Browsing publications by Dr Xiaohong Lu

Newcastle AuthorsTitleYearFull text
Dr Catherine Drummond
Arman Esfandiari
Dr Xiaohong Lu
Dr Claire Hutton
Dr Jennifer Jackson
et al.
TP53 mutant MDM2-amplified cell lines selected for resistance to MDM2-p53 binding antagonists retain sensitivity to ionizing radiation2016
Dr Andrey Zaytsev
Dr Barry Dodd
Professor Bernard Golding
Professor Roger Griffin
Dr Xiaohong Lu
et al.
Searching for Dual Inhibitors of the MDM2-p53 and MDMX-p53 Protein-Protein Interaction by a Scaffold-Hopping Approach2015
Dr Tim Blackburn
Christopher Coxon
Dr Xiaohong Lu
Professor Bernard Golding
Professor Roger Griffin
et al.
Diaryl- and triaryl-pyrrole derivatives: inhibitors of the MDM2-p53 and MDMX-p53 protein-protein interactions2013
Dr Ian Hardcastle
Alex Liu
Dr Eric Valeur
Anna Watson
Shafiq Ahmed
et al.
Isoindolinone Inhibitors of the Murine Double Minute 2 (MDM2)-p53 Protein-Protein Interaction: Structure-Activity Studies Leading to Improved Potency2011
Dr Ian Logan
Hesta McNeill
Susan Cook
Dr Xiaohong Lu
Professor John Lunec
et al.
Heat shock factor-1 modulates p53 activity in the transcriptional response to DNA damage2009
Dr Xiaohong Lu
Professor John Lunec
Disruption of the MYC transcriptional function by a small-molecule antagonist of MYC/MAX dimerization2008
Dr Ian Logan
Hesta McNeill
Susan Cook
Dr Xiaohong Lu
Professor John Lunec
et al.
Analysis of the MDM2 antagonist nutlin-3 in human prostate cancer cells2007
Dr Emma Bell
Dr Jane Carr-Wilkinson
Dr Xiaohong Lu
Professor Penny Lovat
Professor John Lunec
et al.
The role of MYCN in the failure of MYCN amplified neuroblastoma cell lines to G1 arrest after DNA damage2006
Dr Xiaohong Lu
Professor Herbie Newell
Professor Andrew Pearson
Professor John Lunec
Identification of MYCN transcriptional activity inhibitors yields compounds which preferentially inhibit the growth of neuroblastoma cells2004
Dr Xiaohong Lu
Professor Andrew Pearson
Professor John Lunec
The MYCN oncoprotein as a drug development target2003
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