Browse by author
Lookup NU author(s): Emerita Professor Helen Foster
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
Objectives Adolescents with juvenile idiopathic arthritis have demonstrated substantial disagreement with their proxy's assessment of their disability, pain, and well-being. Our objective was to describe the clinical and psychological factors associated with discordance. Study design This analysis included 204 proxy-adolescent (median age, 13 years) dyads that completed a Childhood Health Assessment Questionnaire for disability with 100-mm visual analogue scales for pain and well-being. Depressive symptoms in adolescents were measured by the Mood and Feelings Questionnaire and in proxies the General Health Questionnaire. Disagreement was assessed using Bland-Altman plots. Associations with discordance were identified using logistic regression analyses. Results There was higher agreement for disability (84%) than for pain (71%) and well-being (66%). Regression analyses found no association between age, sex, or disease duration and disagreement. However, relationships between disease activity and disagreement in outcomes were identified. Independent associations were found between increasing Mood and Feelings Questionnaire scores and disagreement in pain and well-being. Conclusions Proxy and adolescent reports of pain and well-being are more likely to disagree in those with severe disease. Adolescents who report depressive symptoms are also more likely to disagree with their proxy. The reasons for these are multifactorial, and considerations of both reports are important when assessing outcomes in juvenile idiopathic arthritis. (J Pediatr 2011; 158:307-12).
Author(s): Lal SD, McDonagh J, Baildam E, Wedderburn LR, Gardner-Medwin J, Foster HE, Chieng A, Davidson J, Adib N, Thomson W, Hyrich KL
Publication type: Article
Publication status: Published
Journal: Journal of Pediatrics
Year: 2011
Volume: 158
Issue: 2
Pages: 307-312
Print publication date: 01/02/2011
ISSN (print): 0022-3476
ISSN (electronic): 1097-6833
Publisher: Mosby, Inc.
URL: http://dx.doi.org/10.1016/j.jpeds.2010.08.003
DOI: 10.1016/j.jpeds.2010.08.003
Altmetrics provided by Altmetric
