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Lookup NU author(s): Dr Jenny Liddle
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
© 2023 The Authors. Musculoskeletal Care published by John Wiley & Sons Ltd.Objectives: The Hip Injection Trial (HIT) compared the effectiveness of adding a single ultrasound-guided intra-articular injection of either corticosteroid and local anaesthetic or local anaesthetic alone to advice and education among people with hip osteoarthritis (OA). This nested qualitative study explored participants' experiences of living with hip OA and of the trial treatment they received. Method: Semi-structured telephone interviews were undertaken with a purposeful sample of trial participants after a 2-month trial follow-up. Interviewers were blinded to which injection participants had received. Thematic analysis using constant comparison was undertaken prior to knowing the trial results. Results: 34 trial participants were interviewed across all arms. OA causes pain, physical limitations, difficulties at work, lowered mood, and disrupted sleep. Those who received advice and education alone felt that they had not received ‘treatment’ and described little/no benefit. Participants in both injection groups described marked improvements in pain, physical function, and other aspects of life (e.g., sleep, confidence). The perceived magnitude of benefit appeared greater among those who received the corticosteroid injection; however, the length of benefit varied in both injection groups. There was uncertainty about the longer-term benefits of injection and repeated injections. Conclusion: Hip OA is highly burdensome. Participants perceived little/no benefit from advice and education alone but reported marked improvements when combined with either injection. However, the magnitude of benefit was greater among those who received corticosteroid. The varying duration of response to injection and uncertainty regarding longer-term benefits of injection and repeated injections suggests that these areas are important for future research. Trial registration: EudraCT 2014-003412-37; ISRCTN50550256.
Author(s): Holden MA, Hawarden A, Paskins Z, Roddy E, Mallen CD, Liddle J, Bourton A, Jinks C
Publication type: Article
Publication status: Published
Journal: Musculoskeletal Care
Year: 2023
Pages: epub ahead of print
Online publication date: 31/10/2023
Acceptance date: 26/09/2023
Date deposited: 14/11/2023
ISSN (print): 1478-2189
ISSN (electronic): 1557-0681
Publisher: John Wiley and Sons Ltd
URL: https://doi.org/10.1002/msc.1830
DOI: 10.1002/msc.1830
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