess was reviewed from 1990 to (and including) 2008 to supplement a previous literature review from 1930 to 1990. METHODS: The Ovid Medline database 1950-2009 with the year range limited to 1990-2009 was used to identify all articles relating to brain abscess. The results were compared with a previously published review from 1930-1990 by the senior author. RESULTS: The original finding was confirmed that the high mortality from aspiration in the pre-computer tomography era decreased dramatically after computer tomographic scanning became available. In the present review, the mean mortality for aspiration post-1990 was 6.6% for publications with more than five patients. With surgical excision by craniotomy, the mean mortality in the same period was 12.7%. CONCLUSIONS: The present review suggests that aspiration may be the first surgical choice in patients with supratentorial parenchymal brain abscesses.
Author(s): Ratnaike TE, Das S, Gregson BA, Mendelow AD
Publication type: Review
Publication status: Published
Journal: World Neurosurgery
Year: 2011
Volume: 76
Issue: 5
Pages: 431-436
Print publication date: 01/11/2011
ISSN (print): 1878-8750
ISSN (electronic): 1878-8769
Publisher: ELSEVIER SCIENCE INC
URL: http://dx.doi.org/10.1016/j.wneu.2011.03.048
DOI: 10.1016/j.wneu.2011.03.048
