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Browsing publications by Elizabeth Matheson.

Newcastle AuthorsTitleYearFull text
Lucy Gentles
Bojidar Goranov
Elizabeth Matheson
Dr Ashleigh Herriott
Dr Angelika Kaufmann
et al.
Exploring the frequency of Homologous Recombination DNA Repair Dysfunction in Multiple Cancer Types2019
Zach Dixon
Dr Lindsay Nicholson
Elizabeth Matheson
Dr Paul Sinclair
Professor Christine Harrison FRCPath FMedSci
et al.
CREBBP knockdown enhances RAS/RAF/MEK/ERK signaling in Ras pathway mutated acute lymphoblastic leukemia but does not modulate chemotherapeutic response2017
Professor Julie Irving
Dr Amir Enshaei
Dr Amy Erhorn
Lynne Minto
Claire Schwab
et al.
Integration of genetic and clinical risk factors improves prognostication in relapsed childhood B-cell precursor acute lymphoblastic leukaemia2016
Dr Ganiy Abdulrahman
Elizabeth Matheson
Dr Yvette Drew
Professor Nicola Curtin
Dr Asima Mukhopadhyay
et al.
Investigating PARP inhibitor sensitisation by hyperthermia and HSP90 inhibition2016
Elizabeth Matheson
Dr Mo Salehan
Dr Asima Mukhopadhyay
Professor Nicola Curtin
Dr Yvette Drew
et al.
Preclinical studies of the PARP inhibitor olaparib in combination with imatinib in BRCA stratified ovarian cancer2016
Dr Sarra Ryan
Elizabeth Matheson
Dr Paul Sinclair
Dr Matthew Bashton
Claire Schwab
et al.
The role of the RAS pathway in iAMP21-ALL2016
Dr Lindsay Nicholson
Elizabeth Matheson
Lynne Minto
Christopher Keilty
Maryna Sanichar
et al.
Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re-sensitization by JNK inhibition2015
Professor Julie Irving
Elizabeth Matheson
Helen Blair
Marian Case
Isabella Swidenbank
et al.
Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition. Blood. 2014;124(23):3420-34302015
Professor Julie Irving
Elizabeth Matheson
Dr Helen Blair
Marian Case
Isabella Swidenbank
et al.
Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition2014
Dr Lindsay Nicholson
Elizabeth Matheson
Lynne Minto
Marian Case
Maryna Sanichar
et al.
Casitas B lymphoma mutations in childhood acute lymphoblastic leukemia2012
Dr Lindsay Nicholson
Charlotte Evans
Elizabeth Matheson
Lynne Minto
Christopher Keilty
et al.
Quantitative Proteomic Analysis Reveals Maturation As a Mechanism Underlying Glucocorticoid Resistance in Childhood Acute Lymphoblastic Leukemia and PAX5 As a Re-Sensitising Therapeutic Target2011
Dr Sarra Ryan
Dr Vikki Rand
Claire Schwab
Heather Morrison
Elizabeth Matheson
et al.
Ras Signalling Pathway and Novel Target Genes Related to Down Syndrome Contribute to the Development of B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) in iAMP21 Patients2011
Dr Amy Peasland
Elizabeth Matheson
Dr Andrew Hall
Professor Julie Irving
Alternative splicing of hMLH1 in childhood acute lymphoblastic leukaemia and characterisation of the variably expressed Δ9/10 isoform as a dominant negative species2010
Elizabeth Matheson
Lynne Minto
Dr Andrew Hall
Professor Julie Irving
Mismatch repair and the downstream target genes, PAX5 and Ikaros, in childhood acute lymphoblastic leukemia2010
Dr Lindsay Nicholson
Elizabeth Matheson
Lynne Minto
Christopher Keilty
Dr Andrew Hall
et al.
Quantitative Proteomic Analysis Implicates An Altered B-Cell Differentiation State as a Mechanism Underlying GC-Resistance in An Acute Lymphoblastic Leukaemia (ALL) Cell Line Model2009
Elizabeth Matheson
Lynne Minto
Professor Anthony Moorman
Dr Andrew Hall
Professor Julie Irving
et al.
Heterogeneous breakpoints target PAX5 in acute lymphoblastic leukaemia patients with dicentric chromosomes2008
Elizabeth Matheson
Mike Cole
Dr Bridget Wilkins
Dr Andrew Hall
Mismatch repair defects in childhood acute lymphoblastic leukaemia at diagnosis and relapse2008
Marian Case
Elizabeth Matheson
Lynne Minto
Dr Nicholas Bown
Professor Simon Bailey
et al.
Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia2008
Marian Case
Elizabeth Matheson
Lynne Minto
Professor Christine Harrison FRCPath FMedSci
Dr Nicholas Bown
et al.
Somatic mutation of genes impacting on the RAS-RAF-MEK-ERK pathway is the most common genetic abnormality in childhood acute lymphoblastic leukaemia, is implicated in disease progression and provides a rationale for therapeutic targeting2008
Elizabeth Matheson
Professor Anthony Moorman
Dr Andrew Hall
Professor Christine Harrison FRCPath FMedSci
Professor Julie Irving
et al.
Variable breakpoints target PAX5 in patients with dicentric chromosomes: A model for the basis of unbalanced translocations in cancer2008
Elizabeth Matheson
Dr Linda Hogarth
Marian Case
Professor Julie Irving
Dr Andrew Hall
et al.
DHFR and MSH3 co-amplification in childhood acute lymphoblastic leukaemia, in vitro and in vivo2007
Elizabeth Matheson
Lynne Minto
Professor Anthony Moorman
Dr Andrew Hall
Professor Julie Irving
et al.
Variable Breakpoints Target PAX5 in Patients with Dicentric Chromosomes: A Model for the Basis of Unbalanced Translocations in Cancer2007
Professor Julie Irving
Lynne Minto
Elizabeth Matheson
Dr Lindsay Nicholson
Dr Andrew Hall
et al.
Glucocorticoid resistance in two key models of acute lymphoblastic leukemia occurs at the level of the glucocorticoid receptor2006
Professor Julie Irving
Lynne Minto
Elizabeth Matheson
Marian Case
Professor Simon Bailey
et al.
Mutation in genes impacting on the RAS-RAF-MEK-ERK pathway are found at high incidence in childhood acute lymphoblastic leukemia at both diagnosis and at relapse.2006
Dr Mark Velangi
Elizabeth Matheson
Dr Andrew Hall
Professor Julie Irving
Detecting mismatch repair defects in myeloma2005
Dr Mark Velangi
Elizabeth Matheson
Dr Penelope Taylor
Professor Graham Jackson
Dr Andrew Hall
et al.
BRAF gene is not mutated in mismatch repair-proficient or -deficient plasma cell dyscrasias 2004
Dr Mark Velangi
Elizabeth Matheson
Professor Graham Jackson
Dr Penelope Taylor
Dr Andrew Hall
et al.
DNA mismatch repair pathway defects in the pathogenesis and evolution of myeloma2004
Elizabeth Matheson
Dr Andrew Hall
Assessment of mismatch repair function in leukaemic cell lines and blasts from children with acute lymphoblastic leukaemia2003
Elizabeth Matheson
Dr Andrew Hall
Interactions of the DNA mismatch repair proteins MLH1 and MSH2 with c-MYC and MAX2003
Penelope Mason
Elizabeth Matheson
Dr Andrew Hall
Professor Robert Lightowlers
Mismatch repair activity in mammalian mitochondria2003
Dr Andrew Hall
Elizabeth Matheson
Mismatch repair defects in acute lymphoblastic leukaemia2003
Dr Sally Coulthard
Dr Linda Hogarth
Dr Margaret Little
Elizabeth Matheson
Dr Chris Redfern
et al.
The effect of thiopurine methyltransferase expression on sensitivity to thiopurine drugs2002
Elizabeth Matheson
Dr Andrew Hall
Drug discovery - High throughput automated 2-D gel analysis - Tutorial: Proteomic analysis with nonlinear dynamics' progenesis image analysis software2001
Dr Linda Hogarth
Elizabeth Matheson
Lynne Minto
Dr Margaret Little
Dr Andrew Hall
et al.
Measurement of resistance to thiopurine drugs in cells with defective mismatch repair2000
Dr Michael Reid
Elizabeth Matheson
Dr Penelope Taylor
Professor Stephen Proctor
Dr Andrew Hall
et al.

Corticosteroid resistance is increased in lymphoblasts from adults compared with children: preliminary results of in vitro drug sensitivity study in adults with acute lymphoblastic leukaemia

1995
Dr Andrew Hall
Elizabeth Matheson
Dr Linda Hogarth
Purification of an alpha class glutathione S-transferase from melphalan-resistant Chinese hamster ovary cells and demonstration of its ability to catalyze melphalan-glutathione adduct formation1994