Browsing publications by Lan-zhen Wang

Newcastle AuthorsTitleYear
Dr Benoit Carbain
Dr Allyson Campbell
Dr Celine Cano
Professor Jane Endicott
Professor Bernard Golding
et al.
8-Substituted O-6-Cyclohexylmethylguanine CDK2 Inhibitors: Using Structure-Based Inhibitor Design to Optimize an Alternative Binding Mode2014
Dr Benoit Carbain
Christopher Coxon
Honorine Lebraud
Christopher Matheson
David Turner
et al.
2-arylamino-6-ethynylpurines as Potent Irreversible Inhibitors of the Mitotic Kinase Nek22012
Dr Sonja Baumli
Dr Alison Hole
Lan-zhen Wang
Professor Martin Noble
Professor Jane Endicott
et al.
The CDK9 Tail Determines the Reaction Pathway of Positive Transcription Elongation Factor b2012
Elisa Meschini
Professor Jane Endicott
Professor Bernard Golding
Dr Ian Hardcastle
Professor Herbie Newell
et al.
Design and synthesis of dual CDK2 and CDK7 inhibitors2010
Nicola Johnson
Dr Johanne Bentley
Lan-zhen Wang
Professor Herbie Newell
Professor Craig Robson
et al.
Pre-clinical evaluation of cyclin-dependent kinase 2 and 1 inhibition in anti-estrogen-sensitive and resistant breast cancer cells2010
Dr Francesco Marchetti
Dr Celine Cano
Professor Nicola Curtin
Professor Bernard Golding
Professor Roger Griffin
et al.
Synthesis and biological evaluation of 5-substituted O4-alkylpyrimidines as CDK2 inhibitors2010
Dr Christopher Wong
Professor Roger Griffin
Dr Ian Hardcastle
Dr Julian Scott Northen
Lan-zhen Wang
et al.
Synthesis of sulfonamide-based kinase inhibitors from sulfonates by exploiting the abrogated SN2 reactivity of 2,2,2-trifluoroethoxysulfonates2010
Huw Thomas
Dr Kappusamy Saravanan
Lan-zhen Wang
Mei Lin
Dr Julian Scott Northen
et al.
Preclinical evaluation of a novel pyrimidopyrimidine for the prevention of nucleoside and nucleobase reversal of antifolate cytotoxicity2009
Professor Herbie Newell
Huw Thomas
Lan-zhen Wang
Dr Celine Roche
Dr Ian Hardcastle
et al.
[abstract] Preclinical in vitro and in vivo evaluation of the cyclin dependent kinase 2 inhibitor NU6102 and a water pro-drug NU63012008
Lan-zhen Wang
Professor Nicola Curtin
Professor Herbie Newell
Transient treatment with CDK inhibitors eliminates proliferative potential even when their abilities to evoke apoptosis and DNA damage are blocked2008
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