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Browsing publications by Professor David Ellison.

Newcastle AuthorsTitleYearFull text
Professor Steven Clifford
Professor David Ellison
Medulloblastoma2019
Professor Simon Bailey
Professor David Ellison
Professor Steven Clifford
An Exploration of Associations between Health Related Quality of Life and Medulloblastoma Molecular Subgroup Status in Survivors from the SIOP UKCCSG PNET3 Trial2014
Dr Janet Lindsey
Dr Ed Schwalbe
Dr James Hayden
Professor David Ellison
Dr Daniel Williamson
et al.
Cross-Species Epigenetics Identifies a Critial Role for VAV1 in the Maintenance of Sonic Hedgehog Subgroup Medulloblastomas2014
Professor Simon Bailey
Professor David Ellison
Professor Steven Clifford
Improved health-related quality of life outcomes associated with SHH subgroup medulloblastoma in SIOP-UKCCSG PNET3 trial survivors2014
Dr Sarra Ryan
Dr Ed Schwalbe
Mike Cole
Yuan Lu
Dr Meryl Lusher
et al.
MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma2012
Dr Ed Schwalbe
Dr Janet Lindsey
Dr Daniel Williamson
Kieran O'Toole
Dr Meryl Lusher
et al.
Epigenetic sub-classification and risk-stratification of medulloblastoma using DNA methylomics2012
Professor Steven Clifford
Professor David Ellison
Dr Richard Gilbertson
Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas2012
Professor Steven Clifford
Professor David Ellison
Dr Richard Gilbertson
Molecular subgroups of medulloblastoma: the current consensus2012
Professor David Ellison
Dr Hisham Megahed
Dr Meryl Lusher
Dr Sarra Ryan
Professor Simon Bailey
et al.
Definition of Disease-Risk Stratification Groups in Childhood Medulloblastoma Using Combined Clinical, Pathologic, and Molecular Variables2011
Professor David Ellison
Sarah Nicholson
Professor Simon Bailey
Professor Steven Clifford
Dr Richard Gilbertson
et al.
Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups2011
Dr Ed Schwalbe
Dr Janet Lindsey
Debbie Straughton
Mike Cole
Dr Hisham Megahed
et al.
Rapid Diagnosis of Medulloblastoma Molecular Subgroups2011
Dr Janet Lindsey
Dr Rebecca Hill
Dr Hisham Megahed
Dr Meryl Lusher
Dr Ed Schwalbe
et al.
TP53 Mutations in Favorable-Risk Wnt/Wingless-Subtype Medulloblastomas2011
Professor David Ellison
Dr Hisham Megahed
Dr Sarra Ryan
Dr Meryl Lusher
Sarah Nicholson
et al.
Clinical, pathological, and molecular variables define risk-stratification groups in childhood medulloblastoma2010
Dr Vikki Rand
Professor David Ellison
Dr Richard Gilbertson
Cross-species genomics matches driver mutations and cell compartments to model ependymoma2010
Dr Jun Ma
Professor Simon Bailey
Professor David Ellison
MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas2010
Professor Steven Clifford
Dr Sarra Ryan
Mike Cole
Dr Meryl Lusher
Kieran O'Toole
et al.
MYC gene family amplification and expression in childhood medulloblastoma: Biological significance and utility for high-risk disease stratification2010
Dr Janet Lindsey
Professor Steven Clifford
Professor David Ellison
Dr Richard Gilbertson
Subtypes of medulloblastoma have distinct developmental origins2010
Professor David Ellison
Professor Simon Bailey
Activation of the MAPK Pathway: A Signature Genetic Defect in Posterior Fossa Pilocytic Astrocytomas2009
Dr Sarra Ryan
Professor David Elliott
Professor David Ellison
Professor Simon Bailey
Professor Steven Clifford
et al.
Amplification and overexpression of Hsa-miR-3ob, Hsa-miR-30d and KHDRBS3 at 8q24.22-q24.23 in medulloblastoma2009
Professor Steven Clifford
Kieran O'Toole
Professor David Ellison
Chromosome 1q gain is not associated with a poor outcome in childhood medulloblastoma: requirements for the validation of potential prognostic biomarkers2009
Dr James Hayden
Professor David Ellison
Professor Simon Bailey
Professor Steven Clifford
Frequent IDH1 mutations in supratentorial primitive neuroectodermal tumors (sPNET) of adults but not children2009
Dr Helen Lucraft
Professor David Ellison
Impact of radiotherapy parameters on outcome for patients with supratentorial primitive neuro-ectodermal tumours entered into the SIOP/UKCCSG PNET 3 study2009
Professor Steven Clifford
Professor David Ellison
Kieran O'Toole
Improved Stratification of Standard Risk Medulloblastoma Patients by Clinical and Biological Prognostic Factors2009
Professor Steven Clifford
Professor David Ellison
Novel mechanisms of gene disruption at the medulloblastoma isodicentric 17p11 breakpoint2009
Jennifer Anderton
Dr Janet Lindsey
Dr Meryl Lusher
Dr Richard Gilbertson
Professor Simon Bailey
et al.
Global analysis of the medulloblastoma epigenome identifies disease-subgroup-specific inactivation of COL1A22008
Professor David Ellison
Professor Steven Clifford
Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features2008
Professor Steven Clifford
Dr Meryl Lusher
Dr Janet Lindsey
Dr Jackie Langdon
Dr Richard Gilbertson
et al.
Wnt-pathway medulloblastomas2008
Professor David Ellison
Dr Janet Lindsey
Dr Meryl Lusher
Professor Steven Clifford
Beta-catenin status predicts favorable prognosis in childhood medulloblastoma2007
Professor Steven Clifford
Yuan Lu
Dr Debbie Scott
Professor David Ellison
Chromosome 8 contains multiple independent loci involved in medulloblastoma development2007
Professor David Ellison
Dr Richard Gilbertson
Clinical and molecular characteristics of malignant transformation of low-grade glioma in children2007
Dr Janet Lindsey
Dr Meryl Lusher
Jennifer Anderton
Dr Richard Gilbertson
Professor David Ellison
et al.
Epigenetic deregulation of multiple S100 gene family members by differential hypomethylation and hypermethylation events in medulloblastoma2007
Professor Steven Clifford
Professor David Ellison
Identification of novel mechanisms for gene disruption at the medulloblastoma isochromosome breakpoint locus2007
Charles McManamy
Dr Jane Pears
Professor Steven Clifford
Professor David Ellison
Nodule formation and desmoplasia in medulloblastomas - Defining the nodular/desmoplastic variant and its biological behavior2007
Professor David Ellison
Presence of factors predictive of response to anti-EGFR therapy in pediatric high-grade gliomas2007
Professor David Ellison
Primary postoperative chemotherapy without radiotherapy for intracranial ependymoma in children: the UKCCSG/SIOP prospective study2007
Professor David Ellison
Beth Gibson
Dr Pamela Kearns
The childhood tumour and leukaemia banks - A national protocol for collecting and banking childhood cancer tissue samples for research - On behalf of the CCLG Biological Studies Steering Group2007
Professor David Ellison
Trisomy 19 ependymoma, a newly recognized genetico-histological association, including clear cell ependymoma2007
Dr Vankateswara Ramesh
Dr Anil Gholkar OBE
Professor David Ellison
Alexander disease - Ventricular garlands and abnormalities of the medulla and spinal cord2006
Olabisi Onilude
Dr Meryl Lusher
Dr Janet Lindsey
Professor Andrew Pearson
Professor David Ellison
et al.
APC and CTNNB1 mutations are rare in sporadic ependymomas2006
Professor David Ellison
Emeritus Professor David Mendelow
Cathepsin S expression: An independent prognostic factor in glioblastoma tumours - A pilot study2006
Dr Jackie Langdon
Dr Jayne Lamont
Dr Debbie Scott
Dr Nicholas Bown
Professor David Ellison
et al.
Combined genome-wide allelotyping and copy number analysis identify frequent genetic losses without copy number reduction in medulloblastoma2006
Dr Janet Lindsey
Dr Meryl Lusher
Dr Gordon Strathdee
Robert Brown
Dr Richard Gilbertson
et al.
Epigenetic inactivation of MCJ (DNAJD1) in malignant paediatric brain tumours2006
Dr Janet Lindsey
Dr Meryl Lusher
Dr Gordon Strathdee
Dr Richard Gilbertson
Professor Simon Bailey
et al.
Epigenetic inactivation of MCJ (DNAJD1) in malignant paediatric brain tumours2006
Dr Debbie Scott
Debbie Straughton
Mike Cole
Professor Simon Bailey
Professor David Ellison
et al.
Identification and analysis of tumor suppressor loci at chromosome 10q23.3-10q25.3 in medulloblastoma2006
Professor David Ellison
Identification of candidate tumor-suppressor genes on chromosome 8p in medulloblastomas by expression profiling2006
Professor Steven Clifford
Dr Meryl Lusher
Dr Janet Lindsey
Dr Jackie Langdon
Dr Richard Gilbertson
et al.
Wnt/Wingless pathway activation and chromosome 6 loss characterize a distinct molecular sub-group of medulloblastomas associated with a favorable prognosis2006
Professor David Ellison
Olabisi Onilude
Dr Janet Lindsey
Dr Meryl Lusher
Professor Andrew Pearson
et al.
β-catenin status predicts a favorable outcome in childhood medulloblastoma: the United Kingdom Children's Cancer Study Group Brain Tumour Committee2005
Dr Jayne Lamont
Professor Deborah Tweddle
Professor Andrew Pearson
Professor Steven Clifford
Professor David Ellison
et al.
A 7-year-old boy with midline cerebellar mass2005
Professor David Ellison
Dr Timothy Williams
A beta-related angiitis: primary angiitis of the central nervous system associated with cerebral amyloid angiopathy2005
David Hamilton
Dr Meryl Lusher
Dr Janet Lindsey
Professor David Ellison
Professor Steven Clifford
et al.
Epigenetic inactivation of the RASSF1A tumour suppressor gene in ependymoma2005
Professor David Ellison
Outcome for patients with metastatic (M2-3) medulloblastoma treated with SIOP/UKCCSG PNET-3 chemotherapy2005
Patrick Mitchell
Professor David Ellison
Emeritus Professor David Mendelow
Surgery for malignant gliomas: mechanistic reasoning and slippery statistics2005
Professor David Ellison
Woman aged 24 years with fourth ventricular mass2005
Helen Fernandes
Professor David Ellison
Woman aged 24 years with fourth ventricular mass2005
Professor David Ellison
Professor Andrew Pearson
Professor Steven Clifford
Dr Jayne Lamont
Charles McManamy
et al.
Combined histopathological and molecular cytogenetic stratification defines a high-risk subset of patients with medulloblastoma - A United Kingdom Children's Cancer Group Study2004
Dr Jayne Lamont
Charles McManamy
Professor Andrew Pearson
Professor Steven Clifford
Professor David Ellison
et al.
Combined histopathological and molecular cytogenetic stratification of medulloblastoma patients2004
Professor David Ellison
Genetic and expression profiles of cerebellar liponeurocytomas2004
Professor David Ellison
Genomic imbalances in high- and low-grade paediatric astrocytomas2004
Professor David Ellison
Genomic imbalances in supratentorial primitive neuroectodermal tumours (stPNETS)2004
Professor Steven Clifford
Dr Janet Lindsey
Dr Meryl Lusher
Dr Richard Gilbertson
Professor Andrew Pearson
et al.
Identification of tumour suppressor genes in childhood medulloblastoma by promoter hypermethylation profiling2004
Dr Janet Lindsey
Dr Meryl Lusher
Jennifer Anderton
Professor Simon Bailey
Dr Richard Gilbertson
et al.
Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling2004
Professor David Ellison
Dr Helen Lucraft
Dr Richard Gilbertson
Impact of radiotherapy parameters on outcome in the International Society of Paediatric Oncology/United Kingdom Children's Cancer Study Group PNET-3 study of preradiotherapy chemotherapy for M0-M1 medulloblastoma2004
Professor David Ellison
Charles McManamy
Professor Andrew Pearson
Professor Steven Clifford
The clinical utility of stratifying medulloblastomas (MBs) by a combination of detailed histopathologic evaluation and molecular cytogenetic analysis2004
Dr Janet Lindsey
Dr Meryl Lusher
Professor Andrew Pearson
Professor David Ellison
Professor Steven Clifford
et al.
Identification of tumour suppressor genes in childhood medulloblastoma by promoter hypermethylation profiling2003
Dr Debbie Scott
Dr Janet Lindsey
Dr Meryl Lusher
Professor Andrew Pearson
Professor David Ellison
et al.
Identification of tumour suppressor loci on chromosome 10q in medulloblastoma2003
Dr Jayne Lamont
Charles McManamy
Professor Andrew Pearson
Professor Steven Clifford
Professor David Ellison
et al.
Molecular cytogenetic analysis of a cohort of medulloblastomas2003
Charles McManamy
Dr Jayne Lamont
Mike Cole
Professor Andrew Pearson
Professor Steven Clifford
et al.
Morphophenotypic variation predicts clinical behavior in childhood non-desmoplastic medulloblastomas2003
Professor David Ellison
Dr Helen Lucraft
Dr Richard Gilbertson
Results of a randomized study of preradiation chemotherapy versus radiotherapy alone for nonmetastatic medulloblastoma: The International Society of Paediatric Oncology United Kingdom Children's Cancer Study Group PNET-3 study2003
Professor David Ellison
Dr Daniel Birchall
Use of serial proton magnetic resonance spectroscopy to differentiate low grade glioma from tumefactive plaque in a patient with multiple sclerosis2003
Professor David Ellison
Professor Steven Clifford
Dr Richard Gilbertson
What's new in neuro-oncology? Recent advances in medulloblastoma2003
Dr Meryl Lusher
Dr Janet Lindsey
Professor Andrew Pearson
Professor David Ellison
Professor Steven Clifford
et al.
Biallelic epigenetic inactivation of the RASSF1A tumor suppressor gene in medulloblastoma development2002
Professor David Ellison
Classifying the medulloblastoma: insights from morphology and molecular genetics2002
Dr Richard Gilbertson
Roberto Hernan
Dr Adrian Frank
Professor David Ellison
ERBB receptor signaling promotes ependymoma cell proliferation and represents a potential novel therapeutic target for this disease2002
Emeritus Professor Robert Perry
Dr David Walker
Dr Richard Gilbertson
Professor David Ellison
Genetic abnormalities detected in ependymomas by comparative genomic hybridisation2002
Emeritus Professor Robert Perry
Professor David Ellison
Genetic abnormalities detected in genomic hybridisation epenclymomas by comparative2002
Professor David Ellison
Genomic imbalances in pediatric intracranial ependymomas define clinically relevant groups2002
Dr Richard Gilbertson
Roberto Hernan
Emeritus Professor Robert Perry
Professor John Lunec
Professor Andrew Pearson
et al.
Clinical and molecular stratification of disease risk in medulloblastoma2001
Professor David Ellison
Genomic imbalances in paediatric ependymomas; A United Kingdom Childrens Cancer Study Group (UKCCSG) approved study2001
Professor David Ellison
Genomic imbalances in paediatric ependymomas; A United Kingdom Children's Cancer Study Group (UKCCSG) approved study2001
Professor David Ellison
Dr Bridget Wilkins
Lymphoma and the nervous system2001
Dr Richard Gilbertson
Professor David Ellison
Molecular stratification of disease risk in childhood medulloblastoma2001
Dr Richard Gilbertson
Roberto Hernan
Professor David Ellison
Emeritus Professor Robert Perry
Professor Andrew Pearson
et al.
Novel ErbB4 juxtamembrane splice variants and the truncated ErbB2 receptor isoform are frequently expressed in childhood medulloblastoma2001
Dr Richard Gilbertson
Roberto Hernan
Professor David Ellison
Emeritus Professor Robert Perry
Professor Andrew Pearson
et al.
Novel ERBB4 juxtamembrane splice variants are frequently expressed in childhood medulloblastoma2001
Dr David Walker
Professor David Ellison
Analysis of ependymomas using comparative genomic hybridisation2000
Professor David Ellison
Comparative genomic hybridization and histological variation in primitive neuroectodermal tumours1999
Professor David Ellison
V-H gene sequences from primary central nervous system lymphomas indicate derivation from highly mutated germinal cancer B cells with ongoing mutational activity1999
Professor David Ellison
Professor John Lunec
Dr Evelyn Jaros
Accumulation of wild-type p53 in meningiomas1995