Toggle Main Menu Toggle Search

Open Access padlockePrints

Reactions of Pd(II) with Chelate-Tethered 2,6-Diaminopurine Derivatives: N3-Coordination and Reaction of the Purine System

Lookup NU author(s): David Amantia, Emeritus Professor Bill Clegg, Dr Ross Harrington, Professor Andrew Houlton

Downloads

Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


Abstract

Alkyldiamine-tethered derivatives of 2,6-diaminopurine, ethylenediamine-N9-propyl-2,6-diaminopurine, L1, and ethylenediamine-N9-ethyl-2,6-diaminopurine, L2, react with Pd(II) to give N3-coordinated complexes, However, the exact nature of the resulting complex is dependent on the reaction conditions. With PdCl2(MeCN)(2) in MeCN/H2O the expected [PdCl(N3-2,6-DAP-alkyl-en)](+) complex, 1, is formed with L1 chelating the metal center in a tridentate manner through the diamine function and N3 of the purine base. However, under the same conditions the shorter, ethyl-tethered, L2 gives a complex dication, 2, containing a tetradentate ligand forming simultaneously 5-, 6-, and 7-membered chelate rings. This resulting acetamidine, derived by addition to coordinated MeCN, appears to be the first such case involving the 2-amino group of a purine. The ethyl-analogue of 1, [PdCl(N3-2,6-DAP-Et-en)(+) 3, was prepared by reaction of L2 with K2PdCl4 in aqueous media.


Publication metadata

Author(s): Galindo MA, Amantia D, Martinez-Martinez A, Clegg W, Harrington RW, Martinez VM, Houlton A

Publication type: Article

Publication status: Published

Journal: Inorganic Chemistry

Year: 2009

Volume: 48

Issue: 23

Pages: 11085-11091

ISSN (print): 0020-1669

ISSN (electronic): 1520-510X

Publisher: American Chemical Society

URL: http://dx.doi.org/10.1021/ic901475y

DOI: 10.1021/ic901475y


Altmetrics

Altmetrics provided by Altmetric


Actions

Find at Newcastle University icon    Link to this publication


Share