About Open Access
Paranoid Psychosis and Myoclonus: Flecainide Toxicity in Renal Failure
Lookup NU author(s)
Dr Daniela Lee
Professor Neil Sheerin
Ting SM, Lee D, Maclean D, Sheerin NS
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
Flecainide is a sodium channel blocker used mainly in the treatment of supraventricular arrhythmias. Central nervous system side effects such as dizziness, visual disturbances, headache and nausea are commonly associated with flecainide, but severe central nervous system toxicity is rare. We report the first case of flecainide toxicity in a patient with end-stage renal failure. Cessation of flecainide therapy resulted in a fall in serum flecainide levels, with associated resolution of adverse central nervous system effects. We also review the pharmacokinetics of flecainide in patients with chronic kidney disease. Copyright (c) 2008 S. Karger AG, Basel.
S. Karger AG
Newcastle University Library, NE2 4HQ, United Kingdom. Tel: 0044 (191) 222 7657
©2015 Newcastle University Library