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Cell division blockage: but this time by a surprisingly conserved protein

Lookup NU author(s): Dr Leendert Hamoen

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Abstract

Activation of DNA repair proteins is often accompanied by an arrest in cell division. Several proteins have been identified that regulate the division blockage associated with the SOS response. When Bacillus subtilis cells become genetically competent they also activate DNA repair proteins and stop dividing. In this issue of Molecular Microbiology, Briley et al., 2011 describe a new protein involved in this process. This protein, Maf, does not prevent FtsZ polymerization, but it inhibits synthesis of the division septum. What is fascinating about Maf is that it is conserved and can be found in all kingdoms of life.

Publication metadata

Author(s): Hamoen LW

Publication type: Editorial

Publication status: Published

Journal: Molecular Microbiology

Year: 2011

Volume: 81

Issue: 1

Pages: 1-3

Print publication date: 19/05/2011

ISSN (print): 0950-382X

ISSN (electronic): 1365-2958

Publisher: Wiley-Blackwell Publishing Ltd.

URL: http://dx.doi.org/10.1111/j.1365-2958.2011.07693.x

DOI: 10.1111/j.1365-2958.2011.07693.x

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