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Browsing publications by Professor Alexander Burkle.

Newcastle AuthorsTitleYearFull text
Ragen Pfeiffer
Alan Leake
Dr Michelle Muller
Emeritus Professor Thomas Kirkwood
Professor Alexander Burkle
et al.
A modified and automated version of the 'Fluorimetric Detection of Alkaline DNA Unwinding' method to quantify formation and repair of DNA strand breaks2009
Yonghua Zhang
Professor Alexander Burkle
Genetic heterogeneity versus molecular analysis of prion susceptibility in neuroblasma N2a sublines2008
Ragen Pfeiffer
Dr Michelle Muller
Alan Leake
Emeritus Professor Thomas Kirkwood
Professor Alexander Burkle
et al.
An automated version of the fluorescence-detected alkaline DNA-unwinding (FADU) assay to measure DNA strand breaks and DNA repair2007
Professor Doug Gray
Professor Alexander Burkle
SENS and the polarization of aging-related research2006
Ragen Pfeiffer
Dr Michelle Muller
Alan Leake
Emeritus Professor Thomas Kirkwood
Professor Alexander Burkle
et al.
An automated version of the fluorescence-detected alkaline DNA-unwinding (FADU) assay to measure DNA strand breaks and DNA repair2005
Professor Alexander Burkle
Dr Marie-Laure Muiras
Expression of a dominant negative version of poly(ADP-ribose) polymerase-1 in basal skin keratinocytes of transgenic mice potentiates alkylationanduced in skin tumour formation2005
Ragen Pfeiffer
Alan Leake
Professor Alexander Burkle
L-selegiline potentiates cellular poly (ADP-ribose) formation induced by DNA damage2004
Professor Alexander Burkle
Dr Marie-Laure Muiras
Poly(ADP-ribosyl)ation and aging2004
Ragen Pfeiffer
Alan Leake
Professor Alexander Burkle
L-selegiline potentiates the cellular poly(ADP-ribosyl)ation response to ionizing radiation2003
Professor Alexander Burkle
Emeritus Professor Thomas Kirkwood
Poly(ADP-ribose) polymerase-1 is a survival factor for radiation-exposed intestinal epithelial stem cells in vivo2003
Yonghua Zhang
Professor Alexander Burkle
Up-regulation of cathepsin B and cathepsin L activities in scrapie-infected mouse Neuro2a cells2003
Professor Alexander Burkle
In memoriam - Bernard Strehler - genomic instability in ageing: a persistent challenge2002
Professor Alexander Burkle
Increase in de novo HBV DNA integrations in response to oxidative DNA damage or inhibition of poly(ADP-ribosyl)ation2002
Professor Alexander Burkle
In-situ analysis of cellular poly(ADP-ribose) production in scrapie-infected mouse neuroblastoma cells2002
Professor Alexander Burkle
Interference by toxic metal ions with DNA repair processes and cell cycle control: Molecular mechanisms2002
Professor Alexander Burkle
Interference by toxic metal ions with zinc-dependent proteins involved in maintaining genomic stability2002
Professor Alexander Burkle
L-selegiline potentiates cellular poly(ADP-ribose) formation induced by DNA damage2002
Professor Alexander Burkle
Alan Leake
Dr Marie-Laure Muiras
Ragen Pfeiffer
Poly(ADP-ribose) polymerase-1, DNA repair and mammalian longevity2002
Professor Alexander Burkle
Poly(ADP-ribosyl)ation, genomic instability and mammalian longevity2002
Professor Alexander Burkle
Reduced poly(ADP-ribosyl)ation in lymphocytes of laryngeal cancer patients: Results of a case-control study2002
Professor Alexander Burkle
Role of poly(ADP-ribosyl)ation in DNA-PKcs-independent V(D)J recombination2002
Professor Alexander Burkle
Mechanisms of ageing2001
Professor Alexander Burkle
PARP-1: a regulator of genomic stability linked with mammalian longevity2001
Professor Alexander Burkle
Physiology and pathophysiology of poly(ADP-ribosyl)ation2001
Professor Alexander Burkle
Poly(APD-ribosyl)ation, a DNA damage-driven protein modification and regulator of genomic instability2001
Professor Thomas von Zglinicki
Professor Alexander Burkle
Emeritus Professor Thomas Kirkwood
Stress, DNA damage and ageing - An integrative approach2001
Professor Alexander Burkle
Comparative characterisation of poly(ADP-ribose) polymerase-1 from two mammalian species with different life span2000
Professor Alexander Burkle
Negative regulation of alkylation-induced sister-chromatid exchange by poly(ADP-ribose) polymerase-1 activity2000
Professor Alexander Burkle
Dr Marie-Laure Muiras
New polymorphisms in the human poly(ADP-ribose) polymerase-1 coding sequence: Lack of association with longevity or with increased cellular poly(ADP-ribosyl)ation capacity2000
Professor Alexander Burkle
Poly(ADP-ribosyl)ation, genomic instability, and longevity2000
Professor Alexander Burkle
Poly(ADP-ribosyl)ation, genomic instability, and longevity2000
Professor Alexander Burkle
Poly(ADP-ribosyl)ation: A posttranslational protein modification linked with genome protection and mammalian longevity2000
Professor Alexander Burkle
Quantitative assessment of bleomycin-induced poly(ADP-ribosyl)ation in human lymphocytes by immunofluorescence and image analysis2000
Professor Alexander Burkle
Detection of poly(ADP-ribose) synthesis in Drosophila testes upon gamma-irradiation1999
Professor Alexander Burkle
Overexpression of dominant negative PARP interferes with tumor formation of HeLa cells in nude mice: evidence for increased tumor cell apoptosis in vivo1999
Professor Alexander Burkle
Poly(ADP-ribose) immunostaining to detect apoptosis induced by a neurotoxic fragment of prion protein1999
Ragen Pfeiffer
Professor Alexander Burkle
Quantitative nonisotopic immuno-dot-blot method for the assessment of cellular poly(ADP-ribosyl)ation capacity1999
Professor Alexander Burkle
Reactive oxygen species participate in mdr1b mRNA and P-glycoprotein overexpression in primary rat hepatocyte cultures1999
Professor Alexander Burkle
Selective loss of poly(ADP-ribose) and the 85-kDa fragment of poly(ADP-ribose) polymerase in nucleoli during alkylation-induced apoptosis of HeLa cells1999
Professor Alexander Burkle
Trans-dominant inhibition of poly(ADP-ribosyl)ation potentiates alkylation-induced shuttle-vector mutagenesis in Chinese hamster cells1999