Browsing publications by Dr David Samuels

Newcastle AuthorsTitleYear
Christoph Freyer
Dr Lynsey Cree
Dr Vasileios Floros
Dr David Samuels
Professor Patrick Chinnery
et al.
Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission2012
Dr Brendan Payne
Dr Ian Wilson
Professor Rita Horvath
Dr Mauro Santibanez Koref
Dr David Samuels
et al.
Mitochondrial aging is accelerated by anti-retroviral therapy through the clonal expansion of mtDNA mutations2011
Joanna Stewart
Kamil Sitarz
Professor Rita Horvath
Dr Angela Pyle
Dr Patrick Yu Wai Man
et al.
POLG mutations cause decreased mitochondrial DNA repopulation rates following induced depletion in human fibroblasts2011
Dr Patrick Yu Wai Man
Kamil Sitarz
Dr David Samuels
Philip Griffiths
Dr Amy Reeve
et al.
OPA1 mutations cause cytochrome c oxidase deficiency due to loss of wild-type mtDNA molecules2010
Professor Patrick Chinnery
Dr David Samuels
Previous Estimates of Mitochondrial DNA Mutation Level Variance Did Not Account for Sampling Error: Comparing the mtDNA Genetic Bottleneck in Mice and Humans2010
Dr David Samuels
Professor David Burn
Professor Patrick Chinnery
Detecting new neurodegenerative disease genes: does phenotype accuracy limit the horizon?2009
Dr Lynsey Cree
Dr David Samuels
Professor Patrick Chinnery
The inheritance of pathogenic mitochondrial DNA mutations2009
Dr Hannah Elliott
Dr David Samuels
James Eden
Professor Caroline Relton
Professor Patrick Chinnery
et al.
Pathogenic Mitochondrial DNA Mutations Are Common in the General Population2008
Professor Patrick Chinnery
Dr David Samuels
Selection against Pathogenic mtDNA Mutations in a Stem Cell Population Leads to the Loss of the 3243A→G Mutation in Blood2008
Professor Patrick Chinnery
Dr David Samuels
The Distribution of Mitochondrial DNA Heteroplasmy Due to Random Genetic Drift2008
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