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Solid alveolar rhabdomyosarcoma with a t(2;13)

Lookup NU author(s): Dr Nicholas Bown, Professor Archibald Malcolm, Dr Michael Reid, Professor Andrew Pearson

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Abstract

We report a child with a progressive ''solid alveolar rhabdomyosarcoma'' in whom analysis of tumor cells revealed a t(2;13) translocation characteristic of the classical alveolar subtype. Both subtypes of alveolar rhabdomyosarcoma are associated with a poor response to treatment and the occurrence of this translocation in both is suggestive of a common biologic origin.

Publication metadata

Author(s): Yule SM, Bown NP, Malcolm AJ, Reid MM, Pearson ADJ

Publication type: Article

Publication status: Published

Journal: Cancer Genetics and Cytogenetics

Year: 1995

Volume: 80

Issue: 2

Pages: 107-109

Print publication date: 01/04/1995

ISSN (print): 0165-4608

ISSN (electronic): 1873-4456

URL: http://dx.doi.org/10.1016/0165-4608(94)00170-G

DOI: 10.1016/0165-4608(94)00170-G

PubMed id: 7736424

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