Browsing publications by Dr Ian Hardcastle

Newcastle AuthorsTitleYear
Honorine Lebraud
Dr Celine Cano
Dr Benoit Carbain
Dr Ian Hardcastle
Dr Ross Harrington
et al.		Trifluoroethanol solvent facilitates selective N-7 methylation of purines2013
Dr Kelly Coffey
Dr Timothy Blackburn
Susan Cook
Professor Bernard Golding
Professor Roger Griffin
et al.		Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer2012
Thomas Rennison
Faye Craven
Professor Bernard Golding
Professor Roger Griffin
Dr Karen Haggerty
et al.		Potent enantioselective inhibition of DNA-dependent protein kinase (DNA-PK) by atropisomeric chromenone derivatives2012
Dr Kate Smith
Professor Bernard Golding
Elizabeth Griffin
Professor Roger Griffin
Dr Ian Hardcastle
et al.		DNA-dependent protein kinase (DNA-PK) inhibitors: Structure–activity relationships for O-alkoxyphenylchromen-4-one probes of the ATP-binding domain2011
Dr Ian Hardcastle
Alex Liu
Dr Eric Valeur
Anna Watson
Shafiq Ahmed
et al.		Isoindolinone Inhibitors of the Murine Double Minute 2 (MDM2)-p53 Protein-Protein Interaction: Structure-ActivityStudies Leading to Improved Potency2011
Dr Karim Bennaceur
Dr Catherine Drummond
Professor Jane Endicott
Professor Bernard Golding
Professor Roger Griffin
et al.		MDM2-p53 protein-protein interaction inhibitors: A-ring substituted isoindolinones2011
Huw Thomas
Dr Celine Roche
Dr Johanne Bentley
Dr Ian Hardcastle
Professor Bernard Golding
et al.		Preclinical in vitro and in vivo evaluation of the potent and specific cyclin-dependent kinase 2 inhibitor NU6102 and a water soluble prodrug NU63012011
Professor Martin Noble
Dr Ian Hardcastle
Professor Jane Endicott
Understanding small-molecule binding to MDM2: Insights into structural effects of isoindolinone inhibitors from NMR spectroscopy2011
Sonsoles Rodriguez-Aristegui
Lauren Barrett
Dr Celine Cano
Dr Marine Desage-El-Murr
Professor Roger Griffin
et al.		Versatile Synthesis of Functionalised Dibenzothiophenes via Suzuki Coupling and Microwave-assisted Ring Closure2011
Dr Celine Cano
Professor Bernard Golding
Dr Karen Haggerty
Dr Ian Hardcastle
Professor Roger Griffin
et al.		Atropisomeric 8-arylchromen-4-ones exhibit enantioselective inhibition of the DNA-dependent protein kinase (DNA-PK)2010
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