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Discovery of 4,6-disubstituted pyrimidines as potent inhibitors of the Heat Shock Factor (HSF1) stress pathway and CDK9

Lookup NU author(s): Dr Julie Tucker, Professor Keith Jones

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Publication metadata

Author(s): Rye C, Chessum N, Lamont S, Pike KG, Faulder P, Demeritt J, Kemmitt P, Tucker J, Zani L, Cheeseman M, Isaac R, Goodwin L, Boros J, Raynaud F, Hayes A, Henley A, deBilly E, Lynch C, Sharp SY, tePoele R, O'Fee L, Foote KM, Green S, Workman P, Jones K

Publication type: Article

Publication status: Published

Journal: MedChemComm

Year: 2016

Volume: 7

Issue: 8

Pages: 1580-1586

Print publication date: 01/08/2016

Online publication date: 13/06/2016

Acceptance date: 07/06/2016

Date deposited: 17/10/2016

ISSN (print): 2040-2503

ISSN (electronic): 2040-2511

Publisher: Royal Society of Chemistry

URL: http://dx.doi.org/10.1039/C6MD00159A

DOI: 10.1039/C6MD00159A


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Funding

Funder referenceFunder name
Institute of Cancer Research
C309/A11566Cancer Research UK
C309/A8274Cancer Research UK
C309/A11566
C309/A8274
C309/A8992

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