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Browsing publications by Professor Andrew Trevelyan.

Newcastle AuthorsTitleYearFull text
Professor Andrew Trevelyan
A debate on the neuronal origin of focal seizures2023
Dr Edward Merricks
Professor Andrew Trevelyan
Professor Cathy Schevon
Cell-type specific and multiscale dynamics of human focal seizures in limbic structures2023
Dr Boubker Zaaimi
Mark Turnbull
Dr Anupam Hazra
Dr Yujiang Wang
Dr Carolina Gandara de Souza
et al.
Closed-loop optogenetic control of the dynamics of neural activity in non-human primates2023
Dr Rob Graham
Dr Laura Alberio
Dr Luciano Saieva
Dr Darren Walsh
Professor Andrew Trevelyan
et al.
Daily rhythm in cortical chloride homeostasis underpins functional changes in visual cortex excitability2023
Dr Ryley Parrish
Connie Mackenzie-Gray Scott
Dr Alex Grundmann
Dr Faye McLeod
Neela Codadu
et al.
Indirect Effects of Halorhodopsin Activation: Potassium Redistribution, Nonspecific Inhibition, and Spreading Depolarization2023
Dr Ryley Parrish
Professor Andrew Trevelyan
Optogenetic ion pumps differ with respect to the secondary pattern of K+ redistribution2023
Dr Rob Graham
Ryley Parrish
Dr Laura Alberio
Dr Emily Johnson
Professor Andrew Trevelyan
et al.
Optogenetic stimulation reveals a latent tipping point in cortical networks during ictogenesis2023
Dr Faye McLeod
Anna Dimtsi
Amy Marshall
Dr David Lewis-Smith
Dr Rhys Thomas
et al.
Altered synaptic connectivity in an in vitro human model of STXBP1 encephalopathy2022
Dr Boubker Zaaimi
Mark Turnbull
Dr Anupam Hazra
Dr Yujiang Wang
Dr Carolina Gandara De Souza
et al.
Closed-loop optogenetic control of normal and pathological network dynamics2022
Professor Andrew Trevelyan
Genetically encoded sensors for Chloride concentration2022
Connie Mackenzie-Gray Scott
Ryley Parrish
Dr Darren Walsh
Dr Claudia Racca
Professor Andrew Trevelyan
et al.
PV-specific loss of the transcriptional coactivator PGC-1α slows down the evolution of epileptic activity in an acute ictogenic model.2022
Professor Andrew Trevelyan
Ryley Parrish
Neela Codadu
Synergistic Positive Feedback Mechanisms Underlying Seizure Initiation2022
Connie Mackenzie-Gray Scott
Ryley Parrish
Professor Andrew Trevelyan
Targeting firing rate neuronal homeostasis can prevent seizures2022
Dimitrios Firfilionis
Frances Hutchings
Dr Reza Tamadoni Jahromi
Dr Darren Walsh
Mark Turnbull
et al.
A Closed-Loop Optogenetic Platform2021
Dr Andrei Ilie
Ashan Jayasekera
Christopher Cowie
Professor Andrew Trevelyan
A multiorganism pipeline for antiseizure drug discovery: Identification of chlorothymol as a novel γ-aminobutyric acidergic anticonvulsant2020
Professor Andrew Trevelyan
Chloride dynamics alter the input-output properties of neurons2020
Christoforos Papasavvas
Professor Andrew Trevelyan
Professor Marcus Kaiser
Dr Yujiang Wang
Divisive gain modulation enables flexible and rapid entrainment in a neocortical microcircuit model2020
Dr Zhijuan Wu
Professor Andrew Trevelyan
Modulation of brain cation-Cl− cotransport via the SPAK kinase inhibitor ZT-1a2020
Christoforos Papasavvas
Ryley Parrish
Professor Andrew Trevelyan
Propagating Activity in Neocortex, Mediated by Gap Junctions and Modulated by Extracellular Potassium2020
Gabrielle Schroeder
Professor Andrew Trevelyan
Dr Rob Forsyth
Professor Andrew Jackson
Dr Peter Taylor
et al.
Seizure pathways change on circadian and slower timescales in individual patients with focal epilepsy2020
Neela Codadu
Dr Rob Graham
Professor Andrew Trevelyan
Ryley Parrish
Divergent paths to seizure-like events2019
Neela Codadu
Ryley Parrish
Professor Andrew Trevelyan
Excitatory GABAergic signalling is associated with benzodiazepine resistance in status epilepticus2019
Ryley Parrish
Neela Codadu
Connie Mackenzie-Gray Scott
Professor Andrew Trevelyan
Feedforward inhibition ahead of ictal wavefronts is provided by both parvalbumin‐ and somatostatin‐expressing interneurons2019
Professor Cathy Schevon
Dr Edward Merricks
Ryley Parrish
Professor Andrew Trevelyan
Multiscale recordings reveal the dynamic spatial structure of human seizures2019
Neela Codadu
Ryley Parrish
Professor Andrew Trevelyan
Region‐specific differences and areal interactions underlying transitions in epileptiform activity2019
Ryley Parrish
Dr John Grady
Neela Codadu
Dr Claudia Racca
Professor Andrew Trevelyan
et al.
Graphical user interface for simultaneous profiling of activity patterns in multiple neuronal subclasses2018
Ryley Parrish
Neela Codadu
Dr Claudia Racca
Professor Andrew Trevelyan
Pyramidal cell activity levels affect the polarity of gene transciption changes in interneurons2018
Ryley Parrish
Dr John Grady
Neela Codadu
Professor Andrew Trevelyan
Dr Claudia Racca
et al.
Simultaneous profiling of activity patterns in multiple neuronal subclasses2018
Ryley Parrish
Professor Andrew Trevelyan
Stress-testing the brain to understand its breaking points2018
Partow Yazdani
Professor Jenny Read
Professor Roger Whittaker
Professor Andrew Trevelyan
Assessment of epilepsy using noninvasive visual psychophysics tests of surround suppression2017
Dr Yujiang Wang
Professor Andrew Trevelyan
Dr Peter Taylor
Professor Marcus Kaiser
Mechanisms underlying different onset patterns of focal seizures2017
Dr Hannah Alfonsa
Professor Jeremy Lakey
Professor Robert Lightowlers
Professor Andrew Trevelyan
Cl-out is a novel cooperative optogenetic tool for extruding chloride from neurons2016
Professor Andrew Trevelyan
Do Cortical Circuits Need Protecting from Themselves?2016
Dr Edward Merricks
Professor Andrew Trevelyan
The ictal wavefront is the spatiotemporal source of discharges during spontaneous human seizures2016
Christoforos Papasavvas
Dr Yujiang Wang
Professor Andrew Trevelyan
Professor Marcus Kaiser
Gain control through divisive inhibition prevents abrupt transition to chaos in a neural mass model2015
Professor Jenny Read
Partow Yazdani
Professor Roger Whittaker
Professor Andrew Trevelyan
Dr Ignacio Serrano-Pedraza
et al.
Moderate acute alcohol intoxication has minimal effect on surround suppression measured with a motion direction discrimination task2015
Dr Elizabeth Stoll
Professor Andrew Trevelyan
Dr Satomi Miwa
Emeritus Professor Doug Turnbull
Neural stem cells in the adult subventricular zone oxidize fatty acids to produce energy and support neurogenic activity.2015
Professor Andrew Trevelyan
Seizure localization using ictal phase-locked high gamma: A retrospective surgical outcome study2015
Dr Edward Merricks
Professor Andrew Trevelyan
Single unit action potentials in humans and the effect of seizure activity2015
Dr Hannah Alfonsa
Dr Edward Merricks
Neela Codadu
Professor Mark Cunningham
Dr Claudia Racca
et al.
The Contribution of Raised Intraneuronal Chloride to Epileptic Network Activity2015
Professor Andrew Trevelyan
Dr Edward Merricks
Dr Claudia Racca
The Role of Inhibition in Epileptic Networks2015
Partow Yazdani
Dr Ignacio Serrano-Pedraza
Professor Roger Whittaker
Professor Andrew Trevelyan
Professor Jenny Read
et al.
Two common psychophysical measures of surround suppression reflect independent neuronal mechanisms2015
Professor Graham Coates
Professor Andrew Trevelyan
Dynamically Controlled Variable-Fidelity Modelling for Aircraft Structural Design Optimisation2014
Professor Andrew Trevelyan
How inhibition influences seizure propagation2013
Professor Andrew Trevelyan
Ictal high frequency oscillations distinguish two types of seizure territories in humans2013
Professor Andrew Trevelyan
The contribution of synaptic location to inhibitory gain control in pyramidal cells2013
Professor Andrew Trevelyan
The information content of physiological and epileptic brain activity2013
Professor Andrew Trevelyan
Evidence of an inhibitory restraint of seizure activity in humans2012
Dr Nicolas Forraz
Professor Colin McGuckin
Dr Marcin Jurga
Emerita Professor Susan Lindsay
Bui Ip
et al.
In vitro modelling of cortical neurogenesis by sequential induction of human umbilical cord blood stem cells2012
Dr Marcin Jurga
Dr Nicolas Forraz
Christina Basford
Professor Andrew Trevelyan
Dr Saba Habibollah
et al.
Neurogenic Properties and a Clinical Relevance of Multipotent Stem Cells Derived from Cord Blood Samples Stored in the Biobanks2012
Professor Andrew Trevelyan
Cellular mechanisms of high frequency oscillations in epilepsy: on the diverse sources of pathological activities2011
Professor Andrew Trevelyan
Dr Denise Kirby
Dr Tora Smulders-Srinivasan
Marco Nooteboom
Professor Miles Whittington
et al.
Mitochondrial DNA mutations affect calcium handling in differentiated neurons2010
Professor Jenny Read
Professor Andrew Trevelyan
Quantal Analysis Reveals a Functional Correlation between Presynaptic and Postsynaptic Efficacy in Excitatory Connections from Rat Neocortex2010
Dr Denise Kirby
Dr Kate Rennie
Dr Tora Smulders-Srinivasan
Professor Miles Whittington
Professor Andrew Trevelyan
et al.
Transmitochondrial embryonic stem cells containing pathogenic mtDNA mutations are compromised in neuronal differentiation2009
Dr Anita Roopun
Professor Mark Cunningham
Professor Roger Whittaker
Professor Andrew Trevelyan
Dr Andrew Russell
et al.
Detecting seizure origin using basic, multiscale population dynamic measures: Preliminary findings2009
Professor Andrew Trevelyan
Imaging seizure propagation in vitro2009
Professor Andrew Trevelyan
Spatial characterization of interictal high frequency oscillations in epileptic neocortex2009
Professor Andrew Trevelyan
The Direct Relationship between Inhibitory Currents and Local Field Potentials2009
Professor Andrew Trevelyan
An experimentally induced duplication of retinotopic mapping within the hamster primary visual cortex2007
Professor Andrew Trevelyan
Feedforward inhibition contributes to the control of epileptiform propagation speed2007
Professor Andrew Trevelyan
Is there a common origin to surround-inhibition as seen through electrical activity versus hemodynamic changes? Focus on "duration-dependent response in SI to vibrotactile stimulation in squirrel monkey"2007
Professor Andrew Trevelyan
Professor Miles Whittington
The source of afterdischarge activity in neocortical tonic-clonic epilepsy2007
Professor Andrew Trevelyan
Modular propagation of epileptiform activity: Evidence for an inhibitory veto in neocortex2006