Cellular mechanisms of high frequency oscillations in epilepsy: on the diverse sources of pathological activities
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- Dr Andrew Trevelyan
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| Author(s) | | Prida L, Trevelyan AJ |
| Publication type | | Review |
| Journal | | Epilepsy Research |
| Year | | 2011 |
| Volume | | 97 |
| Issue | | 3 |
| Pages | | 308-317 |
| ISSN (print) | | 0920-1211 |
| ISSN (electronic) | | 1872-6844 |
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| Full text for this publication is not currently held within this repository. Alternative links are provided below where available. |
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| A major goal in epilepsy research is to understand the cellular basis of pathological forms of network oscillations, particularly those classified as high-frequency activity. What are the underlying mechanisms, and how do they arise? The topic of this review is the pattern of high-frequency oscillations that have been recorded in epileptic tissue, and how they might differ from physiological activity. We discuss recent experimental and clinical data with a major focus on the diverse sources of extracellular signals and the contribution of different neuronal populations, including GABAergic interneurons and glutamatergic principal cells. |
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| URL | | http://dx.doi.org/10.1016/j.eplepsyres.2011.02.009 |
| DOI | | 10.1016/j.eplepsyres.2011.02.009 |
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