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Browsing publications by Dr Ed Schwalbe.

Newcastle AuthorsTitleYearFull text
Dr Claire Keeling
Dr Jack Goddard
Dr Ed Schwalbe
Professor Simon Bailey
Dr Debbie Hicks
et al.
The clinical significance of sub-total surgical resection in childhood medulloblastoma: a multi-cohort analysis of 1100 patients2024
Dr Jack Goddard
Jemma Castle
Emily Southworth
Anya Fletcher
Dr Stephen Crosier
et al.
Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification2023
Wen Hao
Professor Deborah Tweddle
Dr Ed Schwalbe
Dr Gordon Strathdee
Genome wide DNA methylation analysis identifies novel molecular subgroups and predicts survival in neuroblastoma2022
Dr John Perry
Dr Ed Schwalbe
A chromatographic approach to distinguish Gram-positive from Gram-negative bacteria using exogenous volatile organic compound metabolites2017
Dr Ed Schwalbe
Dr Debbie Hicks
Professor Steven Clifford
Health-Related Quality of Life (HRQoL) in HIT-SIOP-PNET4 trial survivors: differences between medulloblastoma molecular subgroups2016
Dr Debbie Hicks
Dr Ed Schwalbe
Dr Stephen Crosier
Professor Simon Bailey
Dr Daniel Williamson
et al.
Identification of medulloblastoma molecular subgroups using metabolite profiles2016
Dr Janet Lindsey
Dr Rebecca Hill
Dr Ed Schwalbe
Dr Christopher Howell
Dr Reza Rafiee
et al.
Molecular and Prognostic Heterogeneity within MYC and MYCN Amplified Medulloblastomas2016
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Reza Rafiee
Dr Matthew Bashton
Dr Amir Enshaei
et al.
Routine Diagnostic Medulloblastoma Subgrouping Using Low-Cost, Low-Input DNA Methylomics: Application to Trials Cohorts Previously Refractory-to-Analysis2016
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Reza Rafiee
Dr Matthew Bashton
Dr Amir Enshaei
et al.
Routine molecular subgrouping of medulloblastoma: Bridging the divide between research and the clinic using low-cost, mass spectrometry-based DNA methylomics2016
Dr Debbie Hicks
Dr Reza Rafiee
Dr Ed Schwalbe
Dr Christopher Howell
Dr Janet Lindsey
et al.
Subgroup-Directed Stratification of Risk in Infant Medulloblastoma2016
Professor Steven Clifford
Dr Ed Schwalbe
Dr Debbie Hicks
Kieran O'Toole
Sarah Nicholson
et al.
Biomarker-driven stratification of disease-risk in non-metastatic medulloblastoma: Results from the multi-center HIT-SIOP-PNET4 clinical trial2015
Dr Janet Lindsey
Dr Ed Schwalbe
Matthew Selby
Dr James Hayden
Dr Daniel Williamson
et al.
Cross-species epigenetics identifies a critical role for VAV1 in SHH subgroup medulloblastoma maintenance2015
Dr Al Gabriel
Fadhel Alsaid Naji
Dr Ed Schwalbe
Dr Sirintra Nakjang
Dr Simon Cockell
et al.
Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia2015
Dr Janet Lindsey
Dr Ed Schwalbe
Sandeep Potluri
Professor Simon Bailey
Dr Daniel Williamson
et al.
TERT promoter mutation and aberrant hypermethylation are associated with elevated expression in medulloblastoma and characterise the majority of non-infant SHH subgroup tumours2014
Dr Janet Lindsey
Dr Ed Schwalbe
Dr James Hayden
Professor David Ellison
Dr Daniel Williamson
et al.
Cross-Species Epigenetics Identifies a Critial Role for VAV1 in the Maintenance of Sonic Hedgehog Subgroup Medulloblastomas2014
Dr Rebecca Hill
Dr Janet Lindsey
Dr Ed Schwalbe
Dr Daniel Williamson
Dr Sarra Ryan
et al.
MYC and TP53 defects emerge and interact at medulloblastoma relapse, define rapidly progressive disease and can be targeted therapeutically2014
Dr Rebecca Hill
Dr Janet Lindsey
Dr Ed Schwalbe
Dr Karen Barker
Dr Daniel Williamson
et al.
MYC and TP53 defects interact at medulloblastoma relapse to define rapidly progressive disease and can be targeted therapeutically2014
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Reza Rafiee
Dr Amir Enshaei
Sandeep Potluri
et al.
Routine molecular subgrouping of medulloblastoma: Bridging the divide between research and the clinic using low-cost DNA methylomics2014
Dr Ed Schwalbe
Dr James Hayden
Dr Janet Lindsey
Dr Rebecca Hill
Sarah Nicholson
et al.
Histologically defined central nervous system primitive neuro-ectodermal tumours (CNS-PNETs) display heterogeneous DNA methylation profiles and show relationships to other paediatric brain tumour types2013
Dr Peter Carey
Claire Schwab
Dr Lucy Chilton
Dr Ed Schwalbe
Professor Roderick Skinner
et al.
Treating childhood acute lymphoblastic leukemia in Malawi2013
Dr Ed Schwalbe
Dr Janet Lindsey
Dr Daniel Williamson
Kieran O'Toole
Dr Meryl Lusher
et al.
Epigenetic sub-classification and risk-stratification of medulloblastoma using DNA methylomics2012
Dr Ed Schwalbe
Professor Steven Clifford
Supratentorial and spinal pediatric ependymomas display a hypermethylated phenotype which includes the loss of tumor suppressor genes involved in the control of cell growth and death2012
Dr Ed Schwalbe
Professor Steven Clifford
Methylator phenotype of malignant germ cell tumours in children identifies strong candidates for chemotherapy resistance2011
Dr Ed Schwalbe
Dr Janet Lindsey
Debbie Straughton
Mike Cole
Dr Hisham Megahed
et al.
Rapid Diagnosis of Medulloblastoma Molecular Subgroups2011
Dr Janet Lindsey
Dr Rebecca Hill
Dr Hisham Megahed
Dr Meryl Lusher
Dr Ed Schwalbe
et al.
TP53 Mutations in Favorable-Risk Wnt/Wingless-Subtype Medulloblastomas2011
Dr Ed Schwalbe
Professor Steven Clifford
Dr Richard Gilbertson
Characteristic Genomic Imbalances in Paediatric Ependyoma; The Importance of Chromosome 1Q Gain2010
Dr Ed Schwalbe
Dr Janet Lindsey
Dr Meryl Lusher
Kieran O'Toole
Sarah Nicholson
et al.
DNA methylomics identifies clinically significant epigenetic subgroups of medulloblastoma2010
Dr James Hayden
Dr Matthew Allen
Dr Sarra Ryan
Sarah Nicholson
Dr Ed Schwalbe
et al.
Molecular Mechanisms in Supratentorial CNS-PNET development2010