Browse by author
Lookup NU author(s): Dr Elise Rowan, Dr Christopher Morris, Sally Stephens, Dr Clive Ballard, Dr Heather Dickinson, Dr Harpal Rao, Dr Brian Saxby, Dr Andrew McLaren, Professor Raj KalariaORCiD, Professor Rose Anne Kenny
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
Background and Purpose - The apolipoprotein E4 allele (APOE4) associates with increased dementia risk, and hypertension may associate with mild cognitive deficits. We examined whether nondemented stroke patients with (1) a prestroke history of hypertension and (2) APOE4 were more cognitively impaired at 3 months after stroke. Methods - A total of 257 participants were genotyped and outcomes from neuropsychological evaluations analyzed using regression. Results - Total Cambridge Assessment for Mental Disorders in the Elderly (CAMCOG) and speed of working memory significantly associated with hypertension. No outcomes significantly associated with APOE4. Conclusions - Subjects with prestroke hypertension had more impaired global cognition and slower access to information held in working memory. © 2005 American Heart Association, Inc.
Author(s): Rowan E, Morris CM, Stephens S, Ballard C, Dickinson H, Rao H, Saxby BK, McLaren AT, Kalaria RN, Kenny RA
Publication type: Article
Publication status: Published
Journal: Stroke
Year: 2005
Volume: 36
Issue: 9
Pages: 1864-1868
Print publication date: 28/07/2005
ISSN (print): 0039-2499
ISSN (electronic): 1524-4628
Publisher: Lippincott Williams & Wilkins
URL: http://dx.doi.org/10.1161/01.STR.0000177524.17424.2a
DOI: 10.1161/01.STR.0000177524.17424.2a
PubMed id: 16051894
Altmetrics provided by Altmetric
