Cellular mechanisms of high frequency oscillations in epilepsy: on the diverse sources of pathological activities

  1. Lookup NU author(s)
  2. Dr Andrew Trevelyan
Author(s)Prida L, Trevelyan AJ
Publication type Review
JournalEpilepsy Research
Year2011
Volume97
Issue3
Pages308-317
ISSN (print)0920-1211
ISSN (electronic)1872-6844
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
A major goal in epilepsy research is to understand the cellular basis of pathological forms of network oscillations, particularly those classified as high-frequency activity. What are the underlying mechanisms, and how do they arise? The topic of this review is the pattern of high-frequency oscillations that have been recorded in epileptic tissue, and how they might differ from physiological activity. We discuss recent experimental and clinical data with a major focus on the diverse sources of extracellular signals and the contribution of different neuronal populations, including GABAergic interneurons and glutamatergic principal cells.
URLhttp://dx.doi.org/10.1016/j.eplepsyres.2011.02.009
DOI10.1016/j.eplepsyres.2011.02.009
Actions    Link to this publication
Share