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Browsing publications by Geoffrey Taylor.

Newcastle AuthorsTitleYearFull text
Dr Laura Greaves
Marco Nooteboom
Dr Joanna Elson
Dr Helen Tuppen
Geoffrey Taylor
et al.
Clonal Expansion of Early to Mid-Life Mitochondrial DNA Point Mutations Drives Mitochondrial Dysfunction during Human Ageing2014
Dr Laura Greaves
Dr Joanna Elson
Dr John Grady
Geoffrey Taylor
Professor Robert Taylor
et al.
Comparison of Mitochondrial Mutation Spectra in Ageing Human Colonic Epithelium and Disease: Absence of Evidence for Purifying Selection in Somatic Mitochondrial DNA Point Mutations2012
Dr Patrick Yu Wai Man
Dr Gillian Borthwick
Dr Langping He
Geoffrey Taylor
Dr Laura Greaves
et al.
Somatic Mitochondrial DNA Deletions Accumulate to High Levels in Aging Human Extraocular Muscles2010
Dr Laura Greaves
Nina Beadle
Geoffrey Taylor
Dr Daniel Commane
Professor John Mathers
et al.
Quantification of mitochondrial DNA mutation load2009
Dr Amy Reeve
Geoffrey Taylor
Dr Joanna Elson
Professor Robert Taylor
Dr Christopher Morris
et al.
The low abundance of clonally expanded mitochondrial DNA point mutations in aged substantia nigra neurons2009
Geoffrey Taylor
Professor Pamela Shaw
Emeritus Professor Doug Turnbull
Professor Robert Taylor
Investigation of the mitochondrial genome in patients with atypical motor neuron disease2007
Professor Gareth Veal
Mike Cole
Geoffrey Taylor
Julie Errington
Professor Alan Boddy
et al.
Pharmacogenetics and metabolism of cyclophosphamide in paediatric cancer patients2007
Dr Christopher Morris
Geoffrey Taylor
Dr Amy Reeve
Emeritus Professor Robert Perry
Dr Evelyn Jaros
et al.
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease2006
Dr Gillian Borthwick
Professor Robert Taylor
Dr Timothy Walls
Dr Kasia Tonska
Geoffrey Taylor
et al.
Motor neuron disease in a patient with a mitochondrial tRNAlle mutation2006
Dr Debbie Pye
Dimitra-Smaragda Kyriakouli
Geoffrey Taylor
Dr Matthias Elstner
Professor Zofia Chrzanowska-Lightowlers
et al.
Production of transmitochondrial cybrids containing naturally occurring pathogenic mtDNA variants2006
Professor John Bond
Mark Barrow
Dr Sally Lynch
Merajuddin Ahmed
Geoffrey Taylor
et al.
The importance of seeking ALMS1 mutations in infants with dilated cardiomyopathy2005
Professor Robert Taylor
Dr Langping He
Dr Laura Greaves
Geoffrey Taylor
Dr Martin Barron
et al.
Mitochondrial DNA mutations in human colonic crypt stem cells2004
Professor Robert Taylor
Professor Patrick Chinnery
Geoffrey Taylor
Emeritus Professor Doug Turnbull
Genotypes from patients indicate no paternal mitochondrial DNA contribution2003
Professor Robert Taylor
Dr Martin Barron
Dr Gillian Borthwick
Professor Patrick Chinnery
Dr David Samuels
et al.
Mitochondrial DNA mutations and aging in human colonic crypts and stem cells2003
Professor Robert Taylor
Dr Martin Barron
Dr Gillian Borthwick
Professor Patrick Chinnery
Dr David Samuels
et al.
Mitochondrial DNA mutations in human colonic crypt stem cells2003
Dr Stephen Lynn
Geoffrey Taylor
Dr Theresa Wardell
Professor Patrick Chinnery
Emeritus Professor Doug Turnbull
et al.
Defining the importance of mitochondrial gene defects in maternally inherited diabetes by sequencing the entire mitochondrial genome2002
Professor Herbie Newell
Professor Alan Boddy
Geoffrey Taylor
Andrew Johnston
Professor Andrew Pearson
et al.
A phase I study of nolatrexed dihydrochloride in children with advanced cancer. A United Kingdom Children's Cancer Study Group Investigation2001
Dr Brian Moore
Geoffrey Taylor
Emeritus Professor Nicol Ferrier
Professor Jim Edwardson
Absorption of aluminium-26 in Alzheimer's disease, measured using accelerator mass spectrometry2000
Geoffrey Taylor
Professor Jim Edwardson
Dr Christopher Morris
Brain oestradiol and testosterone levels in Alzheimer's disease2000
Professor Patrick Chinnery
Geoffrey Taylor
Dr Richard Andrews
Dr Christopher Morris
Professor Robert Taylor
et al.
Mitochondrial DNA haplogroups and susceptibility to AD and dementia with Lewy bodies2000
Dr David Cottrell
Dr Emma Watson
Dr Gillian Borthwick
Dr Margaret Johnson
Geoffrey Taylor
et al.
Role of mitochondrial DNA mutations in disease and aging2000
Dr Andrew Hall
Professor John Lunec
Professor Herbie Newell
Professor Andrew Pearson
Geoffrey Taylor
et al.
Thymidylate synthase expression in nolatrexed and methotrexate-resistant human leukaemia cell lines1998
Geoffrey Taylor
Dr Christopher Morris
Emeritus Professor Robert Perry
Professor Jim Edwardson
Patricia Harrison
et al.
Iron and aluminium in relation to brain ferritin in normal individuals and Alzheimer's-disease and chronic renal-dialysis patients1992
Geoffrey Taylor
Professor Alan Calvert
ICI D1694, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo: a new agent for clinical study1991
Professor Herbie Newell
Geoffrey Taylor
Professor Alan Calvert
The biochemical pharmacology of the thymidylate synthase inhibitor, 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583)1991
Geoffrey Taylor
Professor Alan Calvert
Activity of the thymidylate synthase inhibitor 2-desamino-N-10- propargyl-5,8-dideazafolic acid and related-compounds in murine (L1210) and human (W1l2) systems in Vitro and in L1210 in Vivo1990
Geoffrey Taylor
Professor Alan Calvert
Estimation of the in vitro and in vivo inhibitory effects of antifolates upon thymidylate synthase (TS) in whole cells1989
Geoffrey Taylor
Professor Alan Calvert
Modulation of anti-metabolite effects: effects of thymidine on the efficacy of the quinazoline based thymidylate synthetase inhibitor, CB37171984
Geoffrey Taylor
Professor Alan Calvert
Plasma nucleoside and base levels following treatment with the new thymidylate synthetase inhibitor-CB-37171984
Geoffrey Taylor
Professor Alan Calvert
Methotrexate with thymidine, inosine, and allopurinol rescue - a phase-I clinical-study1981