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Browsing publications by Dr Karen Wallace.

Newcastle AuthorsTitleYearFull text
Dr Emma Fairhall
Dr Michelle Charles
Dr Phillip Probert
Dr Karen Wallace
Jen Gibb
et al.
Pancreatic B-13 Cell Trans-Differentiation to Hepatocytes Is Dependent on Epigenetic-Regulated Changes in Gene Expression2016
Dr Phillip Probert
Dr Stephanie Meyer
Fouzeyyah Alsaeedi
Andrew Axon
Dr Emma Fairhall
et al.
An expandable donor-free supply of functional hepatocytes for toxicology2015
Dr Emma Fairhall
Dr Karen Wallace
Professor Matthew Wright
Co-culture of B-13 hepatocyte progenitors with liver myofibroblasts promotes progenitor WNT signalling repression in response to glucocorticoids and enhances their transdifferentiation towards hepatocyte-like cells2014
Dr Michelle Charles
Dr Karen Wallace
Dr Phillip Probert
Professor Fiona Oakley
Professor Matthew Wright
et al.
THE glucocorticoid-dependent conversion of the B-13 progenitor cell into hepatocyte-like (B-13/H) cells is dependent on a short exposure to glucocorticoid and epigenetic alterations2014
Dr Emma Fairhall
Dr Karen Wallace
Steven White
Professor James Shaw
Professor Alastair Burt
et al.
Adult human exocrine pancreas differentiation to hepatocytes – potential source of a human hepatocyte progenitor for use in toxicology research2013
Dr Emma Fairhall
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Dr Karen Wallace
Professor Matthew Wright
et al.
The Hepatic Progenitor B-13 Cell Line Engrafts into the Mouse Liver and Transdifferentiates in Vivo2013
Emma Fairhall
Dr Karen Wallace
Myofibroblasts modulate the trans-differentiation of hepatic progenitor cells in vitro2011
Dr Karen Wallace
Professor James Shaw
Professor Alastair Burt
Professor Matthew Wright
Prolonged glucocorticoid exposure results in the appearance of hepatocytes in the adult pancreas2011
Dr Karen Wallace
QUAN LONG
Dr Emma Fairhall
Professor Matthew Wright
Serine/threonine protein kinase SGK1 in glucocorticoid-dependent transdifferentiation of pancreatic acinar cells to hepatocytes2011
Dr Karen Wallace
Emma Fairhall
Professor Matthew Wright
Serum- and glucorticoid-induced kinase 1 (SGK1) plays a key role in the glucocorticoid dependent trans-differentiation of a pancreatic progenitor cell to hepatocytes2011
Dr Karen Wallace
Dr Emma Fairhall
Professor Matthew Wright
AR42J-B-13 cell: An expandable progenitor to generate an unlimited supply of functional hepatocytes2010
Dr Karen Wallace
Professor Matthew Wright
Corrigendum to "Antibody-targeted myofibroblast apoptosis reduces fibrosis during sustained liver injury" [J Hepatol 49 (2008) 88-98] (DOI:10.1016/j.jhep.2008.01.032)2010
Dr Karen Wallace
Emeritus Professor Paul Flecknell
Professor Alastair Burt
Professor Matthew Wright
Disrupted Pancreatic Exocrine Differentiation and Malabsorption in Response to Chronic Elevated Systemic Glucocorticoid2010
Dr Karen Wallace
Dr Carlyn Marek
Professor Matthew Wright
Glucocorticoid-dependent transdifferentiation of pancreatic progenitor cells into hepatocytes is dependent on transient suppression of WNT signalling2010
Professor Matthew Wright
Dr Karen Wallace
Professor James Shaw
Professor Alastair Burt
Steven White
et al.
Long term glucocorticoid therapy leads to pancreatic acinar trans-differentiation into hepatocyte-like cells2010
Dr Karen Wallace
Dr David Cowie
Stephen Hill
Andy Axon
Steven White
et al.
The PXR is a drug target for chronic inflammatory liver disease2010
Dr Karen Wallace
Professor James Shaw
Professor Alastair Burt
Professor Matthew Wright
Chronic Elevated Systemic Glucocorticocoid Results in Widespread Pancreatic-Hepatic Trans-Differentiation In Vivo2009
Dr Karen Wallace
Dr Carlyn Marek
Professor Matthew Wright
Exocrine pancreas trans-differentiation to hepatocytes-A physiological response to elevated glucocorticoid in vivo2009
Dr Roben Gieling
Dr Karen Wallace
Interleukin-1 participates in the progression from liver injury to fibrosis2009
Dr Carlyn Marek
Dr Karen Wallace
Professor Matthew Wright
Low affinity glucocorticoid binding site ligands as potential anti-fibrogenics2009
Dr Karen Wallace
Dr Carlyn Marek
Professor Matthew Wright
The Trans-Differentiation of Pancreatic Acinar Cells into Hepatocytes is Mediated by a Suppression of WNT Signalling Activity2009
Dr Karen Wallace
Professor Matthew Wright
Antibody-targeted myofibroblast apoptosis reduces fibrosis during sustained liver injury2008
Dr Andrew Douglass
Dr Karen Wallace
Professor Matthew Wright
C1-3 recombinant antibody targeting myofibroblasts - Specific apoptosis reverses fibrosis in a sustained injury mouse model2008
Dr Karen Wallace
Professor Alastair Burt
Professor Matthew Wright
Liver fibrosis2008
Dr Martha Watson
Dr Karen Wallace
Dr Roben Gieling
Professor Derek Manas
Professor Derek Mann
et al.
NF-κB is a critical regulator of the survival of rodent and human hepatic myofibroblasts2008
Dr Karen Wallace
Dr David Cowie
Dr Carlyn Marek
Professor Derek Mann
Professor Matthew Wright
et al.
PXR activation reduces hepatic TNF-alpha levels - A mechanism for inhibiting liver fibrosis2008
Dr Karen Wallace
Professor Muzlifah Haniffa
Professor Matthew Collin
Professor Matthew Wright
Skin Derived Fibroblasts Can Differentiate Into Hepatocyte-Like Cells2008
Dr Karen Wallace
Professor Matthew Wright
Targeting liver myofibroblasts: a novel approach in anti-fibrogenic therapy2008
Dr Andrew Douglass
Dr Karen Wallace
Professor Matthew Wright
A human recombinant antibody for targeting anti-fibrogenic therapeutics to myofibroblasts in vivo2007
Dr Carlyn Marek
Dr Karen Wallace
Professor Matthew Wright
Expression of CYP2S1 in human hepatic stellate cells2007