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Molecular Cross-Talk at the Feto-Maternal Interface

Lookup NU author(s): Dr Gendie Lash

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Abstract

Molecular cross-talk at the feto-maternal interface occurs between many different cell types, including uterine leukocytes, extravillous trophoblast cells, and uterine spiral arteries, is essential for the establishment and maintenance of pregnancy. This review concentrates on human pregnancy and examines three main areas in which cross-talk occurs; immune tolerance, regulation of extravillous trophoblast invasion, and remodeling of the uterine spiral arteries.

Publication metadata

Author(s): Lash GE

Publication type: Article

Publication status: Published

Journal: Cold Spring Harbor Perspectives in Medicine

Year: 2015

Volume: 5

Issue: 12

Pages: 1-15

Print publication date: 01/12/2015

Online publication date: 18/09/2015

Acceptance date: 01/01/1900

ISSN (electronic): 2157-1422

Publisher: Cold Spring Harbor Laboratory Press

URL: http://dx.doi.org/10.1101/cshperspect.a023010

DOI: 10.1101/cshperspect.a023010

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