Complete Mitochondrial Genome Sequence of the Tyrolean Iceman

  1. Lookup NU author(s)
  2. Dr Luca Ermini
Author(s)Ermini L, Olivieri C, Rizzi E, Corti G, Bonnal R, Soares P, Luciani S, Marota I, De Bellis G, Richards MB, Rollo F
Publication type Article
JournalCurrent Biology
Year2008
Volume18
Issue21
Pages1687-1693
ISSN (print)0960-9822
ISSN (electronic)1879-0445
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
The Tyrolean Iceman was a witness to the Neolithic-Copper Age transition in Central Europe 5350-5100 years ago, and his mummified corpse was recovered from an Alpine glacier on the Austro-Italian border in 1991 [1]. Using a mixed sequencing procedure based on PCR amplification and 454 sequencing of pooled amplification products, we have retrieved the first complete mitochondrial-genome sequence of a prehistoric European. We have then compared it with 115 related extant lineages from mitochondrial haplogroup K. We found that the Iceman belonged to a branch of mitochondrial haplogroup K1 that has not yet been identified in modern European populations. This is the oldest complete Homo sapiens mtDNA genome generated to date. The results point to the potential significance of complete-ancient-mtDNA studies in addressing questions concerning the genetic history of human populations that the phylogeography of modern lineages is unable to tackle.
PublisherCell Press
URLhttp://dx.doi.org/10.1016/j.cub.2008.09.028
DOI10.1016/j.cub.2008.09.028
Actions    Link to this publication
Share