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A Grid-based System for Microbial Genome Comparison and Analysis
Lookup NU author(s)
Dr Yudong Sun
Professor Anil Wipat
Dr Matthew Pocock
Professor Pete Lee
Professor Paul Watson
Dr Keith Flanagan
James Worthington
Author(s)
Sun Y, Wipat A, Pocock M, Lee P, Watson P, Flanagan K, Worthington J
Publication type
Report
Series Title
School of Computing Science Technical Report Series
Year
2004
Date
December 2004
Report Number
881
Pages
8
Full text is available for this publication:
Full text file 1
Genome comparison and analysis can reveal the structures and functions of genome sequences of different species. As more genomes are sequenced, genomic data sources are increasing in size and availability such that their analysis is beyond the processing capabilities of most research institutes. The Grid is a powerful solution to support large-scale genomic data processing and genome analysis. This paper presents the Microbase project that is developing a Grid-based system for genome comparison and analysis, and discusses the first implementation of the system (called MicrobaseLite). MicrobaseLite uses a scalable computing environment to support computationally intensive microbial genome comparison and analysis, employing state-of-the-art technologies of Web Services, notification, comparative genomics and parallel computing. Microbase will support not only system-defined genome comparison and analysis but also user-defined, remotely conceived genome analysis.
Institution
School of Computing Science, University of Newcastle upon Tyne
Place Published
Newcastle upon Tyne
URL
http://www.cs.ncl.ac.uk/publications/inproceedings/papers/850.pdf
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