Browsing publications by Professor Caroline Austin

Newcastle AuthorsTitleYear
Professor Caroline Austin
Salicylate, a Catalytic Inhibitor of Topoisomerase II, Inhibits DNA Cleavage and Is Selective for the alpha Isoform2014
Professor Caroline Austin
Dr Miguel Lopez-Lazaro
Alpha, beta-unsaturated lactones 2-furanone and 2-pyrone induce cellular DNA damage, formation of topoisomerase I- and II-DNA complexes and cancer cell death2013
Dr Ian Cowell
Professor Caroline Austin
Do transcription factories and TOP2B provide a recipe for chromosome translocations in therapy-related leukemia?2012
Dr Ian Cowell
Professor Caroline Austin
Mechanism of Generation of Therapy Related Leukemia in Response to Anti-Topoisomerase II Agents2012
Dr Ian Cowell
Dr Zbyslaw Sondka
Kayleigh Smith
Ka Lee
Catriona Manville
et al.
Model for MLL translocations in therapy-related leukemia involving topoisomerase II╬▓-mediated DNA strand breaks and gene proximity2012
Dr Kay Padget
Hannah Curtis
Dr Ian Cowell
Dr Zbyslaw Sondka
Dr Nick Morris
et al.
MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA2012
Professor Caroline Austin
Dr Miguel Lopez-Lazaro
The Coffee Constituent Chlorogenic Acid Induces Cellular DNA Damage and Formation of Topoisomerase I- and II-DNA Complexes in Cells2012
Pauline Heslop
Professor Caroline Austin
The Structure of DNA-Bound Human Topoisomerase II Alpha: Conformational Mechanisms for Coordinating Inter-Subunit Interactions with DNA Cleavage2012
Catriona Manville
Professor Caroline Austin
Topoisomerase II alpha sites of occupancy on human chromosome 222012
Dr Ian Cowell
Dr Michael Tilby
Professor Caroline Austin
An overview of the visualisation and quantitation of low and high MW DNA adducts using the trapped in agarose DNA immunostaining (TARDIS) assay2011
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