Asymmetric carbonyl-Ene and Friedel-Crafts reactions catalyzed by Lewis acid platinum group metal complexes of the enantiopure atropisomeric biaryl-like diphosphine (S)-Me2-CATPHOS: a comparison with BINAP
- Lookup NU author(s)
- Dr Simon Doherty
- Dr Julian Knight
- Hamid Mehdi-Zodeh
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| Author(s) | | Doherty S, Knight JG, Mehdi-Zodeh H |
| Publication type | | Article |
| Journal | | Tetrahedron: Asymmetry |
| Year | | 2012 |
| Volume | | 23 |
| Issue | | 3-4 |
| Pages | | 209-216 |
| ISSN (print) | | 0957-4166 |
| ISSN (electronic) | | 1362-511X |
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| Full text for this publication is not currently held within this repository. Alternative links are provided below where available. |
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| Lewis acid platinum and palladium complexes of (S)-Me2-CATPHOS catalyze the carbonyl-ene reaction between allylbenzene derivatives and ethyl trifluoropyruvate to give the expected a-hydroxy esters with ee’s up to 97% while the corresponding reaction involving 2-allylfuran and thiophene were exclusively selective for Friedel-Crafts-type reactivity and gave the corresponding 2-hydroxy-trifluoromethyl ethyl esters in good yield and moderate to good enantioselectivity. |
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| Publisher | | Pergamon |
| URL | | http://dx.doi.org/10.1016/j.tetasy.2012.01.022 |
| DOI | | 10.1016/j.tetasy.2012.01.022 |
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