Diastereoselective intermolecular ene reactions: synthesis of 4,5,6,7-tetrahydro-1H-benzo[d]imidazoles
- Lookup NU author(s)
- Dr Ross Harrington
- Emeritus Professor William Clegg
- Dr Michael Hall
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| Author(s) | | Watson LJ, Harrington RW, Clegg W, Hall MJ |
| Publication type | | Article |
| Journal | | Organic and Biomolecular Chemistry |
| Year | | 2012 |
| Volume | | 10 |
| Issue | | 33 |
| Pages | | 6649-6655 |
| ISSN (print) | | 1477-0520 |
| ISSN (electronic) | | 1477-0539 |
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| Full text for this publication is not currently held within this repository. Alternative links are provided below where available. |
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| The Diels-Alder cycloadducts of 4-vinylimidazoles and N-phenylmaleimide are shown to undergo facile intermolecular ene reactions. Overall the reaction of three simple molecules (a diene, a dienophile and an enophile) in a two-step process gives 4,5,6,7-tetrahydro-1H-benzo[d]imidazoles with high yields, high atom economy and diastereocontrol of up to 5 new stereocentres. |
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| Publisher | | Royal Society of Chemistry |
| URL | | http://dx.doi.org/10.1039/C2OB26009C |
| DOI | | 10.1039/C2OB26009C |
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