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Lookup NU author(s): Dr Jyotsna Shrimankar, Dr Marie Staunton, Clive Griffith
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Aim: To determine the incidence of pre-malignant and malignant conditions in radial scars identified from screening mammograms in women taking part in the UK NHS breast cancer screening programme. Methods: All women in our screening population from 1988 to 2002 with a radiological diagnosis of radial scar or complex sclerosing lesion confirmed on subsequent histopathology were included in this study. Patients were investigated with fine needle aspiration cytology then localisation biopsy (n=46) or straight to localisation biopsy (n = 78). Patients where divided into two groups, one with pure RS/CSL with no associated epithelial features and the second with associated ADH, DCIS or invasive cancer. Results: One hundred and twenty-four lesions were confirmed histologically as radial scar or complex sclerosing lesions. The median age was 58 years. Of the 124 patients, 82 were pure RS/CSL. Forty-two had associated epithelial. lesions, 22 patients had ADH and 20 patients had either in situ or invasive carcinoma. Where FNA was performed (n=46), mammograms had shown three Lesions suspicious of cancer, which were not proven histologically. Mammograms picked up five malignancies out of the nine RS/CSL with associated cancers. Of these, FNA confirmed malignancy in only two patients. Where FNA was not done (n=78), mammogram had read five pure RS/CSL as cancers. It picked up only four cancers in RS lesions with DCIS/Ca out of 11. Conclusion: All screen-detected stellate lesions should be excised due to their association with pre-malignant and malignant conditions. (C) 2005 Elsevier Ltd. All rights reserved.
Author(s): Fasih T, Jain M, Shrimankar J, Staunton M, Hubbard J, Griffith CDM
Publication type: Article
Publication status: Published
Journal: European Journal of Surgical Oncology
Year: 2005
Volume: 31
Issue: 10
Pages: 1125-1128
ISSN (print): 0748-7983
ISSN (electronic): 1532-2157
Publisher: W.B. Saunders Co. Ltd.
URL: http://dx.doi.org/10.1016/j.ejso.2005.04.004
DOI: 10.1016/j.ejso.2005.04.004
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