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Biologically relevant small radicals

Lookup NU author(s): Emeritus Professor Bernard Golding

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Abstract

Biologically relevant small radicals are at the focus of the working group 4 (WG4) of the COST Action CM0603 (Free Radicals in Chemical Biology, CHEMBIORADICAL). This article surveys the areas of research being undertaken by the partners in WG4. The character of the radicals is described together with experimental techniques utilized to follow their structure and reactivity. Specifically, C-, S-, N- and O-centered radicals of small size, and their interaction with different biomolecules are described. Processes at the molecular level exemplifying important biological signaling and damaging pathways are introduced.

Publication metadata

Author(s): Bauer G, Chatgilialoglu C, Gebicki JL, Gebicka L, Gescheidt G, Golding BT, Goldstein S, Kaizer J, Merenyi G, Speier G, Wardman P

Publication type: Article

Publication status: Published

Journal: Chimia

Year: 2008

Volume: 62

Issue: 9

Pages: 704-712

Print publication date: 08/09/2008

ISSN (print): 0009-4293

ISSN (electronic):

Publisher: Swiss Chemical Society

URL: http://dx.doi.org/10.2533/chimia.2008.704

DOI: 10.2533/chimia.2008.704

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