An investigation into the formation of N- [2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and 6-[2-(dimethylamino)ethylamino]- 3-hydroxy-7H-indeno[2,1-C]quinolin-7-one dihydrochloride (TAS-103) stabilised DNA topoisomerase I and II cleavable complexes in human leukaemia cells

Dr Kay Padget; Dr Michael Tilby; Professor Caroline Austin

An investigation into the formation of N- [2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and 6-[2-(dimethylamino)ethylamino]- 3-hydroxy-7H-indeno[2,1-C]quinolin-7-one dihydrochloride (TAS-103) stabilised DNA topoisomerase I and II cleavable complexes in human leukaemia cells Lookup NU author(s) Dr Kay Padget Dr Michael Tilby Professor Caroline Austin



Author(s)		Padget, K., Stewart, A., Charlton, P., Tilby, M.J., Austin, C.A.
Publication type		Article
Journal		Biochemical Pharmacology
Year		2000
Volume		60
Issue		6
Pages		817-821
ISSN (print)		0006-2952
ISSN (electronic)		1873-2968



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URL		http://dx.doi.org/10.1016/S0006-2952(00)00402-0
DOI		10.1016/S0006-2952(00)00402-0
PubMed id		10930536

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