Browsing publications by Professor John Lunec

Newcastle AuthorsTitleYearFull text
Dr Nicholas Bown
Professor John Lunec
Professor Deborah Tweddle
Influence of segmental chromosome abnormalities on survival in children over the age of 12 months with unresectable localised peripheral neuroblastic tumours without MYCN amplification2015
Dr Lindi Chen
Professor Herbie Newell
Professor John Lunec
Professor Deborah Tweddle
Pre-clinical evaluation of the MDM2-p53 antagonist RG7388 alone and in combination with chemotherapy in neuroblastoma2015
Alex Liu
Dr Catherine Drummond
Professor Jane Endicott
Professor Bernard Golding
Professor Roger Griffin
et al.
An X-ray crystal structure-based understanding of the inhibition of the MDM2-p53 protein-protein interaction by isoindolinones2014
Dr Emma Bell
Dr Frida Ponthan
Claire Whitworth
Professor Deborah Tweddle
Professor John Lunec
et al.
COX2 expression in neuroblastoma increases tumorigenicity but does not affect cell death in response to the COX2 inhibitor celecoxib2014
Dr Andrey Zaytsev
Dr Barry Dodd
Professor Bernard Golding
Professor Roger Griffin
Dr Xiaohong Lu
et al.
Searching for Dual Inhibitors of the MDM2-p53 and MDMX-p53 Protein-Protein Interaction by a Scaffold-Hopping Approach2014
Dr Lindi Chen
Dr Yan Zhao
Dr Gail Halliday
Philip Berry
Professor Herbie Newell
et al.
Structurally diverse MDM2-p53 antagonists act as modulators of MDR-1 function in neuroblastoma2014
Professor John Lunec
The clinical development of p53-reactivating drugs in sarcomas - charting future therapeutic approaches and understanding the clinical molecular toxicology of Nutlins2014
Annalisa Bertoli
Santosh Adhikari
Dr Suzannah Harnor
Dr Yan Zhao
Professor John Lunec
et al.
Validation studies with small-molecule modulators of the MDM2/MDMX-p53 binding interaction2014
Dr Tim Blackburn
Christopher Coxon
Dr Xiaohong Lu
Professor Bernard Golding
Professor Roger Griffin
et al.
Diaryl- and triaryl-pyrrole derivatives: inhibitors of the MDM2-p53 and MDMX-p53 protein-protein interactions2013
Nidal Boulos
Dr Michael Tilby
Professor Deborah Tweddle
Professor John Lunec
Identification and characterisation of STMN4 and ROBO2 gene involvement in neuroblastoma cell differentiation2013
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