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Browsing publications by Dr Andrew Hall.

Newcastle AuthorsTitleYearFull text
Dr Carmela Ciardullo
Dr Katarzyna Szoltysek
Dr Peixun Zhou
Dr Elaine Willmore
Dr Amir Enshaei
et al.
Low BACH2 expression predicts adverse outcome in chronic lymphocytic leukaemia2022
Dr Katarzyna Szoltysek
Dr Carmela Ciardullo
Dr Peixun Zhou
Dr Anna Walaszczyk
Dr Elaine Willmore
et al.
Dap kinase-related apoptosis-inducing protein kinase 2 (Drak2) is a key regulator and molecular marker in chronic lymphocytic leukemia2020
Dr Peixun Zhou
Dr Alex Blain
Alex Newman
Dr Masood Zaka
Dr Ugo Offor
et al.
Sporadic and endemic Burkitt lymphoma have frequent FOXO1 mutations but distinct hotspots in the AKT recognition motif2019
Dr Max Robinson
Professor Philip Sloan
Dr Andrew Hall
Training and accreditation standards for pathologists undertaking clinical trial work2019
Dr Andrew Hall
Barriers to the release of human tissue for clinical trials research in the UK: A national survey of cellular pathology laboratories on behalf of the National Cancer Research Institute's Cellular Molecular Pathology (CM-Path) initiative2018
Dr Peixun Zhou
Alex Newman
Filbert Adlar
Casey Broadbent
Dr Alison Blain
et al.
Investigation of FOXO1 mutations in paediatric endemic and sporadic Burkitt lymphoma2018
Dr Nicola Sunter
Dr Andrew Hall
Dr Tryfonia Mainou-Fowler
Professor Graham Jackson
Dr Helen Marr
et al.
Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia2017
Dr Carmela Ciardullo
Dr Elaine Willmore
Dr Amir Enshaei
Dr Peixun Zhou
Dr Vikki Rand
et al.
BACH2 and BCL6 Cooperatively Fuction as Tumour Suppressors in CLL2016
Dr Carmela Ciardullo
Dr Elaine Willmore
Dr Peixun Zhou
Dr Vikki Rand
Professor Christine Harrison FRCPath FMedSci
et al.
Impact of the apoptotic regulator DRAK2 in chronic lymphocytic leukemia2016
Dr Carmela Ciardullo
Dr Peixun Zhou
Dr Elaine Willmore
Professor Christine Harrison FRCPath FMedSci
Dr Andrew Hall
et al.
Impact of the apoptotic regulator DRAK2 in chronic lymphocytic leukemia2016
Alison Page
Dr Ghada Malik
Dr Andrew Hall
Professor Deborah Tweddle
The National Children's Cancer and Leukaemia Group Tissue Bank similar to Facilitating a Comprehensive Range of Paediatric Oncology Research2016
Katie Dormon
Elda Latif
Dr Matthew Bashton
Dr Deepali Pal
Dr Helen Blair
et al.
A Whole Genome In Vivo Crispr Screen in Primary ALL Predicts Leukaemic Relapse2015
Dr Nicola Sunter
Dr Helen Marr
Dr Andrew Hall
Dr Tryfonia Mainou-Fowler
Professor Graham Jackson
et al.
Common variation at 12q24.13 (OAS3) influences chronic lymphocytic leukemia risk2015
Dr Linda Hogarth
Dr Andrew Hall
p21WAF1 modulates drug-induced apoptosis and cell cycle arrest in B-cell precursor acute lymphoblastic leukemia2015
Dr Lindsay Nicholson
Elizabeth Matheson
Lynne Minto
Christopher Keilty
Maryna Sanichar
et al.
Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re-sensitization by JNK inhibition2015
Dr Jeyanthy Eswaran
Dr Paul Sinclair
Professor Olaf Heidenreich
Professor Julie Irving
Dr Lisa Russell
et al.
The pre-B-cell receptor checkpoint in acute lymphoblastic leukaemia2015
Dr Nicola Sunter
Dr Andrew Hall
Dr Tryfonia Mainou-Fowler
Professor Graham Jackson
Professor James Allan
et al.
A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia2014
Dr Vikki Rand
Stephen Johnstone
Dr Rachel Crossland
Sarah Wilkinson
Dr Andrew Hall
et al.
The Genomic Landscape of Relapsed B-Cell Acute Lymphoblastic Leukaemia (B-ALL) in Adolescents and Adults2014
Dr Vikki Rand
Dr Andrew Hall
BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint2013
Dr Klaus Rehe
Kerrie Wilson
Dr Simon Bomken
Dr Daniel Williamson
Professor Julie Irving
et al.
Acute B lymphoblastic leukaemia-propagating cells are present at high frequency in diverse lymphoblast populations2013
Dr Andrew Hall
BACH2 Is Required for Pre-B Cell Receptor Checkpoint Control and p53-Dependent Tumor Surveillance2012
Dr Lindsay Nicholson
Elizabeth Matheson
Lynne Minto
Marian Case
Maryna Sanichar
et al.
Casitas B lymphoma mutations in childhood acute lymphoblastic leukemia2012
Michael Batey
Dr Yan Zhao
Dr Helen Maitland
Professor Hing Leung
Dr Andrew Hall
et al.
Comparative pre-clinical evaluation of receptor tyrosine kinase inhibitors for the treatment of multiple myeloma2011
Dr Sally Coulthard
Dr Chris Redfern
Svante Vikingsson
Dr Malin Lindqvist Appell
Dr Andrew Hall
et al.
Increased Sensitivity to Thiopurines in Methylthioadenosine Phosphorylase-Deleted Cancers2011
Dr Linda Hogarth
Dr Andrew Hall
p53-independent Epigenetic Repression of the p21WAF1 Gene in T-cell Acute Lymphoblastic Leukemia2011
Haya AL-Balool
Dr Mark Wade
Dr Jonathan Coxhead
Professor Julie Irving
Professor David Elliott
et al.
Post-transcriptional exon shuffling events in humans can be evolutionarily conserved and abundant2011
Dr Lindsay Nicholson
Charlotte Evans
Elizabeth Matheson
Lynne Minto
Christopher Keilty
et al.
Quantitative Proteomic Analysis Reveals Maturation As a Mechanism Underlying Glucocorticoid Resistance in Childhood Acute Lymphoblastic Leukemia and PAX5 As a Re-Sensitising Therapeutic Target2011
Professor Graham Jackson
Dr Nicola Sunter
Dr Andrew Hall
Professor Julie Irving
Professor James Allan
et al.
A polymorphism in the 3' UTR of IRF4 linked to susceptibility and pathogenesis in chronic lymphocytic leukaemia and Hodgkin lymphoma has limited impact in multiple myeloma2010
Dr Amy Peasland
Elizabeth Matheson
Dr Andrew Hall
Professor Julie Irving
Alternative splicing of hMLH1 in childhood acute lymphoblastic leukaemia and characterisation of the variably expressed Δ9/10 isoform as a dominant negative species2010
Dr Nicola Sunter
Dr Andrew Hall
Dr Tryfonia Mainou-Fowler
Professor Graham Jackson
Professor James Allan
et al.
Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk2010
Elizabeth Matheson
Lynne Minto
Dr Andrew Hall
Professor Julie Irving
Mismatch repair and the downstream target genes, PAX5 and Ikaros, in childhood acute lymphoblastic leukemia2010
Dr Lindsay Nicholson
Dr Andrew Hall
Dr Chris Redfern
Professor Julie Irving
NF kappa B modulators in a model of glucocorticoid resistant, childhood acute lymphoblastic leukemia2010
Professor James Allan
Dr Nicola Sunter
Dr Andrew Hall
Dr Christopher Bacon
Jonathan Pointon
et al.
Variant IRF4/MUM1 associates with CD38 status and treatment-free survival in chronic lymphocytic leukaemia2010
Sarina Sulong
Professor Anthony Moorman
Professor Julie Irving
Marian Case
Professor Simon Bailey
et al.
A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups2009
Dr Andrew Hall
Frequent CBL mutations associated with 11q acquired uniparental disomy in myeloproliferative neoplasms2009
Dr Tevfik Dorak
Professor Caroline Relton
Professor Louise Parker
Dr Andrew Hall
Hereditary Hemochromatosis Gene (HFE) Variants are Associated with Birth Weight and Childhood Leukemia Risk2009
Dr Lindsay Nicholson
Elizabeth Matheson
Lynne Minto
Christopher Keilty
Dr Andrew Hall
et al.
Quantitative Proteomic Analysis Implicates An Altered B-Cell Differentiation State as a Mechanism Underlying GC-Resistance in An Acute Lymphoblastic Leukaemia (ALL) Cell Line Model2009
Neil Johnson
Professor Nicola Curtin
Dr Andrew Hall

A comparative study of genome-wide SNP, CGH microarray and protein expression analysis to explore genotypic and phenotypic mechanisms of acquired antiestrogen resistance in breast cancer

2008
Professor James Allan
Dr Nicola Sunter
Dr Andrew Hall
Dr Tryfonia Mainou-Fowler
Professor Graham Jackson
et al.
A Common Genetic Variant in the 3'UTR of IRF4/MUM1 Associates with Risk of Disease and Poor Prognosis in Chronic Lymphocytic Leukaemia2008
Dr Nicola Sunter
Dr Andrew Hall
Dr Tryfonia Mainou-Fowler
Professor Graham Jackson
Professor James Allan
et al.
A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia2008
Professor Julie Irving
Lynne Minto
Dr Andrew Hall
Genomic analysis of different clonal evolution in a twin pair with t(12;21) positive acute lymphoblastic leukemia sharing the same prenatal clone [8]2008
Elizabeth Matheson
Lynne Minto
Professor Anthony Moorman
Dr Andrew Hall
Professor Julie Irving
et al.
Heterogeneous breakpoints target PAX5 in acute lymphoblastic leukaemia patients with dicentric chromosomes2008
Michael Batey
Dr Helen Maitland
Professor Hing Leung
Dr Andrew Hall
Professor Graham Jackson
et al.
In vitro activity of the multi targeted receptor tyrosine kinase inhibitor sunitinib against multiple myeloma cell lines is not predictive of in vivo xenograft response2008
Professor Anthony Moorman
Sarina Sulong
Professor Julie Irving
Marian Case
Lynne Minto
et al.
Inactivation of CDKN2A in childhood acute lymphoblastic leukaemia (ALL) occurs principally by deletion and is strongly correlated with cytogenetic subgroups2008
Elizabeth Matheson
Mike Cole
Dr Bridget Wilkins
Dr Andrew Hall
Mismatch repair defects in childhood acute lymphoblastic leukaemia at diagnosis and relapse2008
Marian Case
Elizabeth Matheson
Lynne Minto
Dr Nicholas Bown
Professor Simon Bailey
et al.
Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia2008
Marian Case
Elizabeth Matheson
Lynne Minto
Professor Christine Harrison FRCPath FMedSci
Dr Nicholas Bown
et al.
Somatic mutation of genes impacting on the RAS-RAF-MEK-ERK pathway is the most common genetic abnormality in childhood acute lymphoblastic leukaemia, is implicated in disease progression and provides a rationale for therapeutic targeting2008
Marian Case
Dr Tina Davies
Professor Anthony Moorman
Dr Andrew Hall
Professor Julie Irving
et al.
The complex genomic profile of ETV6-RUNX1 positive acute lymphoblastic leukemia highlights a recurrent deletion of TBL1XR12008
Dr Linda Hogarth
Dr Chris Redfern
Dr Andrew Hall
Dr Holly Anderson
Marian Case
et al.
The effect of thiopurine drugs on DNA methylation in relation to TPMT expression2008
Elizabeth Matheson
Professor Anthony Moorman
Dr Andrew Hall
Professor Christine Harrison FRCPath FMedSci
Professor Julie Irving
et al.
Variable breakpoints target PAX5 in patients with dicentric chromosomes: A model for the basis of unbalanced translocations in cancer2008
Dr Andrew Hall
Acquired isodisomy is common in atypical myeloproliferative disorders2007
Elizabeth Matheson
Dr Linda Hogarth
Marian Case
Professor Julie Irving
Dr Andrew Hall
et al.
DHFR and MSH3 co-amplification in childhood acute lymphoblastic leukaemia, in vitro and in vivo2007
Professor Anthony Moorman
Marian Case
Professor Julie Irving
Dr Andrew Hall
Professor Christine Harrison FRCPath FMedSci
et al.
Genomic profiling reveals multiple genetic targets in ETV6-RUNX1 positive acute lymphoblastic leukaemia (ALL)2007
Dr Jane Carr-Wilkinson
Dr Nicholas Bown
Marian Case
Dr Andrew Hall
Professor John Lunec
et al.
High-resolution analysis of allelic imbalance in neuroblastoma cell lines by single nucleotide polymorphism arrays2007
Dr Maria Lastowska
Dr Mauro Santibanez Koref
Ilka Wappler
Dr Heiko Peters
Dr Andrew Hall
et al.
Identification of candidate genes involved in neuroblastoma progression by combining genomic and expression microarrays with survival data2007
Adillah Binti Yusof
Professor Julie Irving
Marian Case
Lynne Minto
Professor Christine Harrison FRCPath FMedSci
et al.
Red blood cell alloimmunization is affected by depletion of donor white cell subsets2007
Elizabeth Matheson
Lynne Minto
Professor Anthony Moorman
Dr Andrew Hall
Professor Julie Irving
et al.
Variable Breakpoints Target PAX5 in Patients with Dicentric Chromosomes: A Model for the Basis of Unbalanced Translocations in Cancer2007
Dr Andrew Hall
Sarina Sulong
Professor Christine Harrison FRCPath FMedSci
Lynne Minto
Dr Nicholas Bown
et al.
Assessment of aneuploidy in childhood acute lymphoblastic leukaemia using high density oligonucleotide arrays.2006
Dr Akheel Syed
Professor Julie Irving
Dr Chris Redfern
Dr Andrew Hall
Professor Nigel Unwin
et al.
Association of glucocorticoid receptor polymorphism A3669G in exon 9β with reduced central adiposity in women2006
Sarina Sulong
Professor Julie Irving
Marian Case
Lynne Minto
Dr Nicholas Bown
et al.
Comprehensive analysis of p16(INK4a) in childhood acute lymphoblastic leukemia reveals homozygous deletion, haploinsufficiency and acquired isodisomy at the 9p locus with intact p16(INK4a).2006
Marian Case
Dr Andrew Hall
Dr Linda Hogarth
Amanda Jones
Design, synthesis and initial in vitro evaluation of novel prodrugs for the treatment of cystinosis2006
Mark Leslie
Marian Case
Dr Andrew Hall
Dr Sally Coulthard
Expression levels of asparagine synthetase in blasts from children and adults with acute lymphoblastic leukaemia2006
Professor Julie Irving
Lynne Minto
Elizabeth Matheson
Dr Lindsay Nicholson
Dr Andrew Hall
et al.
Glucocorticoid resistance in two key models of acute lymphoblastic leukemia occurs at the level of the glucocorticoid receptor2006
Professor Julie Irving
Lynne Minto
Elizabeth Matheson
Marian Case
Professor Simon Bailey
et al.
Mutation in genes impacting on the RAS-RAF-MEK-ERK pathway are found at high incidence in childhood acute lymphoblastic leukemia at both diagnosis and at relapse.2006
Diana Levett
Professor Roderick Skinner
Dr Andrew Hall
Dr John Hanley
Novel mutations in a child with congenital amegakaryocytic thrombocytopenia2006
Dr Andrew Hall
Professor Julie Irving
Lynne Minto
Reply to 'ATM variants and predisposition to childhood T-lineage acute lymphoblastic leukaemia' by Gumy-Pause et al. [6]2006
Professor Nick Reynolds
Dr Helen Anderson
Gordon Taylor
Dr Andrew Hall
Dr Linda Hogarth
et al.
Thioguanine nucleotide levels correlate with clinical response in atopic eczema patients treated with azathioprine2006
Dr Simon Meggitt
Professor Nick Reynolds
Dr Helen Anderson
Gordon Taylor
Dr Andrew Hall
et al.
Thioguanine nucleotides in patients with moderate-to-severe atopic eczema treated with azathioprine2006
Professor Julie Irving
Dr Andrew Hall
Constitutional segmental uniparental disomy in a twin pair with t(12;21) positive acute lymphoblastic leukemia characterized by the same prenatal clone and divergent clonal evolution2005
Dr Mark Velangi
Elizabeth Matheson
Dr Andrew Hall
Professor Julie Irving
Detecting mismatch repair defects in myeloma2005
Professor Julie Irving
Lynne Minto
Professor Simon Bailey
Dr Andrew Hall
Loss of heterozygosity and somatic mutations of the Glucocorticoid receptor gene are rarely found at relapse in pediatric acute lymphoblastic leukemia but may occur in a subpopulation early in the disease course2005
Professor Julie Irving
Clare Bloodworth
Dr Nicholas Bown
Marian Case
Dr Linda Hogarth
et al.
Loss of heterozygosity in childhood acute lymphoblastic leukemia detected by genome-wide microarray single nucleotide polymorphism analysis2005
Dr Andrew Hall
Professor Julie Irving
Lynne Minto
Relation between genetic variants of the ataxia telangiectasia-mutated (ATM) gene, drug resistance, clinical outcome and predisposition to childhood T-lineage acute lymphoblastic leukaemia2005
Sarina Sulong
Marian Case
Lynne Minto
Dr Bridget Wilkins
Dr Andrew Hall
et al.
The V617F mutation in Jak2 is not found in childhood acute lymphoblastic leukaemia2005
Dr Sandeep Pal
Lynne Minto
Dr Andrew Hall
Antibodies against 9-O-acetylated sialoglycans: A potent marker to monitor clinical status in childhood acute lymphoblastic leukemia2004
Dr Mark Velangi
Elizabeth Matheson
Dr Penelope Taylor
Professor Graham Jackson
Dr Andrew Hall
et al.
BRAF gene is not mutated in mismatch repair-proficient or -deficient plasma cell dyscrasias 2004
Dr Mark Velangi
Elizabeth Matheson
Professor Graham Jackson
Dr Penelope Taylor
Dr Andrew Hall
et al.
DNA mismatch repair pathway defects in the pathogenesis and evolution of myeloma2004
Professor Penny Lovat
Professor Andrew Pearson
Dr Andrew Hall
Dr Chris Redfern
Gangliosides link the acidic sphingomyelinase-mediated induction of ceramide to 12-lipoxygenase-dependent apoptosis of neuroblastoma in response to fenretinide2004
Dr Andrew Hall
Professor Julie Irving
Lynne Minto
Genetic variants of ataxia telangiectasia mutated (ATM) and susceptibility for childhood T-lineage acute lymphoblastic leukemia.2004
Dr Andrew Hall
Clare Bloodworth
Dr Linda Hogarth
Dr Nicholas Bown
Professor Julie Irving
et al.
Loss of heterozygosity in childhood acute lymphoblastic leukaemia detected by genome-wide microarray single nucleotide polymorphism analysis2004
Dr Akheel Syed
Professor Julie Irving
Dr Chris Redfern
Dr Andrew Hall
Professor Nigel Unwin
et al.
Low Prevalence of the N363S Polymorphism of the Glucocorticoid Receptor in South Asians Living in the United Kingdom2004
Dr Sally Coulthard
Dr Andrew Hall
Dr Linda Hogarth
The clinical impact of thiopurine methyltransferase polymorphisms on thiopurine treatment2004
Professor Julie Irving
Professor Stephen O'Brien
Dr Anne Lennard
Lynne Minto
Dr Feng Lin
et al.
Use of Denaturing HPLC for Detection of Mutations in the BCR-ABL Kinase Domain in Patients Resistant to Imatinib2004
Elizabeth Matheson
Dr Andrew Hall
Assessment of mismatch repair function in leukaemic cell lines and blasts from children with acute lymphoblastic leukaemia2003
Dr Andrew Hall
ATM (Ataxia Telangiectasia Mutated) gene alterations are frequently found in childhood T-ALL2003
Dr Mark Velangi
Professor Graham Jackson
Dr Penelope Taylor
Dr Andrew Hall
Professor Julie Irving
et al.
DNA mismatch repair pathway defects in the pathogenesis and evolution of myeloma2003
Dr Pamela Kearns
Professor Zofia Chrzanowska-Lightowlers
Dr Andrew Hall
Expression of GSTM isoforms in childhood acute lymphoblastoid leukaemia2003
Elizabeth Matheson
Dr Andrew Hall
Interactions of the DNA mismatch repair proteins MLH1 and MSH2 with c-MYC and MAX2003
Penelope Mason
Elizabeth Matheson
Dr Andrew Hall
Professor Robert Lightowlers
Mismatch repair activity in mammalian mitochondria2003
Dr Andrew Hall
Elizabeth Matheson
Mismatch repair defects in acute lymphoblastic leukaemia2003
Dr Andrew Hall
Dr Sally Coulthard
Professor Julie Irving
Molecular diagnostics: a healthcare perspective2003
Dr Pamela Kearns
Professor Zofia Chrzanowska-Lightowlers
Dr Andrew Hall
Mu class glutathione S-transferase mRNA isoform expression in acute lymphoblastic leukaemia2003
Mark Leslie
Marian Case
Dr Andrew Hall
Dr Sally Coulthard
Potential use of asparagine synthetase levels in the individualisation of L-asparaginase therapy2003
Clare Bloodworth
Dr Linda Hogarth
Dr Andrew Hall
Role of mismatch repair in determining sensitivity to the topoisomerase II poisons2003
Dr Linda Hogarth
Dr Sally Coulthard
Dr Andrew Hall
Lindi Skitt
The effect of thiopurine methyltransferase on the cytotoxic action of thiopurine drugs2003
Professor Julie Irving
Professor Stephen O'Brien
Dr Anne Lennard
Dr Feng Lin
Dr Andrew Hall
et al.
The use of denaturing high-performance liquid chromatography (DHPLC) for the detection of mutations in the bcr-abl oncogene in patients resistant to imatinib2003
Nadia Thornton
Dr Andrew Hall
Dr Sally Coulthard
The use of real-time PCR to validate methylthioadenosine phosphorylase and p16 deletions as a new drug target in childhood acute lymphoblastic leukaemia2003
Dr Andrew Hall
Cellular glutathione content, in vitro chemoresponse, and the effect of BSO modulation in samples derived from patients with advanced ovarian cancer2002
Diana Levett
Dr Andrew Hall
Dr John Hanley
Professor Julie Irving
Comparitive study of conformation sensitive gel electrophoresis (CSGE) and denaturing high pressure liquid chromatography (DHPLC) for mutation detection in von Willebrands disease2002
Dr John Anderson
Dr Katrina Wood
Professor John Lunec
Dr Andrew Hall
Dr Michael Reid
et al.
Loss of nuclear expression of the p33ING1b inhibitor of growth protein in childhood acute lymphoblastic leukaemia2002
Dr Andrew Hall
Professor Julie Irving
New drugs, new drug resistance mechanisms2002
Dr Sally Coulthard
Dr Linda Hogarth
Dr Margaret Little
Elizabeth Matheson
Dr Chris Redfern
et al.
The effect of thiopurine methyltransferase expression on sensitivity to thiopurine drugs2002
Elizabeth Matheson
Dr Andrew Hall
Drug discovery - High throughput automated 2-D gel analysis - Tutorial: Proteomic analysis with nonlinear dynamics' progenesis image analysis software2001
Dr Linda Hogarth
Dr Margaret Little
Lynne Minto
Dr Chris Redfern
Dr Andrew Hall
et al.
High thiopurine methyltransferase expression confers different levels of resistance with 6-thioguanine compared to 6-mercaptopurine.2001
Dr Linda Hogarth
Dr Margaret Little
Lynne Minto
Dr Chris Redfern
Dr Andrew Hall
et al.
In vitro evidence for differences in 6-mercaptopurine versus 6-thioguanine metabolism depending on TPMT status2001
Mark Leslie
Marian Case
Dr Andrew Hall
Dr Sally Coulthard
Measurement of aspargine synthetase mRNA levels by real-time PCR2001
Professor Julie Irving
Dr Andrew Hall
Mismatch repair defects as a cause of resistance to cytotoxic drugs2001
Dr John Anderson
Professor John Lunec
Dr Andrew Hall
Dr Michael Reid
Dr Brian Angus
et al.
p33(ING1b) tumour suppresser protein expression in childhood acute lymphoblastic leukaemia by immunohistochemistry2001
Professor Ann Daly
Dr Andrew Hall
Pharmacogenetics of cytotoxic drugs2001
Dr Pamela Kearns
Professor Andrew Pearson
Dr Andrew Hall
Raised blast glutathione levels are associated with an increased risk of relapse in childhood acute lymphocytic leukemia2001
Dr Sally Coulthard
Dr Andrew Hall
Recent advances in the pharmacogenomics of thiopurine methyltransferase2001
Professor Julie Irving
Dr Penelope Taylor
Professor Graham Jackson
Dr Andrew Hall
The presence of mismatch repair defects in plasma cell dyscrasias2001
Professor Simon Bailey
Dr Andrew Hall
Professor Andrew Pearson
Dr Chris Redfern
The role of AP-1 in glucocorticoid resistance in leukaemia2001
Dr Andrew Hall
Dr Peter Hamilton
Lynne Minto
Dr Sally Coulthard
The use of denaturing high-pressure liquid chromatography for the detection of mutations in thiopurine methyltransferase2001
Dr Sally Coulthard
Dr Christopher Howell
Lynne Minto
Dr Peter Middleton
Professor Graham Jackson
et al.
A comparison of molecular and enzyme-based assays for the detection of thiopurine methyltransferase mutations2000
Dr Andrew Hall
Demonstration of functional DNA mismatch repair in lymphoblasts from patients with leukaemia2000
Marian Case
Dr Andrew Hall
Glutathione homeostasis in buthionine sulfoximine sensitive and resistant neuroblastoma cell lines2000
Dr Sally Coulthard
Dr Linda Hogarth
Lynne Minto
Dr Chris Redfern
Dr Andrew Hall
et al.
High thiopurine methyltransferase expression confers different levels of resistance with 6-thioguanine compared to 6-mercaptopurine2000
Dr Linda Hogarth
Elizabeth Matheson
Lynne Minto
Dr Margaret Little
Dr Andrew Hall
et al.
Measurement of resistance to thiopurine drugs in cells with defective mismatch repair2000
Dr Andrew Hall
Optimizing antimetabolite-based chemotherapy for the treatment of childhood acute lymphoblastic leukaemia2000
Dr Andrew Hall
Analysis of thiopurine methyltransferase variant alleles in childhood acute lymphoblastic leukaemia1999
Dr Pamela Kearns
Dr Andrew Hall
Professor Andrew Pearson
Different expression of glutathione S-transferase α, µ and π in childhood acute lymphoblastic and myeloid leukaemia1999
Dr Andrew Hall
Evidence for the involvement of the glutathione pathway in drug resistance in AML1999
Professor Simon Bailey
Dr Andrew Hall
Professor Andrew Pearson
Dr Michael Reid
Dr Chris Redfern
et al.
Glucocorticoid resistance and the AP-1 transcription factor in leukaemia1999
Dr Andrew Hall
Glutathione and the regulation of cell death1999
Dr Pamela Kearns
Professor Andrew Pearson
Dr Andrew Hall
Glutathione in childhood acute leukaemias1999
Dr Linda Hogarth
Dr Andrew Hall
Increased BAX expression is associated with an increased risk of relapse in childhood acute lymphocytic leukemia1999
Andrew Lodge
Dr Andrew Hall
Dr Katrina Wood
Dr John Anderson
Dr Brian Angus
et al.
NCL-CD10-270: A new monoclonal antibody recognizing CD10 in paraffin- embedded tissue1999
Dr Andrew Hall
The role of glutathione in the regulation of apoptosis1999
Andrew Lodge
Dr Andrew Hall
Dr John Anderson
Dr Michael Reid
Dr Brian Angus
et al.

A study of the prognostic significance of topoisomerase IIα in childhood acute lymphoblastic Leukaemia

1998
Professor Roderick Skinner
Dr Andrew Hall
Professor Andrew Pearson
Acute changes in urine protein excretion may predict chronic ifosfamide nephrotoxicity: a preliminary observation1998
Dr Pamela Kearns
Dr Andrew Hall
Glutathione and the response of malignant cells to chemotherapy1998
Dr Pamela Kearns
Professor Andrew Pearson
Dr Andrew Hall
Glutathione levels in leukaemic blasts1998
Dr Sally Coulthard
Dr Christopher Howell
Jill Robson
Dr Andrew Hall
The relationship between thiopurine methyltransferase activity and genotype in blasts from patients with acute leukemia1998
Dr Andrew Hall
Professor John Lunec
Professor Herbie Newell
Professor Andrew Pearson
Geoffrey Taylor
et al.
Thymidylate synthase expression in nolatrexed and methotrexate-resistant human leukaemia cell lines1998
Dr Pamela Kearns
Dr Andrew Hall
Alkylating agent resistance in pediatric oncology1997
Professor Alan Calvert
Dr Andrew Hall
Professor John Lunec
Professor Herbie Newell
Professor Andrew Pearson
et al.
The relationship between intrinsic thymidylate synthase expression and sensitivity to THYMITAQ® in human leukaemia and colorectal carcinoma cell lines1997
Dr Andrew Hall
Dr Janet McLelland
Thiopurine methyltransferase levels should be measured before commencing patients on azathioprine1997
Dr Andrew Hall
Professor Graham Jackson
Congenital deficiency of thiopurine methyltransferase as a cause of pancytopenia in patients treated with azathioprine1996
Dr Andrew Hall
Dr Linda Hogarth
Sensitivity of testis tumour cells to chemotherapeutic drugs: Role of detoxifying pathways1996
Dr Linda Hogarth
Professor Andrew Pearson
Dr Andrew Hall
The effect of treatment with high dose melphalan, cisplatin or carboplatin on levels of glutathione in plasma, erythrocytes, mononuclear cells and urine1996
Dr Andrew Hall
Professor Alan Calvert
Dr James Sunter
Professor Herbie Newell
The relationship between tumour glutathione concentration, glutathione S-transferase isoenzyme expression and response to single agent carboplatin in epithelial ovarian cancer patients1996
Dr Michael Reid
Elizabeth Matheson
Dr Penelope Taylor
Professor Stephen Proctor
Dr Andrew Hall
et al.

Corticosteroid resistance is increased in lymphoblasts from adults compared with children: preliminary results of in vitro drug sensitivity study in adults with acute lymphoblastic leukaemia

1995
Dr Andrew Hall
Second primary head and neck squamous cell carcinoma predicted by the glutathione S-transferase expression in healthy tissue in the direct vicinity of the first tumor1995
Dr Andrew Hall
Professor Archibald Malcolm
Mike Cole
Dr Jennifer Kernahan
Dr Michael Reid
et al.
Expression of mu class glutathione S-transferase correlates with event-free survival in childhood acute lymphoblastic leukemia1994
Dr Andrew Hall
Professor Andrew Pearson
Professor Archibald Malcolm
Dr Michael Reid
Glutathione S-transferase in bone marrow metastases of disseminated neuroblastoma1994
Dr Andrew Hall
Professor Hermann Josef Vormoor
Increased DNA-repair capacity and the modulation of 2 proteins in and metallothionein overexpressing Chinese hamster cell line1994
Dr Andrew Hall
Elizabeth Matheson
Dr Linda Hogarth
Purification of an alpha class glutathione S-transferase from melphalan-resistant Chinese hamster ovary cells and demonstration of its ability to catalyze melphalan-glutathione adduct formation1994
Dr Linda Hogarth
Dr Michael Reid
Professor Stephen Proctor
Dr Peter Hamilton
Dr Andrew Hall
et al.
Raised intracellular glutathione levels correlate with in vitro resistance to cytotoxic drugs in leukaemic cells from patients with acute lymphoblastic leukaemia1994
Dr Michael Reid
Professor Andrew Pearson
Professor Stephen Proctor
Dr Peter Hamilton
Dr Andrew Hall
et al.
The relationship between bcl-2 expression and response to chemotherapy in acute leukaemia1994
Dr Linda Hogarth
Dr Andrew Hall
Cytosolic glutathione (GSH) levels of leukemic blasts in relation to in vitro anthracycline resistance1993
Dr Andrew Hall
Professor Robert Lightowlers
Identification of bovine glutamate dehydrogenase as an RNA-binding protein1993
Dr Andrew Hall
Dr Michael Reid
Professor Stephen Proctor
Invitro drug sensitivity testing in acute lymphoblastic-leukemia using the tetrazolium-based MTT assay1993
Dr Andrew Hall
Deanne Crowther
Glutathione S-transferase activity and isoenzyme distribution in ovarian tumour biopsies taken before or after cytotoxic chemotherapy1992
Dr Andrew Hall
Dr Robert Nelson
Professor Alastair Burt
Glutathione S-transferases in neonatal liver disease1992
Craig Wright
Dr Andrew Hall
Immunohistochemical demonstration of glutathione S-transferases in primary human breast carcinomas1992
Dr Andrew Hall
Dr Michael Tilby
Mechanisms of action of, and modes of resistance to, alkylating agents used in the treatment of haematological malignancies 1992
Professor Craig Robson
Dr Andrew Hall
Reduced topoisomerase II and elevated α class glutathione S-transferase expression in a multidrug resistant CHO cell line highly cross-resistant to mitomycin C1992
Dr Christopher Wright
Dr Andrew Hall
Response to mitoxantrone in advanced breast cancer: correlation with expression of c-erbB-2 protein and glutathione S-transferases1992
Dr Sally Davies
Dr Andrew Hall
Isolation and partial characterisation of a mammalian cell mutant hypersensitive to topoisomerase II inhibitors and X-rays
1990
Dr Brian Angus
Dr Andrew Hall
Professor Stephen Proctor
Glutathione S-transferase (placental) as a marker of transformation in the human cervix uteri: an immunohistochemical study1990
Dr Andrew Hall
Professor Stephen Proctor
Purification and characterization of a pi class glutathione S-transferase from human leukaemic cells1990
Dr Andrew Hall
Dr Charles Kelly
Exercise testing soon after myocardial infarction: its relation to course and outcome at one year in patients aged less than 55 years1989
Dr Andrew Hall
Professor Stephen Proctor
Mechanisms of drug resistance in acute leukaemia1989
Dr Andrew Hall
Professor Craig Robson
Professor Stephen Proctor
Possible role of inhibition of glutathione S-transferase in the partial reversal of chlorambucil resistance by indomethacin in a Chinese hamster ovary cell line1989
Dr Andrew Hall
Professor Craig Robson
Professor Stephen Proctor

Potentation of alkylating agents using indomethacin

1988
Professor Craig Robson
Dr Andrew Hall
Bleomycin and X-ray-hypersensitive Chinese hamster ovary cell mutants: Genetic analysis and cross-resistance to neocarzinostatin1988
Dr Andrew Hall
Professor Stephen Proctor
Case report: Hodgkin's disease involving the large bowel1988
Dr Andrew Hall
Professor Stephen Proctor
Dr Peter Saunders

Increased platelet associated immunoglobulin in myelodysplastic syndromes

1987
Dr Andrew Hall
Professor Anne Dickinson
Professor Stephen Proctor
Measurement of in vitro drug sensitivity to human myeloma and chronic lymphocytic-leukemia1987
Professor Craig Robson
Dr Andrew Hall
Professor Stephen Proctor
Reduced levels of drug-induced DNA cross-linking in nitrogen mustard-resistant Chinese hamster ovary cells expressing elevated glutathione S-transferase activity1987
Dr Andrew Hall
Professor Stephen Proctor
Melphalan resistance in myeloma1986
Professor Stephen Proctor
Dr Peter Hamilton
Dr Michael Reid
Dr Andrew Hall
Progress in acute leukaemia in adults1986