Resistance-modifying agents. 8. Inhibition of O6-alkylguanine-DNA alkyltransferase by O6-alkenyl-, O6-cycloalkenyl-, and O6-(2-oxoalkyl)guanines and potentiation of temozolomide cytotoxicity in vitro by O6-(1-cyclopentenylmethyl) guanine

Professor Roger Griffin; Dr Christine Arris; Dr Christine Bleasdale; Professor Alan Calvert; Professor Nicola Curtin; Professor Herbie Newell; Professor Bernard Golding

Resistance-modifying agents. 8. Inhibition of O⁶-alkylguanine-DNA alkyltransferase by O⁶-alkenyl-, O⁶-cycloalkenyl-, and O⁶-(2-oxoalkyl)guanines and potentiation of temozolomide cytotoxicity in vitro by O⁶-(1-cyclopentenylmethyl) guanine Lookup NU author(s) Professor Roger Griffin Dr Christine Arris Dr Christine Bleasdale Professor Alan Calvert Professor Nicola Curtin Professor Herbie Newell Professor Bernard Golding



Author(s)		Griffin, R. J., Arris, C. E., Bleasdale, C. , Boyle, F., Calvert, A. H., Curtin, N. J., Dalby, C., Kanugula, S., Lembicz, N., Newell, D. R., Pegg, A., Golding, B. T.
Publication type		Article
Journal		Journal of Medicinal Chemistry
Year		2000
Volume		43
Issue		22
Pages		4071-4083
ISSN (print)		0022-2623
ISSN (electronic)		1520-4804



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URL		http://dx.doi.org/10.1021/jm000961o
DOI		10.1021/jm000961o
PubMed id		11063604

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