Browsing publications by Professor John Lunec

Newcastle AuthorsTitleYearFull text
Maryam Zanjirband Zanjirband
Professor Nicola Curtin
Professor John Lunec
Combination treatment with rucaparib (Rubraca) and MDM2 inhibitors, Nutlin-3 and RG7388, has synergistic and dose reduction potential in ovarian cancer2017
Dr Aiste McCormick
Gavin Cuthbert
Dr Rachel O'Donnell
Dr Brian Wilson
Huw Thomas
et al.
Functional characterisation of a novel ovarian cancer cell line, NUOC-12017
Dr Catherine Drummond
Arman Esfandiari
Dr Xiaohong Lu
Dr Claire Hutton
Dr Jennifer Jackson
et al.
TP53 mutant MDM2-amplified cell lines selected for resistance to MDM2-p53 binding antagonists retain sensitivity to ionizing radiation2016
Arman Esfandiari
Dr Sirintra Nakjang
Professor John Lunec
Chemical Inhibition of Wild-Type p53-Induced Phosphatase 1 (WIP1/PPM1D) by GSK2830371 Potentiates the Sensitivity to MDM2 Inhibitors in a p53-Dependent Manner2016
Dr Ioannis Kotsopoulos
Dr Asima Mukhopadhyay
Professor John Lunec
Professor Nicola Curtin
Ali Kucukmetin
et al.
IN VITRO SINGLE AGENT RUCAPARIB CYTOTOXICITY AND CISPLATIN CHEMO-POTENTIATION IN CERVICAL CANCER CELL LINES2016
Dr Ian Logan
Dr Urszula McClurg
Dr Dominic Jones
Daniel O'Neill
Dr Fadhel Shaheen
et al.
Nutlin-3 inhibits androgen receptor-driven c-FLIP expression, resulting in apoptosis of prostate cancer cells2016
Dr Ioannis Kotsopoulos
Ali Kucukmetin
Dr Asima Mukhopadhyay
Professor John Lunec
Professor Nicola Curtin
et al.
Poly(ADP-Ribose) Polymerase in Cervical Cancer Pathogenesis Mechanism and Potential Role for PARP Inhibitors2016
Maryam Zanjirband Zanjirband
Professor Richard Edmondson
Professor John Lunec
Pre-clinical efficacy and synergistic potential of the MDM2-p53 antagonists, Nutlin-3 and RG7388, as single agents in combined treatment with cisplatin in ovarian cancer2016
Dr Jeffry Hogg
Professor Derek Manas
Dr Daniela Lee
Dr Petra Dildey
Professor John Lunec
et al.
Surgical outcome and patterns of recurrence for retroperitoneal sarcoma at a single centre.2016
Dr Laura Woodhouse
Clark Crawford
Dr Scott Marshall
Dr Nicholas Bown
Dr Elaine Willmore
et al.
Assessment and targeting of the MDM2-p53 network in CLL2015
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