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Browsing publications by Dr Christopher Bacon.

Newcastle AuthorsTitleYearFull text
Professor Gareth Veal
Professor Steve Wedge
Dr Christopher Bacon
Professor Philip Sloan
Professor Alastair Greystoke
et al.
A phase I dose-escalation study of AZD3965, an oral monocarboxylate transporter 1 inhibitor, in patients with advanced cancer2023
Dr Christopher Bacon
Correction: “The 5th edition of The World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms” Leukemia. 2022 Jul;36(7):1720–1748 (Leukemia, (2022), 36, 7, (1720-1748), 10.1038/s41375-022-01620-2)2023
Joe O'Donoghue
Dr Christopher Bacon
Dr Despoina Televantou
Corrigendum to “Epstein–Barr-virus-positive large B-cell lymphoma associated with breast implants: an analysis of eight patients suggesting a possible pathogenetic relationship.” [Modern Pathology 34 (2021) 2154–2167, (S0893395222003763), (10.1038/s41379-021-00863-1)]2023
Dr Ugo Offor
Dr Milos Ognjanovic
Dr Gareth Parry
Abbas Khushnood
Professor Andrew Gennery
et al.
Immunology of THymectomy And childhood CArdiac transplant (ITHACA): protocol for a UK-wide prospective observational cohort study to identify immunological risk factors of post-transplant lymphoproliferative disease (PTLD) in thymectomised children2023
Dr Christopher Bacon
Dr Simon Bomken
Improving outcomes of childhood and young adult non-Hodgkin lymphoma (NHL); twenty-five years of research and collaboration within the framework of the European Intergroup for Childhood Non-Hodgkin Lymphoma (EICNHL) 2023
Dr Christopher Bacon
Dr Christopher Carey
Lymphoma triage from H&E using AI for improved clinical management2023
Dr Alex Blain
Dr Christopher Bacon
Professor Vikki Rand
Professor Matthew Collin
Dr Christopher Carey
et al.
Spatial and molecular profiling of the mononuclear phagocyte network in classic Hodgkin lymphoma2023
Dr Ugo Offor
Professor Andrew Filby
Dr Milos Ognjanovic
Dr Gareth Parry
Abbas Khushnood
et al.
Defining the systemic immune landscape in children at an increased risk of posttransplant lymphoproliferative disease: The immunology of thymectomy and childhood cardiac transplant (ITHACA) study.2022
Dr Alex Newman
Dr Masood Zaka
Dr Peixun Zhou
Dr Alex Blain
Dr Amy Erhorn
et al.
Genomic abnormalities of TP53 define distinct risk groups of paediatric B-cell non-Hodgkin lymphoma2022
Dr Simon Bomken
Dr Amir Enshaei
Dr Ed Schwalbe
Dr Aneta Mikulasova
Dr Masood Zaka
et al.
Molecular characterisation and clinical outcome of B-cell precursor acute lymphoblastic leukaemia with IG-MYC rearrangement2022
Dr Christopher Bacon
Genomic landscape of Epstein–Barr virus-positive extranodal marginal zone lymphomas of mucosa-associated lymphoid tissue2021
Dr Christopher Bacon
Molecular features of non-anaplastic peripheral T-cell lymphoma in children and adolescents2021
Dr Christopher Bacon
Dr George Petrides
Dr Nicola Leech
Dr Fiona Jenkinson
Professor Ruth Plummer
et al.
A case of malignant hyperlactaemic acidosis appearing on treatment with the mono-carboxylase transporter 1 inhibitor AZD3965.2020
Dr Christopher Bacon
Joseph O'Donoghue
Commentary on: Breast Implant-Associated Bilateral B-Cell Lymphoma2020
Dr Jarmila Spegarova
Dr Karin Engelhardt
Dr Helen Griffin
Dr Aneta Mikulasova
Dr Meghan Acres
et al.
Germline TET2 loss-of-function causes childhood immunodeficiency and lymphoma2020
Dr Ugo Offor
Dr Sujith Samarasinghe
Dr Kevin Windebank
Professor Mary Slatter
Professor Andrew Gennery
et al.
HSCT provides effective treatment for lymphoproliferative disorders in children with primary immunodeficiency2020
Dr Ugo Offor
Dr Christopher Bacon
Dr Jessica Roberts
Jason Powell
Dr Malcolm Brodlie
et al.
Transplantation For Congenital Heart Disease Is Associated With An Increased Risk Of Epstein-Barr Virus-Related Post-Transplant Lymphoproliferative Disorder In Children2020
Alex Newman
Dr Masood Zaka
Dr Peixun Zhou
Dr Amy Erhorn
Amy Barnard
et al.
Biallelic Inactivation of TP53 is Associated with an Increased Risk of Relapse in Paediatric B-Cell Non-Hodgkin Lymphoma(B-NHL)2019
Professor Mary Slatter
Dr Leigh McDonald
Dr Christopher Bacon
Dr Joaquim Majo
Professor Andrew Gennery
et al.
Late relapse of primary hemophagocytic lymphohistiocytosis after hematopoietic stem cell transplantation: a consequence of low-level chimerism from a carrier donor?2019
Dr Peixun Zhou
Dr Alex Blain
Alex Newman
Dr Masood Zaka
Dr Ugo Offor
et al.
Sporadic and endemic Burkitt lymphoma have frequent FOXO1 mutations but distinct hotspots in the AKT recognition motif2019
Dr Peixun Zhou
Dr Amir Enshaei
Alex Newman
Dr Amy Erhorn
Amy Barnard
et al.
A genomic classification model enables risk stratification of paediatric endemic Burkitt lymphoma2018
Dr Peixun Zhou
Dr Amir Enshaei
Alex Newman
Dr Amy Erhorn
Amy Barnard
et al.
A Genomic Classification Model Enables Risk Stratification of Paediatric Endemic Burkitt Lymphona in Malawi2018
Dr Ugo Offor
Dr Christopher Bacon
Professor Andrew Gennery
Dr Simon Bomken
An increased risk of post-transplant lymphoproliferative disorder in children after cardiac transplantation for congenital heart disease2018
Dr Christopher Bacon
Dr Mario Abinun
Biallelic RIPK1 mutations in humans cause severe immunodeficiency, arthritis, and intestinal inflammation2018
Alex Newman
Dr Masood Zaka
Dr Peixun Zhou
Dr Amy Erhorn
Dr Rachel Crossland
et al.
Biallelic inactivation of TP53 is associated with an increased risk of relapse in paediatric B-cell non-Hodgkin lymphoma (B-NHL)2018
Dr Ugo Offor
Dr Christopher Bacon
Professor Andrew Gennery
Dr Simon Bomken
Cardiac transplantation for congenital heart disease is associated with an increased risk of post-transplant lymphoproliferative disorder (PTLD) in children: a single centre experience2018
Dr Simon Bomken
Dr Christopher Bacon
Professor Andrew Gennery
Current Understanding and Future Research Priorities in Malignancy Associated With Inborn Errors of Immunity and DNA Repair Disorders: The Perspective of an Interdisciplinary Working Group2018
Alex Newman
Dr Peixun Zhou
Dr Masood Zaka
Professor Christine Harrison FRCPath FMedSci
Dr Simon Bomken
et al.
Genomic landscape of adult and paediatric B-cell Non-Hodgkin lymphoma2018
Dr Masood Zaka
Dr Rachel Crossland
Amy Barnard
Sara Wilkinson
Dr Simon Bomken
et al.
Integrated analysis of the genomic and microRNA landscapes identifies dysregulated pathways associated with relapsed paediatric B-cell Non-Hodgkin lymphoma2018
Dr Peixun Zhou
Alex Newman
Filbert Adlar
Casey Broadbent
Dr Alison Blain
et al.
Investigation of FOXO1 mutations in paediatric endemic and sporadic Burkitt lymphoma2018
Dr Christopher Bacon
Dr Mario Abinun
Professor Andrew Cant
Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study2017
Dr Paul Milne
Dr Venetia Bigley
Dr Christopher Bacon
Dr Naomi McGovern
Dr Simon Bomken
et al.
Hematopoietic origin of Langerhans cell histiocytosis and Erdheim Chester disease in adults2017
Dr Richard Noble
Dr Natalie Bell
Dr Helen Blair
Huw Thomas
Nicole Phillips
et al.
Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and burkitt lymphoma2017
Dr Christopher Bacon
Professor Andrew Cant
Activated PI3-kinase Delta Syndrome (APDS): Genetics, Immunodeficiency, Diagnosis and Related Pathology2016
Dr Jill Hunter
Dr Jacqueline Butterworth
Helene Sellier
Huw Thomas
Dr Christopher Bacon
et al.
The NF-κB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma2016
Dr Mark Wade
Dr Nicola Sunter
Dr Sarah Fordham
Anna Long
Dino Mašić
et al.
c-MYC is a radiosensitive locus in human breast cells2015
Dr Julian Thomas
Dr Christopher Bacon
Professor Andrew Cant
Professor Sophie Hambleton
A new case of Fas-associated death domain protein deficiency and update on treatment outcomes2015
Dr Christopher Bacon
Dr Mario Abinun
Professor Andrew Cant
Activated PI3-Kinase Delta Syndrome: Clinical, Radiological And Laboratory Features Of A Large Cohort2015
Dr Rachel Crossland
Dr Kile Green
Dr Christopher Bacon
Dr Vikki Rand
Direct digital profiling of multiplexed mRNA expression from degraded formalin fixed paraffin embedded aggressive paediatric B-cell lymphoma tumour tissue2015
Dr Peixun Zhou
Alex Newman
Dr Amy Erhorn
Dr Christopher Bacon
Professor Simon Bailey
et al.
Investigation of prognostic markers in endemic Burkitt lymphoma2015
Dr Paul Milne
Professor Matthew Collin
Dr Venetia Bigley
Dr Christopher Bacon
Dr Naomi McGovern
et al.
Mapping the BRAFV600E Hematopoietic Clone of Adult Multi-System Langerhans Cell Histiocytosis2015
Dr Christopher Carey
Dr Rachel Crossland
Dr Christopher Bacon
Dr Vikki Rand
Molecular Classification of MYC-Driven B-Cell Lymphomas by Targeted Gene Expression Profiling of Fixed Biopsy Specimens2015
Dr Michael Mather
Hannah Hayhurst
Dr Christopher Bacon
Dr Theresa Cole
Professor Andrew Gennery
et al.
Mutation of TNFRSF13B in a child with 22q11 deletion syndrome associated with granulomatous lymphoproliferation2015
Dr Natalie Bell
Dr Helen Blair
Lisa Price
Dr Katrina Wood
Professor Hermann Josef Vormoor
et al.
Patient-derived xenograft and in vivo bioluminescent modelling of B-cell NHL2015
Dr Britta Vormoor
Henrike Knizia
Michael Batey
Dr Ian Wilson
Dr Petra Dildey
et al.
Development of a Preclinical Orthotopic Xenograft Model of Ewing Sarcoma and Other Human Malignant Bone Disease Using Advanced In Vivo Imaging2014
Dr Natalie Bell
Dr Helen Blair
Professor Hermann Josef Vormoor
Dr Christopher Bacon
Dr Vikki Rand
et al.
Development of in Vivo Models of Paediatric Burkitt Lymphoma Allowing Therapeutic Target Analysis and Drug Testing2014
Dr Xiao Wang
Dr Christopher Bacon
Alison Long
Sarah Pagan
Professor Matthew Collin
et al.
Factor XIIIa identifies macrophages and cells of mesenchymal origin in the human skin2014
Dr Christopher Bacon
Gamma Heavy Chain Disease Lacks the MYD88 L265p Mutation Associated with Lymphoplasmacytic Lymphoma2014
Dr Christopher Bacon
Gamma Heavy Chain Disease Lacks the MYD88 L265P Mutation Associated with Lymphoplasmacytic Lymphoma2014
Dr Rachel Crossland
Dr Tryfonia Mainou-Fowler
Dr Michal Sieniawski
Dr Christopher Bacon
Dr Vikki Rand
et al.
High BACH2 gene Expression Is an Indicator of Poor Prognosis in Adult Diffuse Large B-Cell Lymphoma Treated with R-CHOP2014
Dr Lisa Turnbull
Dr David Bourn
Dr Christopher Bacon
Dr Michael Wright
Dr Mario Abinun
et al.
Phenotypic Variations of Cartilage Hair Hypoplasia: Granulomatous Skin Inflammation and Severe T Cell Immunodeficiency as Initial Clinical Presentation in Otherwise Well Child with Short Stature2014
Dr Christopher Bacon
Professor Andrew Cant
The Clinical Manifestations, Management and Outcomes of Activated PI3K-Delta Syndrome (APDS) in UK and Ireland Cohort2014
Dr Rachel Dickinson
Paul Milne
Dr Laura Jardine
Dr Naomi McGovern
Dr Sharon Cookson
et al.
The evolution of cellular deficiency in GATA2 mutation2014
Dr Christopher Bacon
Sarah Wilkinson
Dr Gavin Spickett
Dr Helen Lucraft
Professor Graham Jackson
et al.
Epstein-Barr virus-independent diffuse large B-cell lymphoma in DNA ligase 4 deficiency2013
Dr Maria Lastowska
Hani Al-Afghani
Haya AL-Balool
Harsh SHETH
Dr Jonathan Coxhead
et al.
Identification of a neuronal transcription factor network involved in medulloblastoma development2013
Dr Christopher Bacon
Indolent T-cell lymphoproliferative disease of the gastrointestinal tract2013
Dr Simon Bomken
Dr Lars Buechler
Dr Klaus Rehe
Dr Frida Ponthan
Dr Alex Elder
et al.
Lentiviral marking of patient-derived acute lymphoblastic leukaemic cells allows in vivo tracking of disease progression2013
Dr Christopher Bacon
Gamma Heavy-chain Disease: Defining the Spectrum of Associated Lymphoproliferative Disorders Through Analysis of 13 Cases2012
Dr Lisa Turnbull
Dr David Bourn
Dr Michael Wright
Dr Christopher Bacon
Dr Mario Abinun
et al.
Granulomatous inflammation at presentation of severe T cell immunodeficiency due to RMRP mutation (cartilage-hair hypoplasis)2012
Sarah Wilkinson
Amy Bradburn
Professor Simon Bailey
Dr Christopher Bacon
Dr Vikki Rand
et al.
High-resolution genome-wide analysis of endemic Burkitt Lymphoma using DNA extracted from fine-needle aspirates preserved at ambient temperature2012
Professor Sophie Hambleton
Dr Venetia Bigley
Professor Muzlifah Haniffa
Dr Christopher Bacon
Professor Andrew Cant
et al.
IRF8 Mutations and Human Dendritic-Cell Immunodeficiency2011
Dr Christopher Bacon
BIOMED-2 PCR assays for IGK gene rearrangements are essential for B-cell clonality analysis in follicular lymphoma2011
Dr Christopher Bacon
Cyclin D1 positive diffuse large B-cell lymphoma is a post-germinal center-type lymphoma without alterations in the CCND1 gene locus2011
Dr Christopher Bacon
Cytogenetically complex SEC31A-ALK fusions are recurrent in ALK-positive large B-cell lymphomas2011
Dr Christopher Bacon
EBV-Positive Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue in the Post-Transplant Setting: A Distinct Type of Monomorphic Post-Transplant Lymphoproliferative Disorder?2011
Dr Christopher Bacon
EBV-Positive Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue in the Post-Transplant Setting: A Distinct Type of Monomorphic Post-Transplant Lymphoproliferative Disorder?2011
Dr Christopher Bacon
EBV-Positive Extranodal Marginal Zone Lymphoma of Mucosa-associated Lymphoid Tissue in the Posttransplant Setting: A Distinct Type of Posttransplant Lymphoproliferative Disorder?2011
Dr Katherine Sturgess
Professor Mary Slatter
Dr Venetia Bigley
Professor Muzlifah Haniffa
Dr Xiao Wang
et al.
Reduced Intensity Hematopoietic Stem Cell Transplant Rescues Immune Function and Corrects Pulmonary Alveolar Proteinosis in DCML Deficiency/GATA 2 Mutation2011
Dr Christopher Bacon
Continual monitoring of intraepithelial lymphocyte immunophenotype and clonality is more important than snapshot analysis in the surveillance of refractory coeliac disease2010
Henrike Knizia
Michael Batey
Gilberto de Almeida
Dr Ross Maxwell
Dr Petra Dildey
et al.
Development of an orthotopic model for human malignant bone diseases in immunocompromised NOD.Cg-PrkdcscidIl2rgtmlwjl/szj (NSG) mice2010
Dr Christopher Bacon
Extranodal lymphoma2010
Dr Christopher Bacon
Primary effusion lymphoma: Genomic profiling revealed amplification of SELPLG and CORO1C encoding for proteins important for cell migration2010
Professor James Allan
Dr Nicola Sunter
Dr Andrew Hall
Dr Christopher Bacon
Jonathan Pointon
et al.
Variant IRF4/MUM1 associates with CD38 status and treatment-free survival in chronic lymphocytic leukaemia2010
Dr Christopher Bacon
Dr Ki Pang
Professor Andrew Cant
Professor Sophie Hambleton
Whole-exome-sequencing-based discovery of human FADD deficiency2010
Dr Christopher Bacon
A20 deletion is associated with copy number gain at the TNFA/B/C locus and occurs preferentially in translocation-negative MALT lymphoma of the ocular adnexa and salivary glands2009
Dr Christopher Bacon
Genomic Profiling of Pediatric ALK-Positive Anaplastic Large Cell Lymphoma: A Children's Cancer and Leukaemia Group Study2009
Yan Huang
Dr Christopher Bacon
Immunophenotype and Clonality of Intraepithelial Lymphocytes: Continual Monitoring is More Important Than Snapshot Analysis in the Surveillance of Refractory Coeliac Disease2009
Dr Christopher Bacon
Most primary adrenal lymphomas are diffuse large B-cell lymphomas with non-germinal center B-cell phenotype, BCL6 gene rearrangement and poor prognosis2009
Dr Christopher Bacon
Primary follicular lymphoma of the thyroid gland2009
Dr Christopher Bacon
The Lymphoma-associated Fusion Tyrosine Kinase ITK-SYK Requires Pleckstrin Homology Domain-mediated Membrane Localization for Activation and Cellular Transformation2009
Dr Christopher Bacon
FOXP1 abnormalities in lymphoma: translocation breakpoint mapping reveals insights into deregulated transcriptional control2008
Dr Christopher Bacon
Chromosomal translocations involving BCL6 in MALT lymphoma2008
Dr Christopher Bacon
Cyclin D1 – positive diffuse large B cell lymphoma2008
Dr Christopher Bacon
Mantle cell lymphoma with aberrant expression of CD102008
Dr Christopher Bacon
Peripheral T cell lymphoma with a follicular growth pattern: derivation from follicular helper T (TFH) cells and relationship to angioimmunoblastic T cell lymphoma2008
Dr Christopher Bacon
Translocations Involving the Immunoglobulin Heavy Chain Gene Locus Predict Better Survival in Gastric Diffuse Large B-Cell Lymphoma2008