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Dynamic combinatorial libraries constructed on polymer scaffolds

Lookup NU author(s): Dr David Fulton

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Abstract

Functionalized polymers were prepared by grafting acylhydrazides onto a polyvinylbenzaldehyde scaffold through reversible hydrazone linkages. The dynamic nature of these linkages allows the functionalized polymers to exchange and reshuffle their appendages, and the resultant mixture of polymers can be considered as a dynamic combinatorial library constructed upon a polymer scaffold. The dynamic nature of these functionalized polymers was demonstrated.

Publication metadata

Author(s): Fulton DA

Publication type: Article

Publication status: Published

Journal: Organic Letters

Year: 2008

Volume: 10

Issue: 15

Pages: 3291-3294

ISSN (print): 1523-7060

ISSN (electronic): 1523-7052

Publisher: American Chemical Society

URL: http://dx.doi.org/10.1021/ol8011309

DOI: 10.1021/ol8011309

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