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Browsing publications by Professor David Lydall.

Newcastle AuthorsTitleYearFull text
Dr Andrew Banks
Professor David Lydall
Checkpoint inhibition of origin firing prevents DNA topological stress2019
Professor David Lydall
Cis and trans interactions between genes encoding PAF1 complex and ESCRT machinery components in yeast2018
Dr Marta Markiewicz-Potoczny
Professor David Lydall
A critical role for Dna2 at unwound telomeres2018
Dr Eva-Maria Holstein
Dr Conor Lawless
Dr Andrew Banks
Professor David Lydall
Genome-wide Quantitative Fitness Analysis (QFA) of yeast cultures2018
Victoria Torrance
Professor David Lydall
Overlapping open reading frames strongly reduce human and yeast STN1 gene expression and affect telomere function2018
Professor David Lydall
Paf1 and Ctr9, core components of the PAF1 complex, maintain low levels of telomeric repeat containing RNA2018
Dr Andrew Banks
Dr Conor Lawless
Professor David Lydall
The contribution of non-essential Schizosaccharomyces pombe genes to fitness in response to altered nutrient supply and target of rapamycin activity2018
Dr Andrew Banks
Professor David Lydall
Vps74 connects the golgi apparatus and telomeres in Saccharomyces cerevisiae2018
Adam Ciesiolka
Dr Conor Lawless
Professor David Lydall
A Functional Link Between Bir1 and the Saccharomyces cerevisiae Ctf19 Kinetochore Complex Revealed Through Quantitative Fitness Analysis2017
Dr Eva-Maria Holstein
Dr Conor Lawless
Dr Andrew Banks
Professor Darren Wilkinson
Professor David Lydall
et al.
Systematic Analysis of the DNA Damage Response Network in Telomere Defective Budding Yeast2017
Jonathan Heydari
Dr Conor Lawless
Professor David Lydall
Professor Darren Wilkinson
Bayesian hierarchical modelling for inferring genetic interactions in yeast2016
Marta Markiewicz-Potoczny
Professor David Lydall
Costs, benefits and redundant mechanisms of adaption to chronic low-dose stress in yeast2016
Melanie Ikeh
Dr Alison Day
Dr Emma Tarrant
Dr Kevin Waldron
Dr Andrew Banks
et al.
Pho4 mediates phosphate acquisition in Candida albicans and is vital for stress resistance and metal homeostasis2016
Yuan Xue
Dr Iglika Ivanova
Professor David Lydall
Dr Laura Maringele
Rif1 and Exo1 regulate the genomic instability following telomere losses2016
Dr Marion Dubarry
Dr Conor Lawless
Dr Andrew Banks
Dr Simon Cockell
Professor David Lydall
et al.
Genetic Networks Required to Coordinate Chromosome Replication by DNA Polymerases α, δ, and ε in Saccharomyces cerevisiae2015
Dr Siddharth Narayanan
Dr Marion Dubarry
Dr Conor Lawless
Dr Andrew Banks
Professor Darren Wilkinson
et al.
Quantitative Fitness Analysis Identifies exo1∆ and Other Suppressors or Enhancers of Telomere Defects in Schizosaccharomyces pombe2015
Dr Greg Ngo
Professor David Lydall
The 9-1-1 checkpoint clamp coordinates resection at DNA double strand breaks2015
Matthew Greetham
Professor David Lydall
Professor Bernard Connolly
The Telomere Binding Protein Cdc13 and the Single-Stranded DNA Binding Protein RPA Protect Telomeric DNA from Resection by Exonucleases2015
Jonathan Heydari
Dr Conor Lawless
Professor David Lydall
Professor Darren Wilkinson
Fast Bayesian parameter estimation for stochastic logistic growth models2014
Dr Eva-Maria Holstein
Kate Clark
Professor David Lydall
Interplay between Nonsense-Mediated mRNA Decay and DNA Damage Response Pathways Reveals that Stn1 and Ten1 Are the Key CST Telomere-Cap Components2014
Dr Greg Ngo
Dr Marion Dubarry
Professor David Lydall
The 9-1-1 checkpoint clamp stimulates DNA resection by Dna2-Sgs1 and Exo12014
Lizzy Andrew
Dr Stephanie Merchan
Dr Conor Lawless
Dr Andrew Banks
Professor Darren Wilkinson
et al.
Pentose Phosphate Pathway Function Affects Tolerance to the G-Quadruplex Binder TMPyP42013
Kangzhen Dong
Dr Stephen Addinall
Professor David Lydall
Dr Julian Rutherford
The Yeast Copper Response Is Regulated by DNA Damage2013
Dr Andrew Banks
Dr Conor Lawless
Professor David Lydall
A Quantitative Fitness Analysis Workflow2012
James Dewar
Professor David Lydall
Similarities and differences between "uncapped" telomeres and DNA double-strand breaks2012
Jochen Weile
Dr Matthew Pocock
Dr Simon Cockell
Dr Phillip Lord
James Dewar
et al.
Customizable views on semantically integrated networks for systems biology2011
Dr Hsin Yu Chang
Dr Conor Lawless
Dr Stephen Addinall
Morgan Taschuk
Professor Anil Wipat
et al.
Genome-Wide Analysis to Identify Pathways Affecting Telomere-Initiated Senescence in Budding Yeast2011
Dr Stephen Addinall
Dr Eva-Maria Holstein
Dr Conor Lawless
Dr Min Yu
Dr Kaye Chapman
et al.
Quantitative Fitness Analysis Shows That NMD Proteins and Many Other Protein Complexes Suppress or Enhance Distinct Telomere Cap Defects2011
Dr Conor Lawless
Professor Darren Wilkinson
Dr Stephen Addinall
Professor David Lydall
Colonyzer: automated quantification of micro-organism growth characteristics on solid agar2010
James Dewar
Professor David Lydall
Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping2010
Dr Greg Ngo
Professor David Lydall
Survival and Growth of Yeast without Telomere Capping by Cdc13 in the Absence of Sgs1, Exo1, and Rad92010
James Dewar
Professor David Lydall
Telomere Replication: Mre11 Leads the Way2010
Dr Jennifer Hallinan
Dr Matthew Pocock
Dr Stephen Addinall
Professor David Lydall
Professor Anil Wipat
et al.
Clustering incorporating shortest paths identifies relevant modules in functional interaction networks2009
Professor David Lydall
Taming the tiger by the tail: modulation of DNA damage responses by telomeres2009
Professor David Lydall
Dr Laura Maringele
Telomere Maintenance and Survival in Saccharomyces cerevisiae in the Absence of Telomerase and RAD522009
Dr Amanda Greenall
Dr Daniel Swan
Dr Heiko Peters
Professor Anil Wipat
Professor Darren Wilkinson
et al.
A genome wide analysis of the response to uncapped telomeres in budding yeast reveals a novel role for the NAD(+) biosynthetic gene BNA2 in chromosome end protection2008
Dr Stephen Addinall
Dawn Downey
Dr Min Yu
Dr Mikhajlo Zubko
James Dewar
et al.
A Genome-wide Suppressor and Enhancer Analysis of cdc13-1 Reveals Varied Cellular Processes Influencing Telomere Capping in Saccharomyces cerevisiae2008
Dr Isabelle Morin
Dr Greg Ngo
Dr Amanda Greenall
Dr Mikhajlo Zubko
Professor David Lydall
et al.
Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response2008
Dr Vasileia Sapountzi
Professor David Lydall
Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres2008
Dr Vasileia Sapountzi
Dr Amanda Greenall
Professor David Lydall
The SAS2 histone acetyltransferase is important for the telomere uncapping response2008
Dr Carole Proctor
Professor David Lydall
Professor Richard Boys
Dr Colin Gillespie
Dr Daryl Shanley
et al.
Modelling the checkpoint response to telomere uncapping in budding yeast2007
Professor David Lydall
Mrc1 protects uncapped budding yeast telomeres from exonuclease EXO12007
Dr Laura Maringele
Dr Mikhajlo Zubko
Professor David Lydall
A Genome-Wide Screen Identifies the Evolutionarily Conserved KEOPS Complex as a Telomere Regulator2006
Dr Mikhajlo Zubko
Dr Laura Maringele
Steven Foster
Professor David Lydall
Detecting repair intermediates in vivo: Effects of DNA damage response genes on single-stranded DNA accumulation at uncapped telomeres in budding yeast2006
Dr Mikhajlo Zubko
Professor David Lydall
Linear chromosome maintenance in the absence of essential telomere-capping proteins2006
Steven Foster
Dr Mikhajlo Zubko
Professor David Lydall
MRX protects telomeric DNA at uncapped telomeres of budding yeast cdc13-1 mutants2006
Professor David Lydall
Dr Simon Whitehall
Chromatin and the DNA damage response2005
Dr Laura Maringele
Professor David Lydall
Pulsed Field Gel Electrophoresis of Budding Yeast Chromosomes2005
Dr Laura Maringele
Professor David Lydall
The PAL-mechanism of Chromosome Maintenance: Causes and Consequences2005
Professor David Lydall
A domain of Rad9 specifically required for activation of Chk1 in budding yeast2004
Professor David Lydall
Exo1 and Rad24 differentially regulate generation of ssDNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants2004
Dr Laura Maringele
Professor David Lydall
EXO1 Plays a Role in Generating Type I and Type II Survivors in Budding Yeast2004
Professor David Lydall
Mec1 and Rad53 Inhibit Formation of Single-Stranded DNA at Telomeres of Saccharomyces cerevisiae cdc13-1 Mutants2004
Dr Laura Maringele
Professor David Lydall
Telomerase- and recombination-independent immortalization of budding yeast2004
Professor David Lydall
Hiding at the ends of yeast chromosomes: telomeres, nucleases and checkpoint pathways2003
Dr Laura Maringele
Professor David Lydall
EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Δ mutants2002
Chloe Booth
Professor David Lydall
Quantitative amplification of single-stranded DNA (QAOS) demonstrates that cdc13-1 mutants generate ssDNA in a telomere to centromere direction2001
Professor David Lydall
Checkpoint proteins and the metabolism of DNA damage2000
Professor David Lydall
NDD1, a high-dosage suppressor of cdc28-1N, is essential for expression of a subset of late-S-phase-specific genes in Saccharomyces cerevisiae1999