Browsing publications by Professor Martin Noble

Newcastle AuthorsTitleYear
Dr Benoit Carbain
Dr Allyson Campbell
Dr Celine Cano
Professor Jane Endicott
Professor Bernard Golding
et al.
8-Substituted O-6-Cyclohexylmethylguanine CDK2 Inhibitors: Using Structure-Based Inhibitor Design to Optimize an Alternative Binding Mode2014
Dr Alison Hole
Dr Sonja Baumli
Professor Jane Endicott
Professor Martin Noble
Comparative Structural and Functional Studies of 4-(Thiazol-5-yl)-2-(phenylamino)pyrimidine-5-carbonitrile CDK9 Inhibitors Suggest the Basis for Isotype Selectivity2013
Professor Jane Endicott
Professor Martin Noble
Structural characterization of the cyclin-dependent protein kinase family2013
Professor Martin Noble
Professor Jane Endicott
Substituted 4-(Thiazol-5-yl)-2-(phenylamino)pyrimidines Are Highly Active CDK9 Inhibitors: Synthesis, X-ray Crystal Structures, Structure-Activity Relationship, and Anticancer Activities2013
Professor Jane Endicott
Professor Martin Noble
The structure of an MDM2-Nutlin-3a complex solved by the use of a validated MDM2 surface-entropy reduction mutant2013
Professor Martin Noble
Generation of protein lattices by fusing proteins with matching rotational symmetry2012
Professor Martin Noble
Professor Jane Endicott
Structural and functional characterization of Rpn12 identifies residues required for Rpn10 proteasome incorporation2012
Dr Sonja Baumli
Dr Alison Hole
Professor Martin Noble
Professor Jane Endicott
The CDK9 C-helix Exhibits Conformational Plasticity That May Explain the Selectivity of CAN5082012
Dr Sonja Baumli
Dr Alison Hole
Lan-zhen Wang
Professor Martin Noble
Professor Jane Endicott
et al.
The CDK9 Tail Determines the Reaction Pathway of Positive Transcription Elongation Factor b2012
Professor Jane Endicott
Professor Martin Noble
The Structural Basis for Control of Eukaryotic Protein Kinases2012
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