About Open Access
Epidemiology of bone tumours in children and young adults
Lookup NU author(s)
Dr Richard McNally
Eyre R, Feltbower RG, Mubwandarikwa E, Eden TO, McNally RJ
Pediatric Blood and Cancer
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
Although the epidemiology of malignant bone tumours in children and young adults has been explored, no definitive causation of any specific tumour has yet been identified. We performed a literature review (1970 – 2008) to find all papers covering possible aetiological factors involved in the development of bone tumours in children and young adults. Several associations have been reported with some consistency: the presence of hernias and Ewing sarcoma; high fluoride exposure and osteosarcoma; and parental farming and residence on a farm, younger age at puberty and family history of cancer for all bone tumours, especially osteosarcoma. Clearly further research is needed to confirm or refute these putative risk factors. It is likely that studies of gene-environment interactions may prove to be the most fruitful of future research.
John Wiley & Sons, Inc.
Altmetrics provided by
Newcastle University Library, NE2 4HQ, United Kingdom. Tel: 0044 (191) 208 2920
©2018 Newcastle University Library