Browsing publications by Professor Caroline Austin

Newcastle AuthorsTitleYear
Professor Caroline Austin
A high-throughput fluorescence anisotropy-based assay for human topoisomerase II β-catalyzed ATP-dependent supercoiled DNA relaxation2014
Andy Best
Caroline Dalgliesh
Elaine Hong
Mahsa Kheirollahi Kouhestani
Yaobo Xu
et al.
Human Tra2 proteins jointly control a CHK1 splicing switch amongst alternative and constitutive target exons2014
Professor Caroline Austin
Salicylate, a Catalytic Inhibitor of Topoisomerase II, Inhibits DNA Cleavage and Is Selective for the alpha Isoform2014
Kayleigh Smith
Dr Ian Cowell
Dr Zbyslaw Sondka
Professor Caroline Austin
The Role of Topoisomerase II Beta on Breakage and Proximity of RUNX1 to Partner Alleles RUNX1T1 and EVI12014
Professor Caroline Austin
Dr Miguel Lopez-Lazaro
Alpha, beta-unsaturated lactones 2-furanone and 2-pyrone induce cellular DNA damage, formation of topoisomerase I- and II-DNA complexes and cancer cell death2013
Dr Ian Cowell
Professor Caroline Austin
Do transcription factories and TOP2B provide a recipe for chromosome translocations in therapy-related leukemia?2012
Professor Caroline Austin
Dr Miguel Lopez-Lazaro
Guanidine-reactive agent phenylglyoxal induces DNA damage and cancer cell death2012
Dr Ian Cowell
Professor Caroline Austin
Mechanism of Generation of Therapy Related Leukemia in Response to Anti-Topoisomerase II Agents2012
Dr Ian Cowell
Dr Zbyslaw Sondka
Kayleigh Smith
Ka Lee
Catriona Manville
et al.
Model for MLL translocations in therapy-related leukemia involving topoisomerase IIβ-mediated DNA strand breaks and gene proximity2012
Dr Kay Padget
Hannah Curtis
Dr Ian Cowell
Dr Zbyslaw Sondka
Dr Nick Morris
et al.
MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA2012
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