Temozolomide pharmacodynamics in patients with metastatic melanoma: DNA damage and activity of repair enzymes <em>O</em><sup>6</sup>-alkylguanine alkyltransferase and poly(ADP-ribose) polymerase-1

Temozolomide pharmacodynamics in patients with metastatic melanoma: DNA damage and activity of repair enzymes O⁶-alkylguanine alkyltransferase and poly(ADP-ribose) polymerase-1 Lookup NU author(s) Professor Ruth Plummer Dr Christopher Jones Professor Alan Boddy Professor Alan Calvert Professor Herbie Newell Professor Nicola Curtin



Author(s)		Plummer ER, Middleton MR, Jones C, Olsen A, Hickson I, McHugh P, Margison GP, McGown G, Thorncroft M, Watson AJ, Boddy AV, Calvert AH, Harris AL, Newell DR, Curtin NJ
Publication type		Article
Journal		Clinical Cancer Research
Year		2005
Volume		11
Issue		9
Pages		3402-3409
ISSN (print)		1078-0432
ISSN (electronic)		1557-3265



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URL		http://dx.doi.org/10.1158/1078-0432.CCR-04-2353
DOI		10.1158/1078-0432.CCR-04-2353
PubMed id		15867241

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Temozolomide pharmacodynamics in patients with metastatic melanoma: DNA damage and activity of repair enzymes O6-alkylguanine alkyltransferase and poly(ADP-ribose) polymerase-1