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Browsing publications by Dr Tuomo Polvikoski.

Newcastle AuthorsTitleYearFull text
Dr Tuomo Polvikoski
Professor Tiago Outeiro
Dr Ahmad Khundakar
Glycosylation spectral signatures for glioma grade discrimination using Raman spectroscopy2023
Dr Yi Ng
Dr Nichola Lax
Dr Alasdair Blain
Dr Daniel Erskine
Professor Mark Baker
et al.
Forecasting stroke-like episodes and outcomes in mitochondrial disease2022
Professor Carol Brayne
Professor Johannes Attems
Professor Fiona Matthews
Dr Tuomo Polvikoski
Frequency of LATE neuropathologic change across the spectrum of Alzheimer's disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts2022
Dr Sabine Specht
Dr Jennifer Duff
Dr Richard Charlton
Dr Tuomo Polvikoski
Dr Rita Barresi
et al.
A cryptic intronic LAMA2 insertion in a boy with mild congenital muscular dystrophy type 1A2021
Professor Raj Kalaria
Dr Tuomo Polvikoski
Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores2021
Jack Collier
Dr Monika Olahova
Dr Nuria Martinez Lopez
Dr Tuomo Polvikoski
Dr Andrew Schaefer
et al.
Developmental consequences of defective Atg7-mediated autophagy in humans2021
Dr Ren Ding
Dr Yoshiki Hase
Matthew Burke
Vincent Foster
William Stevenson
et al.
Loss with ageing but preservation of frontal cortical capillary pericytes in post-stroke dementia, vascular dementia and Alzheimer’s disease2021
Professor Johannes Attems
Dr Lauren Walker
Dr Kirsty McAleese
Dr Tuomo Polvikoski
Professor Ian McKeith
et al.
Neuropathological consensus criteria for the evaluation of Lewy pathology in post-mortem brains: a multi-centre study2021
Dr Timothy Williams
Professor Mark Baker
Dr Tuomo Polvikoski
TDP-43 proteinopathies: A new wave of neurodegenerative diseases2021
Dr Daniel Erskine
Dr Amy Reeve
Dr Tuomo Polvikoski
Dr Andrew Schaefer
Professor Robert Taylor
et al.
Lewy body pathology is more prevalent in older individuals with mitochondrial disease than controls2020
Dr Ren Ding
Dr Yoshiki Hase
Kamar Ameen-Ali
Michael Ndung'U
William Stevenson
et al.
Loss of capillary pericytes and the blood–brain barrier in white matter in poststroke and vascular dementias and Alzheimer’s disease2020
Professor Fiona Matthews
Dr Tuomo Polvikoski
Professor Carol Brayne
Putative risk alleles for LATE‐NC with hippocampal sclerosis in population‐representative autopsy cohorts2020
Dr Yoshiki Hase
Dr Tuomo Polvikoski
Dr Michael Firbank
Dr Lucinda Craggs
William Stevenson
et al.
Small vessel disease pathological changes in neurodegenerative and vascular dementias concomitant with autonomic dysfunction2020
Dr Yoshiki Hase
Dr Tuomo Polvikoski
Dr Mai Hase
William Stevenson
Dr Louise Allan
et al.
Carotid artery disease in post-stroke survivors and effects of enriched environment on stroke pathology in a mouse model of carotid artery stenosis2019
Dr Veronika Boczonadi
Dr Monika Olahova
Dr Boglárka Bánsági
Dr Andreas Roos
Dr Vankateswara Ramesh
et al.
Correction: Mitochondrial oxodicarboxylate carrier deficiency is associated with mitochondrial DNA depletion and spinal muscular atrophy–like disease (Genetics in Medicine, (2018), 20, 10, (1224-1235), 10.1038/gim.2017.251)2019
Dr Tuomo Polvikoski
Lewy-related pathology exhibits two anatomically and genetically distinct progression patterns: a population-based study of Finns aged 85+2019
Dr Tuomo Polvikoski
Prediction models for dementia and neuropathology in the oldest old: the Vantaa 85+ cohort study2019
Dr Lizzie Harris
Dr Chiara Marini Bettolo
Dr Ana Topf
Dr Rita Barresi
Dr Tuomo Polvikoski
et al.
MEGF10 related myopathies: A new case with adult onset disease with prominent respiratory failure and review of reported phenotypes2018
Dr Tuomo Polvikoski
Dr Thais Minett
Professor Fiona Matthews
Professor Carol Brayne
Hippocampal sclerosis, hippocampal neuron loss patterns and TDP-43 in the aged population2018
Dr Veronika Boczonadi
Dr Monika Olahova
Dr Boglarka Bansagi
Dr Andreas Roos
Dr Vankateswara Ramesh
et al.
Mitochondrial oxodicarboxylate carrier deficiency is associated with mitochondrial DNA depletion and spinal muscular atrophy–like disease2018
Dr Lizzie Harris
Dr Umar Burki
Dr Chiara Marini Bettolo
Dr Marta Bertoli
Dr Teresinha Evangelista
et al.
Complex phenotypes associated with STIM1 mutations in both coiled coil and EF-hand domains2017
Dr Aiqing Chen
Dr Rufus Akinyemi
Dr Yoshiki Hase
Dr Michael Firbank
Michael Ndung'U
et al.
Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia2016
Dr Tracey Willis
Dr Claire Wood
Dr Tuomo Polvikoski
Dr Rita Barresi
Professor Hanns Lochmuller
et al.
Muscle hypertrophy as the presenting sign in a patient with a complete FHL1 deletion2016
Sebastian Figueroa Bonaparte
Dr Rita Barresi
Dr Tuomo Polvikoski
Dr Timothy Williams
Dr Ana Topf
et al.
Mutational spectrum and phenotypic variability of VCP-related neurological disease in the UK2016
Dr David Lewis-Smith
Dr Jennifer Duff
Dr Angela Pyle
Dr Helen Griffin
Dr Tuomo Polvikoski
et al.
Novel HSPB1 mutation causes both motor neuronopathy and distal myopathy2016
Professor Fiona Matthews
Dr Tuomo Polvikoski
Old-age hippocampal sclerosis associates with GRN and TMEM106B but not with ABCC9 variation in population-based cohorts2016
Dr Tuomo Polvikoski
Professor Fiona Matthews
Old-age hippocampal sclerosis and Alzheimer's disease present with similar clinical characteristics: A population-based study2015
Dr Tuomo Polvikoski
Professor Fiona Matthews
Old-age hippocampal sclerosis associates with grn but not with ABCC9 gene variation in the population2015
Dr Teresinha Evangelista
Dr Boglarka Bansagi
Dr Angela Pyle
Dr Helen Griffin
Dr Konstantinos Douroudis
et al.
Phenotypic variability of TRPV4 related neuropathies2015
Dr Tuomo Polvikoski
Dr Elizabeta Mukaetova-Ladinska
Re-examining tau-immunoreactive pathology in the population: granulovacuolar degeneration and neurofibrillary tangles2015
Dr Veronika Boczonadi
Dr Juliane Mueller
Dr Angela Pyle
Dr Jennifer Munkley
Michele Giunta
et al.
EXOSC8 mutations alter mRNA metabolism and cause hypomyelination with spinal muscular atrophy and cerebellar hypoplasia2014
Vincent Foster
Arthur Oakley
Janet Slade
Roslyn Hall
Dr Tuomo Polvikoski
et al.
Pyramidal neurons of the prefrontal cortex in post-stroke, vascular and other ageing-related dementias2014
Dr Benjamin Davison
Dr Tuomo Polvikoski
Dr Jannath Ahmed
The impact of thrombus aspiration on luminal expansion: the intra-vascular ultrasound study of thrombectomy in ST elevation myocardial infarction patients2014
Dr Amina Chaouch
Dr Fiona Norwood
Professor Rita Horvath
Professor Patrick Chinnery
Dr Tuomo Polvikoski
et al.
Two recurrent mutations are associated with GNE myopathy in the North of Britain2014
Dr Tuomo Polvikoski
Amyloid precursor protein (APP) A673T mutation in the elderly Finnish population2013
Dr Nichola Lax
Dr Charlotte Alston
Dr Tuomo Polvikoski
Dr Evelyn Jaros
Dr John Yarham
et al.
Early-Onset Cataracts, Spastic Paraparesis, and Ataxia Caused by a Novel Mitochondrial tRNA(Glu) (MT-TE) Gene Mutation Causing Severe Complex I Deficiency: A Clinical, Molecular, and Neuropathologic Study2013
Dr Kelvin Lee
Dr Mauro Santibanez Koref
Dr Tuomo Polvikoski
Dr Daniel Birchall
Emeritus Professor David Mendelow
et al.
Increased expression of fatty acid binding protein 4 and leptin in resident macrophages characterises atherosclerotic plaque rupture2013
Dr Louise Allan
Dr Elise Rowan
Professor Alan Thomas
Dr Tuomo Polvikoski
Professor John O'Brien
et al.
Long-term incidence of depression and predictors of depressive symptoms in older stroke survivors2013
Graham Campbell
Dr Amy Reeve
Dr Iryna Ziabreva
Dr Tuomo Polvikoski
Professor Robert Taylor
et al.
Mitochondrial DNA deletions and depletion within paraspinal muscles2013
Dr Tuomo Polvikoski
Dr Timo Erkinjuntti
Plasma homocysteine, Alzheimer and cerebrovascular pathology: a population-based autopsy study2013
Matias Wagner
Dr Amina Chaouch
Dr Juliane Mueller
Dr Tuomo Polvikoski
Dr Tracey Willis
et al.
Presymptomatic late-onset Pompe disease identified by the dried blood spot test2013
Dr Tuomo Polvikoski
Delirium is a strong risk factor for dementia in the oldest-old: a population-based cohort study2012
Dr Timothy Bates
Dr Tuomo Polvikoski
Professor Philip Sloan
Dr David Meikle
Dr Max Robinson
et al.
Ganglioneuroblastic transformation in olfactory neuroblastoma2012
Lizzie Gemmell
Dr Helen Bosomworth
Dr Louise Allan
Roslyn Hall
Dr Ahmad Khundakar
et al.
Hippocampal Neuronal Atrophy and Cognitive Function in Delayed Poststroke and Aging-Related Dementias2012
Dr Helen Bosomworth
Dr Ahmad Khundakar
Dr Tuomo Polvikoski
Professor Raj Kalaria
Hippocampal neuronal densities and volumes in ageing related dementias and post-stroke survivors2012
Dr Tuomo Polvikoski
Prevalence and severity of cerebral amyloid angiopathy: a population-based study on very elderly Finns (Vantaa 85+)2012
Dr Anna Sarkozy
Dr Tuomo Polvikoski
Dr Michelle Eagle
Professor Hanns Lochmuller
Emerita Professor Katherine Bushby
et al.
Progressive core myopathy with dilated cardiomyopathy, respiratory failure and severe scoliosis caused by a novel mutation in the MYH7 gene2012
Dr Debbie Hicks
Dr Anna Sarkozy
Dr Nuria Muelas Gomez
Professor Gavin Hudson
Professor Patrick Chinnery
et al.
A founder mutation in Anoctamin 5 is a major cause of limb girdle muscular dystrophy2011
Dr Debbie Hicks
Dr Anna Sarkozy
Dr Nuria Muelas Gomez
Professor Gavin Hudson
Professor Patrick Chinnery
et al.
A founder mutation in Anoctamin 5 is a major cause of limb-girdle muscular dystrophy2011
Dr Tuomo Polvikoski
APOE and AβPP Gene Variation in Cortical and Cerebrovascular Amyloid-β Pathology and Alzheimer’s Disease: A Population-Based Analysis2011
Dr Louise Allan
Dr Elise Rowan
Dr Michael Firbank
Professor Alan Thomas
Dr Steve Parry
et al.
Long term incidence of dementia, predictors of mortality and pathological diagnosis in older stroke survivors2011
Dr Brian Wilson
Dr Tuomo Polvikoski
Astrocytoma in a Breast Cancer Lineage: Part of the BRCA2 Phenotype?2010
Dr Tuomo Polvikoski
Brain neurons express ornithine decarboxylase-activating antizyme inhibitor 2 with accumulation in Alzheimer's disease2010
Dr Tuomo Polvikoski
Diabetes, Alzheimer disease, and vascular dementia: A population-based neuropathologic study2010
Professor Carol Brayne
Professor Ian McKeith
Professor Fiona Matthews
Dr Tuomo Polvikoski
Education, the brain and dementia: neuroprotection or compensation? EClipSE Collaborative Members2010
Dr Tuomo Polvikoski
Dr Timo Erkinjuntti
Professor Raj Kalaria
Frontal lobe white matter hyperintensities and neurofibrillary pathology in the oldest old2010
Dr Masafumi Ihara
Dr Tuomo Polvikoski
Roslyn Hall
Janet Slade
Arthur Oakley
et al.
Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer's disease, and dementia with Lewy bodies2010
Dr Tuomo Polvikoski
α-Synuclein pathology in the spinal cord autonomic nuclei associates with α-synuclein pathology in the brain: a population-based Vantaa 85+ study2010
Dr Tuomo Polvikoski
Apolipoprotein E (APOE) and lipoprotein lipase (LPL) gene variants and carotid atherosclerotic lesions in the oldest old: A population-based autopsy study2009
Professor Raj Kalaria
Dr Timo Erkinjuntti
Dr Tuomo Polvikoski
Frontal lobe white matter changes are associated with neurofibrillary pathology in the oldest old2009
Dr Tuomo Polvikoski
Neuropathologic findings of dementia with Lewy bodies (DLB) in a population based Vantaa 85+ Study2009
Yumi Yamamoto
Dr Masafumi Ihara
Carina Tham
Janet Slade
Arthur Oakley
et al.
Neuropathological Correlates of Temporal Pole White Matter Hyperintensities in CADASIL2009
Dr Tuomo Polvikoski
Neurofibrillary tau pathology modulated by genetic variation of a-synuclein.2008
Dr Tuomo Polvikoski
Senile systemic amyloidosis affects 25% of the very aged and associates with genetic variation in alpha2-macroglobulin and tau: A population-based autopsy study2008
Dr Masafumi Ihara
Dr Tuomo Polvikoski
Roslyn Hall
Janet Slade
Arthur Oakley
et al.
Severity of myelin loss in the frontal and temporal lobes in age-related dementias2008
Professor Raj Kalaria
Dr Tuomo Polvikoski
Dr Christopher Morris
A novel frontotemporal dementia in a South African family: neuropathological findings2007
Dr Tuomo Polvikoski
Professor Tim Griffiths
Dr Daniel Birchall
Professor Patrick Chinnery
Argyrophilic grain disease as part of the fragile-X premutation syndrome2007
Dr Tuomo Polvikoski
Atrial fibrillation, stroke, and cognition - A longitudinal population-based study of people aged 85 and older2007
Dr Kelvin Lee
Dr Tuomo Polvikoski
Dr Daniel Birchall
Dr Mauro Santibanez Koref
Emeritus Professor David Mendelow
et al.
Genome-wide cell-specific gene expression analysis identifies the involvement of the adipocytokine signalling pathway in atherosclerotic plaque rupture2007
Dr Tuomo Polvikoski
Reappraisal of a Consecutive Autopsy Series of Patients with Primary Degenerative Dementia of Alzheimer type: Lewy body pathology2007
Dr Tuomo Polvikoski
Reappraisal of a consecutive autopsy series of patients with primary degenerative dementia: Lewy-related pathology2007
Dr Tuomo Polvikoski
Professor Raj Kalaria
Dr Timo Erkinjuntti
The significance of medial temporal lobe atrophy: A postmortem MRI study in the very old2007
Dr Tuomo Polvikoski
Alzheimerin taudin patogeneesi (In Finnish; English translation: Pathogenesis of Alzheimer's disease)2006
Dr Tuomo Polvikoski
Professor Raj Kalaria
Emeritus Professor Robert Perry
Veronica Miller
Professor Rose Anne Kenny
et al.
Carotid sinus hypersensitivity associated with focal alpha-synucleinopathy of the autonomic nervous system2006
Dr Kelvin Lee
Dr Tuomo Polvikoski
Dr Daniel Birchall
Dr Mauro Santibanez Koref
Emeritus Professor David Mendelow
et al.
Genome-wide cell-specific approach to atherosclerotic plaque rupture identifies the involvement of the adipocytokine signaling pathway2006
Dr Tuomo Polvikoski
Incidence of dementia in very elderly individuals: A clinical, neuropathological and molecular genetic study2006
Dr Tuomo Polvikoski
Senile systemic amyloidosis, cerebral amyloid angiopathy, and dementia in a very old Finnish population2006
Dr Tuomo Polvikoski
Cerebral amyloid angiopathy in a 95+cohort: complement activation and apolipoprotein E (ApoE) genotype2005
Dr Tuomo Polvikoski
Chromosome 21 BACE2 haplotype associates with Alzheimer's disease: A two-stage study2005
Dr Tuomo Polvikoski
[PhD Thesis] Alzheimer's disease and apolipoprotein E. A prospective, population-based molecular genetic and neuropathological study of individuals aged 85 years or more2004
Dr Tuomo Polvikoski
HR MAS 1H MR spectroscopy reveal significantly altered neuronal metabolite profiles in CLN1 but not in CLN32004
Professor Raj Kalaria
Professor Rose Anne Kenny
Dr Clive Ballard
Emeritus Professor Robert Perry
Dr Tuomo Polvikoski
et al.
Towards defining the neuropathological substrates of vascular dementia2004
Dr Tuomo Polvikoski
Familial motor neurone disease with dementia: phenotypic variation and cerebellar pathology2003
Dr Tuomo Polvikoski
ApoE ε3-Haplotype Modulates Alzheimer's Beta-Amyloid Deposition in the Brain2002
Dr Tuomo Polvikoski
Association of lipoprotein lipase Ser447Ter polymorphism with brain infarction: a population-based neuropathological study2001
Dr Tuomo Polvikoski
Does apolipoprotein E influence learning and memory in the nondemented oldest old?2001
Dr Tuomo Polvikoski
Prevalence of Alzheimer’s disease in very elderly people: a prospective neuropathological study2001
Dr Tuomo Polvikoski
Apolipoprotein E, cognitive function and dementia in a general population aged 85 years and over2000
Dr Tuomo Polvikoski
Cardiovascular risk factors and Alzheimer’s disease: a genetic association study in a population aged 85 or over2000
Dr Tuomo Polvikoski
No association between TAU haplotype and Alzheimer’s disease in population or clinic based series or in familial disease2000
Dr Tuomo Polvikoski
Alpha-2-macroglobulin: Genetic association with Alzheimer’s disease in a Finnish elderly population1999