Lookup NU author(s): Professor Ann Daly
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A new study reports that susceptibility to drug-induced liver injury by the cyclooxygenase 2 (COX-2) inhibitor lumiracoxib is associated with a human lymphocyte antigen (HLA) class II haplotype. This finding suggests that those at risk of hepatotoxicity can be identified by HLA genotyping, raising the possibility that lumiracoxib can be resurrected as a useful drug.
Author(s): Aithal GP, Daly AK
Publication type: Editorial
Publication status: Published
Journal: Nature Genetics
Print publication date: 01/08/2010
ISSN (print): 1061-4036
ISSN (electronic): 1546-1718
Publisher: Nature Publishing Group