Dr Kappusamy Saravanan Hannah Barlow Marion Barton Professor Hilary Calvert Professor Bernard Golding et al. | Nucleoside Transport Inhibitors: Structure-Activity Relationships for Pyrimido[5,4-d]pyrimidine Derivatives That Potentiate Pemetrexed Cytotoxicity in the Presence of alpha(1)-Acid Glycoprotein | 2011 |
Dr Christopher Wong Professor Roger Griffin Dr Ian Hardcastle Dr Julian Scott Northen Lan-zhen Wang et al. | Synthesis of sulfonamide-based kinase inhibitors from sulfonates by exploiting the abrogated S(N)2 reactivity of 2,2,2-trifluoroethoxysulfonates | 2010 |
Huw Thomas Dr Kappusamy Saravanan Lan-zhen Wang Mei Lin Dr Julian Scott Northen et al. | Preclinical evaluation of a novel pyrimidopyrimidine for the prevention of nucleoside and nucleobase reversal of antifolate cytotoxicity | 2009 |
Dr Ian Hardcastle Shafiq Ahmed Helen Atkins Gillian Farnie Professor Bernard Golding et al. | Small-molecule inhibitors of the MDM2-p53 protein-protein interaction based on an isoindolinone scaffold | 2006 |
Dr Ian Hardcastle Shafiq Ahmed Professor Alan Calvert Professor Nicola Curtin Gillian Farnie et al. | Isoindolinone-based inhibitors of the MDM2-p53 protein-protein interaction | 2005 |
Dr Julian Scott Northen Emeritus Professor William Clegg Professor Nicola Curtin Professor Roger Griffin Professor Bernard Golding et al. | Controlled stepwise conversion of 2,4,6,8-tetrachloropyrimido-[5,4-d ]pyrimidine into 2,4,6,8-tetrasubstituted pyrimido[5,4-d]pyrimidines | 2002 |
Professor Alan Calvert Professor Nicola Curtin Professor Bernard Golding Professor Roger Griffin Dr Ian Hardcastle et al. | Inhibiting the MDM2-p53 interaction using low molecular weight compounds | 2001 |