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Browsing publications by Dr Anja Krippner-Heidenreich.

Newcastle AuthorsTitleYearFull text
Dr Anja Krippner-Heidenreich
TNF-α–induced protein 3 (TNFAIP3)/A20 acts as a master switch in TNF-α blockade–driven IL-17A expression2018
Zakareya Gamie
Dr Emma Haagensen
Ricardo da Conceicao Ribeiro
Professor Kenneth Dalgarno
Dr Anja Krippner-Heidenreich
et al.
TNF-related apoptosis-inducing ligand (TRAIL) for bone sarcoma treatment: Pre-clinical and clinical data2017
Marilena Patsalidou
Dr Amy Anderson
Dr Anja Krippner-Heidenreich
An unconventional anti-inflammatory role for TNF recpetor (TNFR)1 in tregs: TNFR1 and 2 differetnialy modulate FOXP3+ TREG function2014
Dr Nicola Maney
Dr Gary Reynolds
Dr Anja Krippner-Heidenreich
Professor Catharien Hilkens
Dendritic Cell Maturation and Survival Are Differentially Regulated by TNFR1 and TNFR22014
Professor Jaap van Laar
Dr Anja Krippner-Heidenreich
CLL cells are resistant to smac mimetics because of an inability to form a ripoptosome complex2013
Dr Thomas Huegle
Dr Steven O'Reilly
Rachel Simpson
Dr Venetia Bigley
Professor Matthew Collin
et al.
Tumor Necrosis Factor-Costimulated T Lymphocytes From Patients With Systemic Sclerosis Trigger Collagen Production in Fibroblasts2013
Dr Steven O'Reilly
Dr Bridget Griffiths
Dr Anja Krippner-Heidenreich
Professor Jaap Van Laar
T cell derived IL-6 and IL-13 drive fibroblast fibrosis: Implications for systemic sclerosis2012
Dr Aaron Ions Gardner
Professor Andrew Fisher
Christine Richter
Grace Johnson
Dr Elizabeth Moisey
et al.
The Critical Role of TAK1 in Accentuated Epithelial to Mesenchymal Transition in Obliterative Bronchiolitis after Lung Transplantation2012
Simon Neumann
Dr Anja Krippner-Heidenreich
The Transmembrane Domains of TNF-Related Apoptosis-Inducing Ligand (TRAIL) Receptors 1 and 2 Co-Regulate Apoptotic Signaling Capacity2012
Christine Richter
Professor Derek Mann
Dr Anja Krippner-Heidenreich
The Tumor Necrosis Factor Receptor Stalk Regions Define Responsiveness to Soluble versus Membrane-Bound Ligand2012
Dr Steven O'Reilly
Dr Venetia Bigley
Professor Matthew Collin
Dr Anja Krippner-Heidenreich
Professor Jaap van Laar
et al.
Tumor necrosis factor-alpha co-activated T-cells support a profibrotic cytokine milieu on cost of IL-10 expression in patients with systemic sclerosis2012
Dr Anja Krippner-Heidenreich
Analysis of ligand receptor interaction with new single chain TNF derivatives2011
Dr Anja Krippner-Heidenreich
Ligand-induced internalization of TNF receptor 2 mediated by a di-leucin motif is dispensable for activation of the NFκB pathway2011
Dr Steven O'Reilly
Dr Thomas Huegle
Dr Anja Krippner-Heidenreich
Professor Jaap Van Laar
T cell-derived IL-6 and IL-13 drive dermal fibrosis: implications for systemic sclerosis2011
Dr Anja Krippner-Heidenreich
The stalk region of the TNF receptors highly determines soluble TNF responsiveness2011
Dr Thomas Huegle
Dr Anja Krippner-Heidenreich
Rachel Simpson
Dr Steven O'Reilly
Dr Venetia Bigley
et al.
Tumour necrosis factor alpha receptor activated T cells of patients with systemic sclerosis are deficient in IL-10 expression but promote myofibroblast differentiation via IL-6 and TGF-beta2011
Dr Anja Krippner-Heidenreich
Dual function of cysteine rich domain (CRD) 1 of TNF receptor type 1: conformational stabilization of CRD2 and control of receptor responsiveness2010
Dr Anja Krippner-Heidenreich
Fluorescence correlation spectroscopy reveals topological segregation of the two tumor necrosis factor membrane receptors2010
Dr Anja Krippner-Heidenreich
Potent antitumoral activity of TRAIL through generation of tumor-targeted single-chain fusion proteins2010
Dr Nicola Maney
Helen Baldwin
Dr Anja Krippner-Heidenreich
Professor Catharien Hilkens
Regulation of dendritic cell survival and function by tumour necrosis factor receptors 1 and 22010
Dr Anja Krippner-Heidenreich
Single chain TNF derivatives with individually mutated receptor binding sites reveal differential stoichiometry of ligand receptor complex formation for TNFR1 and TNFR22010
Dr Anja Krippner-Heidenreich
Nanoscale Arrangement of Apoptotic Ligands Reveals a Demand for a Minimal Lateral Distance for Efficient Death Receptor Activation2009
Dr Anja Krippner-Heidenreich
Dr Jason Gill
Single-Chain TNF, a TNF Derivative with Enhanced Stability and Antitumoral Activity2008
Dr Anja Krippner-Heidenreich
Tumour necrosis factors (review)2007
Dr Anja Krippner-Heidenreich
Caspase-dependent cleavage and subcellular redistribution of YY1 during apoptosis enhances proapoptotitic activity2005
Dr Anja Krippner-Heidenreich
The Met196Arg variation of human TNFR2 affects TNF-induced apoptosis by impaired NF-B-signalling and target gene expression2005
Dr Anja Krippner-Heidenreich
TNF-Funtionalized nanostructured particles for the stimulation of Membrane TNF-specific Cell responses2005
Dr Anja Krippner-Heidenreich
[reviwe] FasL and Fas: typical members of the TNF ligand and receptor family2004
Dr Anja Krippner-Heidenreich
Control of receptor-induced signaling complex formation by the kinetics of ligand/receptor interaction2002
Dr Anja Krippner-Heidenreich
Targeting of the transcription factor Max during apoptosis: phosphorylation-regulated cleavage by caspase-5 at an unusual glutamic acid residue in position P12001
Dr Anja Krippner-Heidenreich
Inhibition of proliferation and apoptosis by the transcriptional repressor Mad1: Repression of Fas-induced caspase-8 activation2000