Inflammatory myofibroblastic tumours of the respiratory tract: paediatric case series with varying clinical presentations

  1. Lookup NU author(s)
  2. Dr Malcolm Brodlie
  3. Dr Michael McKean
  4. Andrew Welch
Author(s)Brodlie M, Barwick SC, Wood KM, McKean MC, Welch A
Publication type Article
JournalJournal of Laryngology and Otology
ISSN (print)0022-2151
ISSN (electronic)1748-5460
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Objectives: To highlight the clinical importance of inflammatory myofibroblastic tumours of the respiratory tract in children, and to present a case series of three children which illustrates this tumour's variable clinical presentation.Case history: The series includes: a nine-year-old girl with a diagnosis of juvenile idiopathic arthritis, who presented with finger clubbing and was found to have an inflammatory myofibroblastic tumour in her right upper lobe; a 15-year-old adolescent with a left main stem bronchial inflammatory myofibroblastic tumour, who presented with breathlessness and chest pain; and a 12-year-old girl with a tracheal inflammatory myofibroblastic tumour who presented with stridor. In each case, the tumour was resected surgically.Conclusion: Inflammatory myofibroblastic tumour are a rare but clinically important and pathologically distinct lesion of the respiratory tract in children. The cases in this series highlight some of the varied clinical presentations of inflammatory myofibroblastic tumours, and illustrate some of this tumour's different anatomical locations within the paediatric respiratory tract.
PublisherCambridge University Press
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