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Browsing publications by Professor Brendan Kenny.

Newcastle AuthorsTitleYearFull text
Dr Paul Dean
Sabine Quitard
Dr David Bulmer
Professor Brendan Kenny
Cultured enterocytes internalise bacteria across their basolateral surface for, pathogen-inhibitable, trafficking to the apical compartment2015
Professor Brendan Kenny
Nck adaptors, besides promoting N-WASP mediated actin-nucleation activity at pedestals, influence the cellular levels of enteropathogenic Escherichia coli Tir effector2014
Dr Paul Dean
Professor Brendan Kenny
A bacterial encoded protein induces extreme multinucleation and cell-cell internalization in intestinal cells2013
Professor Brendan Kenny
Dr Paul Dean
Do Caco-2 subclones provide more appropriate in vitro models for understanding how human enteric pathogens cause disease?2013
Dr Paul Dean
Lorna Young
Sabine Quitard
Professor Brendan Kenny
Insights into the Pathogenesis of Enteropathogenic E. coli Using an Improved Intestinal Enterocyte Model2013
Dr Paul Dean
Professor Brendan Kenny
Cell-surface nucleolin is sequestered into EPEC microcolonies and may play a role during infection2011
Dr Marie-Helene Ruchaud
Professor Brendan Kenny
Proteasome-independent degradation of canonical NFκB complex components by the NleC protein of pathogenic Escherichia coli2011
Dr Marie-Helene Ruchaud
Dr Paul Dean
Professor Brendan Kenny
The Enteropathogenic E. coli (EPEC) Tir Effector Inhibits NF-κB Activity by Targeting TNFα Receptor-Associated Factors2011
Professor Brendan Kenny
PKA-mediated phosphorylation of EPEC-Tir at serine residues 434 and 463: A novel pathway in regulating Rac1 GTPase function2010
Dr Paul Dean
Sabine Quitard
Professor Brendan Kenny
The bacterial effectors EspG and EspG2 induce a destructive calpain activity that is kept in check by the co-delivered Tir effector2010
Dr Paul Dean
Jonathan Scott
Andy Knox
Sabine Quitard
Dr Nick Watkins
et al.
The Enteropathogenic E. coli Effector EspF Targets and Disrupts the Nucleolus by a Process Regulated by Mitochondrial Dysfunction2010
Dr David Saunders
Dr Paul Dean
Professor Brendan Kenny
Judith Parkhill
Complete Genome Sequence and Comparative Genome Analysis of Enteropathogenic Escherichia coli O127:H6 Strain E2348/692009
Professor Brendan Kenny
Dual infection system identifies a crucial role for PKA-mediated serine phosphorylation of the EPEC-Tir-injected effector protein in regulating Rac1 function2009
Professor Brendan Kenny
Host-microbe interactions: bacteria2009
Dr Paul Dean
Professor Brendan Kenny
The effector repertoire of enteropathogenic E-coli: ganging up on the host cell2009
Professor Brendan Kenny
Dual infection of mammalian cells provides novel insights into injected bacterial effector protein function2008
Dr Marie-Helene Ruchaud
Professor Brendan Kenny
Enteropathogenic Escherichia coli (EPEC) inactivate innate immune responses prior to compromising epithelial barrier function2007
Professor Brendan Kenny
Tir phosphorylation and Nck/N-WASP recruitment by enteropathogenic and enterohaemorrhagic Escherichia coli during ex vivo colonization of human intestinal mucosa is different to cell culture models2007
Dr Paul Dean
Professor Brendan Kenny
Potent diarrheagenic mechanism mediated by the cooperative action of three enteropathogenic Escherichia coli-injected effector proteins2006
Professor Brendan Kenny
The enteropathogenic Escherichia coli (EPEC) Map effector is imported into the mitochondrial matrix by the TOM/Hsp70 system and alters organelle morphology2006
Sabine Quitard
Dr Paul Dean
Professor Brendan Kenny
The enteropathogenic Escherichia coli EspF effector molecule inhibits PI-3 kinase-mediated uptake independently of mitochondrial targeting2006
Dr David Miller
Sabine Quitard
Dr Paul Dean
Professor Brendan Kenny
Enteropathogenic Escherichia coli (EPEC) effector-mediated suppression of antimicrobial nitric oxide production in a small intestinal epithelial model system2005
Dr Paul Dean
Professor Brendan Kenny
EPEC's weapons of mass subversion2005
Dr Paul Dean
Professor Brendan Kenny
Intestinal barrier dysfunction by enteropathogenic Escherichia coli is mediated by two effector molecules and a bacterial surface protein2004
Professor Brendan Kenny
CesT is a bivalent enteropathogenic Escherichia coli chaperone required for translocation of both Tir and Map2003
Dr Mark Banfield
Dr David Scott
Professor Brendan Kenny
Effect of protein kinase-A mediated phosphorylation on the structure and association properties of the enteropathogenic Escherichia coli Tir virulence protein2003
Professor Brendan Kenny
Enteropathogenic Escherichia coli (EPEC) and its effector molecules2003
Dr Sonia Pellegrini
Professor Brendan Kenny
Synergistic roles for the Map and Tir effector molecules in mediating uptake of enteropathogenic Escherichia coli (EPEC) into non-phagocytic cells2003
Professor Brendan Kenny
Co-ordinate regulation of distinct host signalling pathways by multifunctional enteropathogenic Escherichia coli effector molecules2002
Professor Brendan Kenny
Enteropathogenic E. coli - a crafty subversive little bug2002
Professor Brendan Kenny
Mechanism of action of EPEC Type III effector molecules2002
Professor Brendan Kenny
Enteropathogenic Escherichia coli (EPEC) Tir Receptor Molecule Does Not Undergo Full Modification When Introduced into Host Cells by EPEC-Independent Mechanisms2001
Professor Brendan Kenny
Phosphoserine modification of the enteropathogenic Escherichia coli Tir molecule is required to trigger conformational changes in Tir and efficient pedestal elongation2001
Professor Brendan Kenny
Role of sipA in the early stages of Salmonella typhimurium entry into epithelial cells2001
Professor Brendan Kenny
The enterohaemorrhagic E. coli (serotype O157:H7) Tir molecule is not functionally interchangeable for its enteropathogenic E. coli (serotype O127:H6) homologue2001
Professor Brendan Kenny
Targeting of an enteropathogenic Escherichia coli (EPEC) effector protein to host mitochondria2000
Professor Brendan Kenny
Enteropathogenic Escherichia coli inhibits phagocytosis1999
Professor Brendan Kenny
Enteropathogenic Escherichia coli inhibits phagocytosis1999
Professor Brendan Kenny
Type III secretion-dependent haemolytic activity of enteropathogenic Escherichia coli (EPEC)1999