Cognitive function after two doses of cranial irradiation for acute lymphoblastic leukaemia.

  1. Lookup NU author(s)
  2. Dr Jacqueline Rodgers
  3. Professor Peter Britton
  4. Dr Jennifer Kernahan
  5. Emeritus Professor Sir Craft
Author(s)Rodgers J, Britton PG, Kernahan J, Craft AW
Publication type Article
JournalArch Dis Child
ISSN (print)0003-9888
ISSN (electronic)1468-2044
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The cognitive function of 23 children given cranial irradiation in a dose of 24 Gy was compared with that of 41 given 18 Gy. No significant differences were found in intellectual function or in mean number of intelligence quotient points lost between patients in the two treatment groups. A reduction in the dose of cranial irradiation does not seem to alleviate long term neuropsychological deficits.
PubMed id1953013
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