Publications by Dr Nick Watkins - ePrints

Browsing publications by Dr Nick Watkins.

Newcastle Authors	Title	Year
Matthew Eastham Andria Pelava Dr Graeme Wells Justine Lee Isabella Lawrence et al.	The induction of p53 correlates with defects in the production, but not the levels, of the small ribosomal subunit and stalled large ribosomal subunit biogenesis	2023
Dr Nick Watkins	Association of snR190 snoRNA chaperone with early pre-60S particles is regulated by the RNA helicase Dbp7 in yeast	2021
Dr Robert van Nues Dr Claudia Schneider Dr Nick Watkins	RNA helicase-mediated regulation of snoRNP dynamics on pre-ribosomes and rRNA 2'-O-methylation	2021
Kate Sloan Andy Knox Dr Graeme Wells Dr Claudia Schneider Dr Nick Watkins et al.	Interactions and activities of factors involved in the late stages of human 18S rRNA maturation	2019
Dr Graeme Wells Franziska Weichmann Kate Sloan David Colvin Dr Nick Watkins et al.	The ribosome biogenesis factor yUtp23/hUTP23 coordinates key interactions in the yeast and human pre-40S particle and hUTP23 contains an essential PIN domain	2017
Dr Nick Watkins	Unusual C'/D' motifs enable box C/D snoRNPs to modify multiple sites in the same rRNA target region	2017
Andria Pelava Dr Claudia Schneider Dr Nick Watkins	The importance of ribosome production, and the 5S RNP–MDM2 pathway, in health and disease	2016
Dr Graeme Wells Franziska Weichmann David Colvin Kate Sloan Dr Nick Watkins et al.	The PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans	2016
Dr Graeme Wells Franziska Weichmann David Colvin Kate Sloan Dr Nick Watkins et al.	The PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans (vol 44, pg 5399, 2016) [Corrigendum]	2016
Eileen Leung Dr Claudia Schneider Fu Yan Hatem Mohi El Din Dr Victoria Doronina et al.	Integrity of SRP RNA is ensured by La and the nuclear RNA quality control machinery	2014
Katherine Sloan Dr Nick Watkins	The association of late-acting snoRNPs with human pre-ribosomal complexes requires the RNA helicase DDX21	2014
Kate Sloan Dr Claudia Schneider Dr Nick Watkins	The roles of SSU processome components and surveillance factors in the initial processing of human ribosomal RNA	2014
Kate Sloan Dr Nick Watkins	Both endonucleolytic and exonucleolytic cleavage mediate ITS1 removal during human ribosomal RNA processing	2013
Kate Sloan Dr Nick Watkins	The 5S RNP couples p53 homeostasis to ribosome biogenesis and nucleolar stress	2013
Kate Sloan Dr Claudia Schneider Dr Nick Watkins	Comparison of the yeast and human nuclear exosome complexes	2012
Dr Amy Erhorn Andy Knox Dr Nick Watkins	Nucleolar disruption leads to the spatial separation of key 18S rRNA processing factors	2012
Dr Claudia Schneider Dr Nick Watkins	Proofreading of pre-40S ribosome maturation by a translation initiation factor and 60S subunits	2012
Dr Nick Watkins	The box C/D and H/ACA snoRNPs: key players in the modification, processing and the dynamic folding of ribosomal RNA	2012
Andy Knox Dr Kenneth McKeegan Charles Debieux Dr Hannah Richardson Dr Nick Watkins et al.	A weak C’ box renders U3 snoRNA levels dependent on hU3-55K binding	2011
Dr Robert Van Nues Kate Sloan Matthew Chicken Dr Nick Watkins	Box C/D snoRNP catalysed methylation is aided by additional pre-rRNA base-pairing	2011
Dr Nick Watkins	Evolution of box C/D RNP structure and function	2011
Dr Nick Watkins	The Spatial-Functional Coupling of Box C/D and C'/D' RNPs Is an Evolutionarily Conserved Feature of the Eukaryotic Box C/D snoRNP Nucleotide Modification Complex	2011
Dr Nick Watkins	A novel Nop5-sRNA interaction that is required for efficient archaeal box C/D sRNP formation	2010
Dr Paul Dean Jonathan Scott Andy Knox Sabine Quitard Dr Nick Watkins et al.	The Enteropathogenic E. coli Effector EspF Targets and Disrupts the Nucleolus by a Process Regulated by Mitochondrial Dysfunction	2010
Dr Amy Erhorn Andy Knox Dr Nick Watkins	A Novel Small-Subunit Processome Assembly Intermediate That Contains the U3 snoRNP, Nucleolin, RRP5, and DBP4	2009
Dr Kenneth McKeegan Charles Debieux Dr Nick Watkins	Evidence that the AAA⁺ Proteins TIP48 and TIP49 Bridge Interactions between 15.5K and the Related NOP56 and NOP58 Proteins during Box C/D snoRNP Biogenesis	2009
Dr Claudia Schneider Dr Nick Watkins	Minor spliceosome components are predominantly localized in the nucleus	2008
Dr Kenneth McKeegan Charles Debieux Dr Nick Watkins	A dynamic scaffold of pre-snoRNP factors facilitates human box C/D snoRNP assembly	2007
Dr Heather Lamb Paul Thompson Dr Nick Watkins Professor Alastair Hawkins	Functional analysis of the GTPases EngA and YhbZ encoded by Salmonella typhimurium	2007
Dr Nick Watkins	Involvement of nuclear import and export factors in U8 box C/D snoRNP biogenesis	2007
Dr Nick Watkins	Ongoing U snRNP biogenesis is required for the integrity of Cajal bodies	2006
Dr Nick Watkins	Protein-protein and protein-RNA contacts both contribute to the 15.5K-mediated assembly of the U4/U6 snRNP and the box C/D snoRNPs	2006
Dr Nick Watkins Dr Claudia Schneider	Assembly and Maturation of the U3 snoRNP in the Nucleoplasm in a Large Dynamic Multiprotein Complex	2004
Dr Nick Watkins	Role of pre-rRNA base pairing and 80S complex formation in subnucleolar localization of the U3 snoRNP	2004
Dr Nick Watkins	Conserved Stem II of the Box C/D Motif Is Essential for Nucleolar Localization and Is Required, Along with the 15.5K Protein, for the Hierarchical Assembly of the Box C/D snoRNP	2002
Dr Nick Watkins	The hU3-55K Protein Requires 15.5K Binding to the Box B/C Motif as Well as Flanking RNA Elements for Its Association with the U3 Small Nucleolar RNA in Vitro	2002
Dr Nick Watkins	A common core RNP structure shared between the small nucleolar box C/D RNPs and the spliceosomal U4 snRNP	2000