Pyranone, thiopyranone, and pyridone inhibitors of phosphatidylinositol 3-kinase related kinases. Structure-activity relationships for DNA-dependent protein kinase inhibition, and identification of the first potent and selective inhibitor of the ataxia telangiectasia mutated kinase

  1. Lookup NU author(s)
  2. Jonathan Hollick
  3. Dr Laurent Rigoreau
  4. Dr Celine Cano
  5. Professor Nicola Curtin
  6. Professor Bernard Golding
  7. Sophie Guiard
  8. Dr Ian Hardcastle
  9. Professor Herbie Newell
  10. Professor Roger Griffin
Author(s)Hollick J, Rigoreau L, Cano-Soumillac C, Cockcroft X, Curtin NJ, Frigerio M, Golding BT, Guiard S, Hardcastle IR, Hickson I, Hummersone M, Menear K, Martin N, Matthews I, Newell DR, Ord R, Richardson C, Smith G, Griffin RJ
Publication type Article
JournalJournal of Medicinal Chemistry
Year2007
Volume50
Issue8
Pages1958-1972
ISSN (print)0022-2623
ISSN (electronic)1520-4804
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URLhttp://dx.doi.org/10.1021/jm061121y
DOI10.1021/jm061121y
PubMed id17371003
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