Publications by Dr Marie-Helene Ruchaud - ePrints

Browsing publications by Dr Marie-Helene Ruchaud.

Newcastle Authors	Title	Year
Dr Kathryn Musgrave Dr Jonathan Scott Dr Wezi Sendama Aaron Gardner Fiona Dewar et al.	Tissue factor expression in monocyte subsets during human immunothrombosis, endotoxemia and sepsis	2023
Dr Wendy Funston Dr Marie-Helene Ruchaud Jonathan Scott Jason Powell Dr Faye Cooles et al.	A human model of bilateral pulmonary vein sampling to assess the effects of one-lung ventilation on neutrophil function	2022
Dr Jack Leslie Dr Marie-Helene Ruchaud Amy Collins Leena Habiballa Dr Gabi Saretzki et al.	Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner	2021
Jonathan Scott Dr Marie-Helene Ruchaud Dr Kate Musgrave Dr Stephen Wright Dr John Perry et al.	Phosphoinositide 3-kinase δ inhibition improves neutrophil bacterial killing in critically ill patients at high risk of infection	2021
Dr Marie-Helene Ruchaud Jonathan Scott Professor John Simpson	C5a impairs phagosomal maturation in the neutrophil through phosphoproteomic remodeling	2020
Dr Jim Macfarlane Dr Marie-Helene Ruchaud Jonathan Scott Professor John Simpson	Src kinase inhibition with dasatinib impairs neutrophil function and clearance of Escherichia coli infection in a murine model of acute lung injury	2020
Dr Kathryn Musgrave Jonathan Scott Dr Wezi Sendama Dr Patrick Kesteven Dr Marie-Helene Ruchaud et al.	The differential surface expression of tissue factor between monocyte subsets	2020
Dr Laura Jardine Dr Sarah Wiscombe Dr Gary Reynolds Dr David McDonald Andrew Fuller et al.	Lipopolysaccharide inhalation recruits monocytes and dendritic cell subsets to the alveolar airspace.	2019
Jason Powell Dr James Garnett Dr Michael Mather Dr Faye Cooles Dr Bernard Verdon et al.	Excess Mucin Impairs Subglottic Epithelial Host Defense in Mechanically Ventilated Patients	2018
Dr John Widdrington Dr Aurora Gomez Duran Dr Angela Pyle Dr Marie-Helene Ruchaud Jonathan Scott et al.	Exposure of Monocytic Cells to Lipopolysaccharide Induces Coordinated Endotoxin Tolerance, Mitochondrial Biogenesis, Mitophagy, and Antioxidant Defenses	2018
Dr Emma Pinder Dr Anthony Rostron Dr Tom Hellyer Dr Marie-Helene Ruchaud Jonathan Scott et al.	Randomised controlled trial of GM-CSF in critically ill patients with impaired neutrophil phagocytosis	2018
Dr John Widdrington Dr Aurora Gomez Duran Dr Jannetta Steyn Dr Angela Pyle Dr Marie-Helene Ruchaud et al.	Mitochondrial DNA depletion induces innate immune dysfunction rescued by IFN-γ	2017
Jonathan Scott Dr Jim Macfarlane Dr Tom Hellyer Dr Anthony Rostron Dr Marie-Helene Ruchaud et al.	Exchange protein directly activated by cyclic AMP (EPAC) activation reverses neutrophil dysfunction induced by beta(2)-agonists, corticosteroids, and critical illness	2016
Dr Marie-Helene Ruchaud Dr Jenny Grant Dr Logan Thirugnanasothy Sasiharan Sithamparanathan Emeritus Professor Nick Europe-Finner et al.	Investigation Of Neutrophil Function In Ipah Patients	2016
Dr Emma Pinder Dr Anthony Rostron Thomas Hellyer Dr Marie-Helene Ruchaud Jonathan Scott et al.	Randomised Controlled Trial Of Granulocyte Macrophage Colony Stimulating Factor In Critically Ill Patients With Impaired Neutrophil Function	2016
Dr Tom Hellyer Dr Simon Baudouin Dr Stephen Wright Melinda Jeffels Dr Marie-Helene Ruchaud et al.	Diagnostic accuracy of pulmonary host inflammatory mediators in the exclusion of ventilator-acquired pneumonia	2015
Dr Jim Macfarlane Jonathan Scott Dr Marie-Helene Ruchaud Dr Anjam Khan Professor John Simpson et al.	Src/bcr-abl Inhibition with Dasatinib in Sterile and Non-Sterile Acute Lung Inflammation	2014
Dr Marie-Helene Ruchaud Jonathan Scott Professor John Simpson	MPLA inhibits release of cytotoxic mediators from human neutrophils while preserving efficient bacterial killing	2014
Dr Catherine Popplewell Dr Marie-Helene Ruchaud Jonathan Scott Emeritus Professor Nick Europe-Finner Professor John Simpson et al.	Carboplatin and Gemcitabine Impair Neutrophil Phagocytic Function	2013
Dr Marie-Helene Ruchaud Dr Katy Hester Dr Jim Macfarlane Emeritus Professor Nick Europe-Finner Professor John Simpson et al.	Effect of granulocyte-macrophage colony-stimulating factor on neutrophil function in idiopathic bronchiectasis	2013
Dr Jim Macfarlane Dr Marie-Helene Ruchaud Jonathan Scott Dr David Bulmer Dr Anjam Khan et al.	Src Kinase Inhibition Attenuates Neutrophil Degranulation Without Impairing Bacterial Killing: A Possible Therapeutic Strategy for Acute Lung Injury?	2013
Dr Marie-Helene Ruchaud Professor Brendan Kenny	Proteasome-independent degradation of canonical NFκB complex components by the NleC protein of pathogenic Escherichia coli	2011
Dr Marie-Helene Ruchaud Dr Paul Dean Professor Brendan Kenny	The Enteropathogenic E. coli (EPEC) Tir Effector Inhibits NF-κB Activity by Targeting TNFα Receptor-Associated Factors	2011
Dr Marie-Helene Ruchaud Professor Brendan Kenny	Enteropathogenic Escherichia coli (EPEC) inactivate innate immune responses prior to compromising epithelial barrier function	2007
Dr Marie-Helene Ruchaud	A critical threshold of β2-integrin engagement regulates augmentation of cytokine-mediated superoxide anion release	2004
Dr Meiyi Pu Dr Felicity May Dr Marie-Helene Ruchaud Professor Bruce Westley	Development of a two-site ELISA assay for the dimeric form of human TFF1	2004
Dr Marie-Helene Ruchaud Professor Bruce Westley Dr Felicity May	The trefoil protein TFF1 is bound to MUC5AC in human gastric mucosa	2004
Dr Marie-Helene Ruchaud	Soluble E-selectin acts in synergy with platelet-activating factor to activate neutrophil beta 2-integrins. Role of tyrosine kinases and Ca²⁺ mobilization	2000
Dr Marie-Helene Ruchaud	Differential effects of bacterial lipopolysaccharides upon neutrophil function	1998
Dr Marie-Helene Ruchaud	Mapping the epitope of a functional P-selectin monoclonal antibody (LYP20) to a short complement-like repeat (SCR 4) domain: use of human-mouse chimaera and homologue-replacement mutagenesis	1998
Dr Marie-Helene Ruchaud	Potential pro-inflammatory effects of soluble E-selectin upon neutrophil function	1998
Dr Marie-Helene Ruchaud	Activation of neutrophil function via CD66: differential effects upon beta 2 integrin mediated adhesion	1997
Dr Marie-Helene Ruchaud	CD66: role in the regulation of neutrophil effector function	1996